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Author Kijlstra, A.; Tian, Y.; Kelly, E.R.; Berendschot, T.T.J.M.
Title Lutein: more than just a filter for blue light Type Journal Article
Year 2012 Publication Progress in Retinal and eye Research Abbreviated Journal Prog Retin Eye Res
Volume 31 Issue 4 Pages 303-315
Keywords Animals; Biological Transport/physiology; Eye/metabolism; Humans; Lutein/chemistry/deficiency/pharmacology/*physiology; Macular Degeneration/etiology/prevention & control; Retinal Diseases/metabolism; Scavenger Receptors, Class B/physiology; blue light
Abstract Lutein is concentrated in the primate retina, where together with zeaxanthin it forms the macular pigment. Traditionally lutein is characterized by its blue light filtering and anti-oxidant properties. Eliminating lutein from the diet of experimental animals results in early degenerative signs in the retina while patients with an acquired condition of macular pigment loss (Macular Telangiectasia) show serious visual handicap indicating the importance of macular pigment. Whether lutein intake reduces the risk of age related macular degeneration (AMD) or cataract formation is currently a strong matter of debate and abundant research is carried out to unravel the biological properties of the lutein molecule. SR-B1 has recently been identified as a lutein binding protein in the retina and this same receptor plays a role in the selective uptake in the gut. In the blood lutein is transported via high-density lipoproteins (HDL). Genes controlling SR-B1 and HDL levels predispose to AMD which supports the involvement of cholesterol/lutein transport pathways. Apart from beneficial effects of lutein intake on various visual function tests, recent findings show that lutein can affect immune responses and inflammation. Lutein diminishes the expression of various ocular inflammation models including endotoxin induced uveitis, laser induced choroidal neovascularization, streptozotocin induced diabetes and experimental retinal ischemia and reperfusion. In vitro studies show that lutein suppresses NF kappa-B activation as well as the expression of iNOS and COX-2. Since AMD has features of a chronic low-grade systemic inflammatory response, attention to the exact role of lutein in this disease has shifted from a local effect in the eye towards a possible systemic anti-inflammatory function.
Address University Eye Clinic Maastricht, Maastricht, The Netherlands. aize.kijlstra@wur.nl
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Language English Summary Language Original Title
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Series Volume Series Issue Edition
ISSN 1350-9462 ISBN Medium
Area Expedition Conference
Notes PMID:22465791 Approved no
Call Number IDA @ john @ Serial 343
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Author Henderson, J.V.; Storeygard, A.; Weil, D.N.
Title Measuring Economic Growth From Outer Space Type Journal Article
Year 2012 Publication The American Economic Review Abbreviated Journal Am Econ Rev
Volume 102 Issue 2 Pages 994-1028
Keywords satellite data; remote sensing; economics; social science
Abstract GDP growth is often measured poorly for countries and rarely measured at all for cities or subnational regions. We propose a readily available proxy: satellite data on lights at night. We develop a statistical framework that uses lights growth to augment existing income growth measures, under the assumption that measurement error in using observed light as an indicator of income is uncorrelated with measurement error in national income accounts. For countries with good national income accounts data, information on growth of lights is of marginal value in estimating the true growth rate of income, while for countries with the worst national income accounts, the optimal estimate of true income growth is a composite with roughly equal weights. Among poor-data countries, our new estimate of average annual growth differs by as much as 3 percentage points from official data. Lights data also allow for measurement of income growth in sub- and supranational regions. As an application, we examine growth in Sub Saharan African regions over the last 17 years. We find that real incomes in non-coastal areas have grown faster by 1/3 of an annual percentage point than coastal areas; non-malarial areas have grown faster than malarial ones by 1/3 to 2/3 annual percent points; and primate city regions have grown no faster than hinterland areas. Such applications point toward a research program in which “empirical growth” need no longer be synonymous with “national income accounts.”
Address National Bureau of Economic Research, 1050 Massachusetts Avenue, Cambridge, MA 02138
Corporate Author (down) Thesis
Publisher American Economic Association Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0002-8282 ISBN Medium
Area Expedition Conference
Notes PMID:25067841; PMCID:PMC4108272 Approved no
Call Number IDA @ john @ Serial 364
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Author Hölker, F.; Moss, T.; Griefahn, B.; Kloas, W.; Voigt, C.; et al.
