||How to estimate regional economic development level is important for solving regional inequality problems. Most of previous studies on regional economic development are based on the statistics collected typically in administrative units. This paper has analyzed the defects of traditional studies, and attempted to research regional economic development problems with 10-year DMSP/OLS nighttime light satellite imagery as a new data source. For exploring the relationship between DMSP/OLS nighttime light data and GDP, different types of curve fitting regression models have been tried, the Cubic model has shown the best performance with a coefficient of determination (R2) equal to 0.803. Based on this positive correlation, we have estimated provincial economic development level of China using DMSP/OLS nighttime light data. The research results have indicated that the DMSP/OLS nighttime light data can well reveal provincial economic development levels.