||Accurate monitoring of urban regions and urban sprawls is critical to the detection and assessment of regional development. The nighttime light images of Defense Meteorological Satellite Program’s Operational Linescan System (DMSP/OLS) provide us direct solutions to make spatial descriptions of urban regions. Unfortunately, accurate monitoring of urban regions is apt to be hampered due to the shortages of the DMSP/OLS data. In this study, we utilized a new urban region extraction strategy based on the edge-detection method which is widely applied in automatic digital image processing. The edges of urban areas in Zhejiang province were identified based on the distributions and values of pixels. Compared with other traditional methods, the urban regions extracted in this study present a higher overall accuracy and kappa coefficient (OA = 93.1409%; Kappa = 0.8755). Two periods of the urban dynamic process and urban sprawl pattern in Zhejiang from 1992–2013 were further detected by the proposed method. At city level, the drastic increase in urban areas was found in cities of Hangzhou and Ningbo. This study provides an objective and convenient solution to the accurate identification of urban regions, which is also an important step to better understand the urban dynamics and urban development.