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Author Lowden, A.; Akerstedt, T. url  doi
openurl 
  Title (up) Assessment of a new dynamic light regimen in a nuclear power control room without windows on quickly rotating shiftworkers--effects on health, wakefulness, and circadian alignment: a pilot study Type Journal Article
  Year 2012 Publication Chronobiology International Abbreviated Journal Chronobiol Int  
  Volume 29 Issue 5 Pages 641-649  
  Keywords Adaptation, Physiological; Adult; *Circadian Rhythm; Darkness/adverse effects; *Environment, Controlled; Female; Humans; *Light; Male; Melatonin/metabolism; Middle Aged; Photic Stimulation; Pilot Projects; Saliva/chemistry; Sleep/*physiology; *Wakefulness; *Work Schedule Tolerance  
  Abstract The aim of the study was to test whether a new dynamic light regime would improve alertness, sleep, and adaptation to rotating shiftwork. The illumination level in a control room without windows at a nuclear power station was ~200 lux (straight-forward horizontal gaze) using a weak yellow light of 200 lux, 3000 K (Philips Master TLD 36 W 830). New lighting equipment was installed in one area of the control room above the positions of the reactor operators. The new lights were shielded from the control group by a distance of >6 m, and the other operators worked at desks turned away from the new light. The new lights were designed to give three different light exposures: (i) white/blue strong light of 745 lux, 6000 K; (ii) weak yellow light of 650 lux, 4000 K; and (iii) yellow moderate light of 700 lux, 4000 K. In a crossover design, the normal and new light exposures were given during a sequence of three night shifts, two free days, two morning shifts, and one afternoon shift (NNN + MMA), with 7 wks between sessions. The operators consisted of two groups; seven reactor operators from seven work teams were at one time exposed to the new equipment and 16 other operators were used as controls. The study was conducted during winter with reduced opportunities of daylight exposure during work, after night work, or before morning work. Operators wore actigraphs, filled in a sleep/wake diary, including ratings of sleepiness on the Karolinska Sleepiness Scale (KSS) every 2 h, and provided saliva samples for analysis of melatonin at work (every 2nd h during one night shift and first 3 h during one morning shift). Results from the wake/sleep diary showed the new light treatment increased alertness during the 2nd night shift (interaction group x light x time, p < .01). Time of waking was delayed in the light condition after the 3rd night shift (group x light, p < .05), but the amount of wake time during the sleep span increased after the 2nd night shift (p < .05), also showing a tendency to affect sleep efficiency (p < .10). Effects on circadian phase were difficult to establish given the small sample size and infrequent sampling of saliva melatonin. Nonetheless, it seems that appropriate dynamic light in rooms without windows during the dark Nordic season may promote alertness, sleep, and better adaptation to quickly rotating shiftwork.  
  Address Stress Research Institute, Stockholm University, Stockholm, Sweden. arne.lowden@stress.su.se  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
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  Series Volume Series Issue Edition  
  ISSN 0742-0528 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:22621361 Approved no  
  Call Number IDA @ john @ Serial 148  
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Author Nadis, S. url  doi
openurl 
  Title (up) Biologists join drive to turn down the lights Type
  Year 2002 Publication Nature Abbreviated Journal Nature  
  Volume 419 Issue 6910 Pages 868  
  Keywords Ecology; Animal Migration; Animals; Astronomical Phenomena; Astronomy; Biology/*trends; Breast Neoplasms/etiology; Environment; Environmental Pollution/*adverse effects/prevention & control; Female; Humans; Light/*adverse effects; Male; Risk Factors; Vision, Ocular/physiology  
  Abstract  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0028-0836 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:12410271 Approved no  
  Call Number LoNNe @ kagoburian @ Serial 787  
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Author Kayumov, L.; Casper, R.F.; Hawa, R.J.; Perelman, B.; Chung, S.A.; Sokalsky, S.; Shapiro, C.M. url  doi
openurl 
  Title (up) Blocking low-wavelength light prevents nocturnal melatonin suppression with no adverse effect on performance during simulated shift work Type Journal Article
  Year 2005 Publication The Journal of Clinical Endocrinology and Metabolism Abbreviated Journal J Clin Endocrinol Metab  
  Volume 90 Issue 5 Pages 2755-2761  
  Keywords Lighting; Adult; *Circadian Rhythm; Female; Humans; *Light; Male; Melatonin/*secretion; *Work Schedule Tolerance  
  Abstract Decreases in melatonin production in human and animals are known to be caused by environmental lighting, especially short-wavelength lighting (between 470 and 525 nm). We investigated the novel hypothesis that the use of goggles with selective exclusion of all wavelengths less than 530 nm could prevent the suppression of melatonin in bright-light conditions during a simulated shift-work experiment. Salivary melatonin levels were measured under dim (<5 lux), bright (800 lux), and filtered (800 lux) light at hourly intervals between 2000 and 0800 h in 11 healthy young males and eight females (mean age, 24.7 +/- 4.6 yr). The measurements were performed during three nonconsecutive nights over a 2-wk period. Subjective sleepiness was measured by self-report scales, whereas objective performance was assessed with the Continuous Performance Test. All subjects demonstrated preserved melatonin levels in filtered light similar to their dim-light secretion profile. Unfiltered bright light drastically suppressed melatonin production. Normalization of endogenous melatonin production while wearing goggles did not impair measures of performance, subjective sleepiness, or alertness.  