Title The Dark Side of Light: A Transdisciplinary Research Agenda for Light Pollution Policy Type Journal Article
Year 2010 Publication Ecol Soc Abbreviated Journal
Volume 15 Issue 4 Pages
Keywords Ecology; artificial light; energy efficiency; lighting concept; light pollution; nightscape; policy; sustainability; transdisciplinary
Abstract Although the invention and widespread use of artificial light is clearly one of the most important human technological advances, the transformation of nightscapes is increasingly recognized as having adverse effects. Night lighting may have serious physiological consequences for humans, ecological and evolutionary implications for animal and plant populations, and may reshape entire ecosystems. However, knowledge on the adverse effects of light pollution is vague. In response to climate change and energy shortages, many countries, regions, and communities are developing new lighting programs and concepts with a strong focus on energy efficiency and greenhouse gas emissions. Given the dramatic increase in artificial light at night (0 – 20% per year, depending on geographic region), we see an urgent need for light pollution policies that go beyond energy efficiency to include human well-being, the structure and functioning of ecosystems, and inter-related socioeconomic consequences. Such a policy shift will require a sound transdisciplinary understanding of the significance of the night, and its loss, for humans and the natural systems upon which we depend. Knowledge is also urgently needed on suitable lighting technologies and concepts which are ecologically, socially, and economically sustainable. Unless managing darkness becomes an integral part of future conservation and lighting policies, modern society may run into a global self-experiment with unpredictable outcomes.
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Call Number LoNNe @ christopher.kyba @ Serial 478
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Author Farahat, A.; Florea, A.; Martinez Lastra, J.L.; Branas, C.
Title Energy Efficiency Considerations for LED-based Lighting of Multipurpose Outdoor Environments Type Journal Article
Year 2015 Publication IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensingournal of Emerging and Selected Topics in Power Electronics Abbreviated Journal IEEE J. Emerging and Sel. Topics in Power Elec.
Volume PP Issue 99 Pages 1
Keywords Lighting; LED lighting; LED; optimization; lighting technology; lighting design; energy; energy efficiency
Abstract Nowadays street lighting accounts for 53% of outdoor lighting use and the market is continuously increasing. In the context of rising energy prices and growing environmental awareness, energy efficiency is becoming one of the most important criteria for street lighting systems design. LED-based lights have become the primary option for replacing conventional light bulbs, being digitally controllable, small, highly efficient, and cheap to manufacture. Advanced control strategies adapted to ambient conditions are needed to combine low energy consumption and high quality light ambience according to changing specifications. This paper describes an outdoor lighting solution aimed at energy efficient performance in the context of multipurpose outdoor environments, where control is crucial in achieving efficiency improvements. The work addresses efficiency at the component level, by optimizing the performance of LED drivers, and at system level, defining the control strategy and associated hardware infrastructure. The approach designed was tested in a real environment. The performance of the lighting installation was assessed using the web-based monitoring application, providing real-time consumption information and aggregated historical data.
Address University of Technology, Tampere, Finland.(Email: ahmed.amr.b@gmail.com)
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Publisher IEEE Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2168-6777 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number IDA @ john @ Serial 1205
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Author Eisenstein, M.
Title Chronobiology: stepping out of time Type Journal Article
Year 2013 Publication Nature Abbreviated Journal Nature
Volume 497 Issue 7450 Pages S10-2
Keywords Human Health; Animals; Benzofurans/therapeutic use; CLOCK Proteins/genetics/metabolism; Circadian Rhythm/genetics/*physiology; Cyclopropanes/therapeutic use; Efficiency/physiology; Humans; Melatonin/agonists/metabolism; Obesity/metabolism; Sleep/genetics/*physiology; Suprachiasmatic Nucleus/metabolism
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
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ISSN 0028-0836 ISBN Medium
Area Expedition Conference
Notes PMID:23698500 Approved no
Call Number LoNNe @ christopher.kyba @ Serial 500
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