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Author Zschokke, S.; Herberstein, M.E.
Title Laboratory Methods For Maintaining And Studying Web-Building Spiders Type Journal Article
Year 2005 Publication Journal of Arachnology Abbreviated Journal Journal of Arachnology
Volume 33 Issue 2 Pages 205-213
Keywords Animals; data collection; in various scien-; laboratory manual; methodology; popular model; spider silk; spider web; system to address questions; web-building spiders
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ISSN 0161-8202 ISBN Medium
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Notes Approved no
Call Number LoNNe @ kagoburian @ Serial 677
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Author Nguyen, B.P.; Postma, E.; Ekkers, D.; Degener, F.; Mejier, T.
Title Bad Kissingen : a blueprint for future urban design Type Report
Year 2013 Publication University Groningen Abbreviated Journal
Volume Issue Pages
Keywords chronobiology, economy, society, urban design
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Call Number LoNNe @ schroer @ Serial 1061
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Author Aschoff, J.; Knauth, P.; Rutenfranz, J.
Title Biologische Rhythmen, in Psychobiologie Type Journal Article
Year 1988 Publication Grundlagen des Verhaltens, edited by K. Immelmann, K. R. Scherer, C. Vogel and P. Schmoock Abbreviated Journal
Volume Issue Pages 219-256
Keywords Society
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Call Number LoNNe @ kagoburian @ Serial 716
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Author Blask, D.E.; Brainard, G.C.; Dauchy, R.T.; Hanifin, J.P.; Davidson, L.K.; Krause, J.A.; Sauer, L.A.; Rivera-Bermudez, M.A.; Dubocovich, M.L.; Jasser, S.A.; Lynch, D.T.; Rollag, M.D.; Zalatan, F.
Title Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats Type Journal Article
Year 2005 Publication Cancer Research Abbreviated Journal Cancer Res
Volume 65 Issue 23 Pages 11174-11184
Keywords Human Health; Animals; Breast Neoplasms/*blood/genetics/pathology; Cell Growth Processes/physiology; Circadian Rhythm/*physiology; Female; Humans; Light; Liver Neoplasms, Experimental/metabolism; Male; Melatonin/blood/*deficiency; Premenopause/blood; RNA, Messenger/biosynthesis/genetics; Rats; Rats, Nude; Receptors, Melatonin/biosynthesis/genetics; Transplantation, Heterologous
Abstract The increased breast cancer risk in female night shift workers has been postulated to result from the suppression of pineal melatonin production by exposure to light at night. Exposure of rats bearing rat hepatomas or human breast cancer xenografts to increasing intensities of white fluorescent light during each 12-hour dark phase (0-345 microW/cm2) resulted in a dose-dependent suppression of nocturnal melatonin blood levels and a stimulation of tumor growth and linoleic acid uptake/metabolism to the mitogenic molecule 13-hydroxyoctadecadienoic acid. Venous blood samples were collected from healthy, premenopausal female volunteers during either the daytime, nighttime, or nighttime following 90 minutes of ocular bright, white fluorescent light exposure at 580 microW/cm2 (i.e., 2,800 lx). Compared with tumors perfused with daytime-collected melatonin-deficient blood, human breast cancer xenografts and rat hepatomas perfused in situ, with nocturnal, physiologically melatonin-rich blood collected during the night, exhibited markedly suppressed proliferative activity and linoleic acid uptake/metabolism. Tumors perfused with melatonin-deficient blood collected following ocular exposure to light at night exhibited the daytime pattern of high tumor proliferative activity. These results are the first to show that the tumor growth response to exposure to light during darkness is intensity dependent and that the human nocturnal, circadian melatonin signal not only inhibits human breast cancer growth but that this effect is extinguished by short-term ocular exposure to bright, white light at night. These mechanistic studies are the first to provide a rational biological explanation for the increased breast cancer risk in female night shift workers.
Address Laboratory of Chrono-Neuroendocrine Oncology, Bassett Research Institute, The Mary Imogene Bassett Hospital, Cooperstown, New York 13326, USA. david.blask@bassett.org
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Language English Summary Language Original Title
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ISSN 0008-5472 ISBN Medium
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Notes PMID:16322268 Approved no
Call Number LoNNe @ kagoburian @ Serial 721
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Author Edensor, T.
Title The Gloomy City: Rethinking the Relationship between Light and Dark Type Journal Article
Year 2013 Publication Urban Studies Abbreviated Journal
Volume 52 Issue 3 Pages 422-438
Keywords Society
Abstract Given geography’s neglect of illuminated and dark space, this paper explores the various qualities of darkness that have contributed to the experience of the city. In recent history, darkness has been conceptualised negatively, for instance, with the ‘dark side’ and the ‘forces of darkness’ conceived as the opposite of that which enlightens and illuminates. Perhaps such metaphors testify to earlier urban conditions in which perils of all sorts lurked in the nocturnal city and doors were closed when darkness fell. Yet modern illumination has transformed nocturnal urban experience, producing cityscapes of regulation, hierarchical selectiveness, consumption, fantasy and imagination. However, this article suggests that the more positive qualities of darkness have been overlooked: the potential for conviviality and intimacy to be fostered in the dark, the aesthetics and atmospherics of darkness and shadow, the possibilities for apprehending the world through other senses and the dismissal of the star-saturated sky.
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Notes Approved no
Call Number LoNNe @ kagoburian @ Serial 739
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