  Address Sleep Research Laboratory, Department of Psychiatry, University Health Network, ECW 3D-035, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8. lkayumov@uhnres.utoronto.ca  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0021-972X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:15713707 Approved no  
  Call Number LoNNe @ kagoburian @ Serial 640  
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Author Knutsson, A.; Alfredsson, L.; Karlsson, B.; Akerstedt, T.; Fransson, E.I.; Westerholm, P.; Westerlund, H. url  doi
openurl 
  Title (up) Breast cancer among shift workers: results of the WOLF longitudinal cohort study Type Journal Article
  Year 2013 Publication Scandinavian Journal of Work, Environment & Health Abbreviated Journal Scand J Work Environ Health  
  Volume 39 Issue 2 Pages 170-177  
  Keywords Adult; Aged; Breast Neoplasms/*epidemiology/etiology; Circadian Rhythm; Female; Humans; Incidence; Longitudinal Studies; Middle Aged; Proportional Hazards Models; Risk Assessment; Sweden/epidemiology; *Work Schedule Tolerance; oncogenesis  
  Abstract OBJECTIVE: The aim of this study was to investigate whether shift work (with or without night work) is associated with increased risk of breast cancer. METHODS: The population consisted of 4036 women. Data were obtained from WOLF (Work, Lipids, and Fibrinogen), a longitudinal cohort study. Information about baseline characteristics was based on questionnaire responses and medical examination. Cancer incidence from baseline to follow-up was obtained from the national cancer registry. Two exposure groups were identified: shift work with and without night work. The group with day work only was used as the reference group in the analysis. Cox regression analysis was used to calculate relative risk. RESULTS: In total, 94 women developed breast cancer during follow-up. The average follow-up time was 12.4 years. The hazard ratio for breast cancer was 1.23 [95% confidence interval (95% CI) 0.70-2.17] for shifts without night work and 2.02 (95% CI 1.03-3.95) for shifts with night work. When including only women <60 years of age, the risk estimates were 1.18 (95% CI 0.67-2.07) for shifts without night work, and 2.15 (95% CI 1.10-4.21) for shifts with night work. CONCLUSIONS: Our results indicate an increased risk for breast cancer among women who work shifts that includes night work.  
  Address Department of Health Sciences, Mid Sweden University, Sundsvall. Sweden. Anders.Knutsson@miun.se  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0355-3140 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23007867 Approved no  
  Call Number IDA @ john @ Serial 154  
Permanent link to this record
 

 
Author Kantermann, T. url  doi
openurl 
  Title (up) Circadian biology: sleep-styles shaped by light-styles Type Journal Article
  Year 2013 Publication Current Biology : CB Abbreviated Journal Curr Biol  
  Volume 23 Issue 16 Pages R689-90  
  Keywords Human Health; Circadian Clocks/*radiation effects; Female; Humans; *Lighting; Male; *Photoperiod; *Sunlight  
  Abstract Light and darkness are the main time cues synchronising all biological clocks to the external environment. This little understood evolutionary phenomenon is called circadian entrainment. A new study illuminates our understanding of how modern light- and lifestyles compromise circadian entrainment and impact our biological clocks.  
  Address Chronobiology – Centre for Behaviour and Neurosciences, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands. thomas@kantermann.de  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0960-9822 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23968925 Approved no  
  Call Number LoNNe @ christopher.kyba @ Serial 501  
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