|   | 
Details
   web
Records
Author Taufique, S.K.T.; Prabhat, A.; Kumar, V.
Title Illuminated night alters hippocampal gene expressions and induces depressive-like responses in diurnal corvids Type Journal Article
Year 2018 Publication The European Journal of Neuroscience Abbreviated Journal Eur J Neurosci
Volume in press Issue Pages in press
Keywords Animals
Abstract Artificial light at night induces circadian disruptions and causes cognitive impairment and mood disorders; yet very little is known about the neural and molecular correlates of these effects in diurnal animals. We manipulated the night environment and examined cellular and molecular changes in hippocampus, the brain region involved in cognition and mood, of Indian house crows (Corvus splendens) exposed to 12 h light (150 lux): 12 h darkness (0 lux). Diurnal corvids are an ideal model species with cognitive abilities at par with mammals. Dim light (6 lux) at night (dLAN) altered daily activity:rest pattern, reduced sleep and induced depressive-like responses (decreased eating and self-grooming, self-mutilation and reduced novel object exploration); return to an absolute dark night reversed these negative effects. dLAN suppressed nocturnal melatonin levels, however, diurnal corticosterone levels were unaffected. Concomitant reduction of immunoreactivity for DCX and BDNF suggested dLAN-induced suppression of hippocampal neurogenesis and compromised neuronal health. dLAN also negatively influenced hippocampal expression of genes associated with depressive-like responses (bdnf, il-1beta, tnfr1, nr4a2), but not of those associated with neuronal plasticity (egr1, creb, syngap, syn2, grin2a, grin2b), cellular oxidative stress (gst, sod3, cat1) and neuronal death (caspase2, caspase3, foxo3). Furthermore, we envisaged the role of BDNF and showed epigenetic modification of bdnf gene by decreased histone H3 acetylation and increased hdac4 expression under dLAN. These results demonstrate transcriptional and epigenetic bases of dLAN-induced negative effects in diurnal crows, and provide insights into the risks of exposure to illuminated nights to animals including humans in an urban setting. This article is protected by copyright. All rights reserved.
Address IndoUS Center for Biological Timing Department of Zoology, University of Delhi, Delhi, 110 007, India
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0953-816X ISBN Medium
Area Expedition Conference
Notes PMID:30218624 Approved no
Call Number GFZ @ kyba @ Serial 2010
Permanent link to this record
 

 
Author Park, C.Y.
Title Night Light Pollution and Ocular Fatigue Type Journal Article
Year 2018 Publication Journal of Korean Medical Science Abbreviated Journal J Korean Med Sci
Volume 33 Issue 38 Pages e257
Keywords Commentary; Human Health
Abstract
Address Department of Ophthalmology, Dongguk University, Ilsan Hospital, Goyang, Korea
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1011-8934 ISBN Medium
Area Expedition Conference
Notes PMID:30220898; PMCID:PMC6137033 Approved no
Call Number GFZ @ kyba @ Serial 2011
Permanent link to this record
 

 
Author McGlashan, E.M.; Nandam, L.S.; Vidafar, P.; Mansfield, D.R.; Rajaratnam, S.M.W.; Cain, S.W.
Title The SSRI citalopram increases the sensitivity of the human circadian system to light in an acute dose Type Journal Article
Year 2018 Publication Psychopharmacology Abbreviated Journal Psychopharmacology (Berl)
Volume in press Issue Pages in press
Keywords Human Health
Abstract RATIONALE: Disturbances of the circadian system are common in depression. Though they typically subside when depression is treated with antidepressants, the mechanism by which this occurs is unknown. Despite being the most commonly prescribed class of antidepressants, the effect of selective serotonin reuptake inhibitors (SSRIs) on the human circadian clock is not well understood. OBJECTIVE: To examine the effect of the SSRI citalopram (30 mg) on the sensitivity of the human circadian system to light. METHODS: This study used a double-blind, placebo-controlled, within-subjects, crossover design. Participants completed two melatonin suppression assessments in room level light (~ 100 lx), taking either a single dose of citalopram 30 mg or a placebo at the beginning of each light exposure. Melatonin suppression was calculated by comparing placebo and citalopram light exposure conditions to a dim light baseline. RESULTS: A 47% increase in melatonin suppression was observed after administration of an acute dose of citalopram, with all participants showing more suppression after citalopram administration (large effect, d = 1.54). Further, melatonin onset occurred later under normal room light with citalopram compared to placebo. CONCLUSIONS: Increased sensitivity of the circadian system to light could assist in explaining some of the inter-individual variability in antidepressant treatment responses, as it is likely to assist in recovery in some patients, while causing further disruption for others.
Address Monash Institute of Cognitive and Clinical Neurosciences, School of Psychological Sciences, Monash University, 18 Innovation Walk, Clayton, VIC, 3800, Australia. sean.cain@monash.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0033-3158 ISBN Medium
Area Expedition Conference
Notes PMID:30219986 Approved no
Call Number GFZ @ kyba @ Serial 2012
Permanent link to this record
 

 
Author Kurvers, R.H.J.M.; Drägestein, J.; Hölker, F.; Jechow, A.; Krause, J.; Bierbach, D.
Title Artificial Light at Night Affects Emergence from a Refuge and Space Use in Guppies Type Journal Article
Year 2018 Publication Scientific Reports Abbreviated Journal Sci Rep
Volume 8 Issue 1 Pages
Keywords Animals
Abstract Artificial light at night (ALAN) is a major form of anthropogenic pollution. ALAN is well known to affect different behaviours during nighttime, when changes in light conditions often have immediate consequences for the trade-offs individuals experience. How ALAN affects daytime behaviours, however, has received far less attention. Here we studied how ALAN affected daytime personality traits and learning ability. We exposed Trinidadian guppies, Poecilia reticulata, for 10 weeks to different ALAN levels: bright light (24 hrs bright light, ~5,000 lx), dim light (12 hrs bright light; 12 hrs dim light, ~0.5 lx) and control (12 hrs bright light; 12 hrs dark). Afterwards, we tested how the treatments affected diurnal emergence from a refuge, space use, activity, sociability and the ability to memorize the location of companion fish. Individuals exposed to the light treatments (both dim and bright light) emerged quicker from a refuge and fish from the bright light treatment spent relatively more time in the open area of the arena. ALAN did not affect any of the other behaviours, although memory could not be tested since fish did not learn the companions’ location. Our results demonstrate that ALAN, next to affecting nocturnal behaviours, can also affect key diurnal behavioural processes, associated with risk-taking.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2045-2322 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 2013
Permanent link to this record
 

 
Author Kinzey, B.R.; Perrin, T.E.; Miller, N.J.; Kocifaj, M.; Aubé, M.; Lamphar, H.A.
Title An investigation of LED street lighting's impact on sky glow Type Journal Article
Year 2017 Publication Abbreviated Journal
Volume PNNL-26411 Issue Pages
Keywords Skyglow; Lighting
Abstract A significant amount of public attention has recently focused on perceived impacts of converting street lighting from incumbent lamp-based products to LED technology. Much of this attention pertains to the higher content of short wavelength light (commonly referred to as “blue light”) of LEDs and its attendant influences on sky glow (a brightening of the night sky that can interfere with astronomical observation and may be associated with a host of other issues). The complexity of this topic leads to common misunderstandings and misperceptions among the public, and for this reason the U.S. Department of Energy Solid-State Lighting Program embarked on a study of sky glow using a well-established astronomical model to investigate some of the primary factors influencing sky glow. This report details the results of the investigation and attempts to present those results in terms accessible to the general lighting community. The report also strives to put the results into a larger context, and help educate interested readers on various topics relevant to the issues being discussed.
Address
Corporate Author Pacific Northwest National Lab. (PNNL), Richland, WA (United States) Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 2014
Permanent link to this record