toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
Details
   print
  Records Links
Author Figueiro, M.G.; Sahin, L.; Wood, B.; Plitnick, B. url  doi
openurl 
  Title Light at Night and Measures of Alertness and Performance: Implications for Shift Workers Type Journal Article
  Year 2015 Publication (up) Biological Research for Nursing Abbreviated Journal Biol Res Nurs  
  Volume Issue Pages  
  Keywords Human Health; GO/NOGO test; alertness; melatonin; red light; shift work  
  Abstract Rotating-shift workers, particularly those working at night, are likely to experience sleepiness, decreased productivity, and impaired safety while on the job. Light at night has been shown to have acute alerting effects, reduce sleepiness, and improve performance. However, light at night can also suppress melatonin and induce circadian disruption, both of which have been linked to increased health risks. Previous studies have shown that long-wavelength (red) light exposure increases objective and subjective measures of alertness at night, without suppressing nocturnal melatonin. This study investigated whether exposure to red light at night would not only increase measures of alertness but also improve performance. It was hypothesized that exposure to both red (630 nm) and white (2,568 K) lights would improve performance but that only white light would significantly affect melatonin levels. Seventeen individuals participated in a 3-week, within-subjects, nighttime laboratory study. Compared to remaining in dim light, participants had significantly faster reaction times in the GO/NOGO test after exposure to both red light and white light. Compared to dim light exposure, power in the alpha and alpha-theta regions was significantly decreased after exposure to red light. Melatonin levels were significantly suppressed by white light only. Results show that not only can red light improve measures of alertness, but it can also improve certain types of performance at night without affecting melatonin levels. These findings could have significant practical applications for nurses; red light could help nurses working rotating shifts maintain nighttime alertness, without suppressing melatonin or changing their circadian phase.  
  Address Lighting Research Center, Rensselaer Polytechnic Institute, New York, NY, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1099-8004 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:25697165 Approved no  
  Call Number LoNNe @ christopher.kyba @ Serial 1110  
Permanent link to this record
 

 
Author Hunter, C.M.; Figueiro, M.G. url  doi
openurl 
  Title Measuring Light at Night and Melatonin Levels in Shift Workers: A Review of the Literature Type Journal Article
  Year 2017 Publication (up) Biological Research for Nursing Abbreviated Journal Biol Res Nurs  
  Volume 19 Issue 4 Pages 365-374  
  Keywords Human Health; Review  
  Abstract Shift work, especially that involving rotating and night shifts, is associated with an increased risk of diseases, including cancer. Attempts to explain the association between shift work and cancer in particular have focused on the processes of melatonin production and suppression. One hypothesis postulates that exposure to light at night (LAN) suppresses melatonin, whose production is known to slow the development of cancerous cells, while another proposes that circadian disruption associated with shift work, and not just LAN, increases health risks. This review focuses on six studies that employed quantitative measurement of LAN and melatonin levels to assess cancer risks in shift workers. These studies were identified via searching the PubMed database for peer-reviewed, English-language articles examining the links between shift work, LAN, and disease using the terms light at night, circadian disruption, health, risk, cancer, shift work, or rotating shift. While the results indicate a growing consensus on the relationship between disease risks (particularly cancer) and circadian disruption associated with shift work, the establishment of a direct link between LAN and disease has been impeded by contradictory studies and a lack of consistent, quantitative methods for measuring LAN in the research to date. Better protocols for assessing personal LAN exposure are required, particularly those employing calibrated devices that measure and sample exposure to workplace light conditions, to accurately assess LAN's effects on the circadian system and disease. Other methodologies, such as measuring circadian disruption and melatonin levels in the field, may also help to resolve discrepancies in the findings.  
  Address 1 Lighting Research Center, Rensselaer Polytechnic Institute, Troy, NY, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1099-8004 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28627309; PMCID:PMC5862149 Approved no  
  Call Number GFZ @ kyba @ Serial 2458  
Permanent link to this record
 

 
Author Foster, R.G.; Hughes, S.; Peirson, S.N. url  doi
openurl 
  Title Circadian Photoentrainment in Mice and Humans Type Journal Article
  Year 2020 Publication (up) Biology Abbreviated Journal Biology (Basel)  
  Volume 9 Issue 7 Pages  
  Keywords Review; Animals; Human Health; circadian; entrainment; human; melanopsin (OPN4); mouse; photoreceptor  
  Abstract Light around twilight provides the primary entrainment signal for circadian rhythms. Here we review the mechanisms and responses of the mouse and human circadian systems to light. Both utilize a network of photosensitive retinal ganglion cells (pRGCs) expressing the photopigment melanopsin (OPN4). In both species action spectra and functional expression of OPN4 in vitro show that melanopsin has a lambdamax close to 480 nm. Anatomical findings demonstrate that there are multiple pRGC sub-types, with some evidence in mice, but little in humans, regarding their roles in regulating physiology and behavior. Studies in mice, non-human primates and humans, show that rods and cones project to and can modulate the light responses of pRGCs. Such an integration of signals enables the rods to detect dim light, the cones to detect higher light intensities and the integration of intermittent light exposure, whilst melanopsin measures bright light over extended periods of time. Although photoreceptor mechanisms are similar, sensitivity thresholds differ markedly between mice and humans. Mice can entrain to light at approximately 1 lux for a few minutes, whilst humans require light at high irradiance (>100's lux) and of a long duration (>30 min). The basis for this difference remains unclear. As our retinal light exposure is highly dynamic, and because photoreceptor interactions are complex and difficult to model, attempts to develop evidence-based lighting to enhance human circadian entrainment are very challenging. A way forward will be to define human circadian responses to artificial and natural light in the “real world” where light intensity, duration, spectral quality, time of day, light history and age can each be assessed.  
  Address Sleep & Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, Sir William Dunn School of Pathology, Oxford Molecular Pathology Institute, South Parks Road, University of Oxford, Oxford OX1 3RF, UK  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2079-7737 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:32708259; PMCID:PMC7408241 Approved no  
  Call Number GFZ @ kyba @ Serial 3082  
Permanent link to this record
 

 
Author Li, Y.; Cheng, S.; Li, L.; Zhao, Y.; Shen, W.; Sun, X. url  doi
openurl 
  Title Light-exposure at night impairs mouse ovary development via cell apoptosis and DNA damage Type Journal Article
  Year 2019 Publication (up) Bioscience Reports Abbreviated Journal Biosci Rep  
  Volume 39 Issue Pages BSR20181464  
  Keywords Human Health; Animals; mouse models; ovaries  
  Abstract The alternation of light and dark rhythm causes a series of physiological, biochemical and metabolic changes in animals, which also alters the growth and development of animals, and feeding, migration, reproduction and other behavioral activities. In recent years, many studies have reported the effects of long-term (more than 6 weeks) illumination on ovarian growth and development. In this study, we observed the damage, repair and apoptosis of ovarian DNA in a short period of illumination. The results showed that, in short time (less than 2 weeks) illumination conditions, the 24 hrs-light treatment caused the reduction of total ovarian follicle number and downregulation of circadian clock related genes. Furthermore, the changed levels of serum sex hormones were also detected after 24 hrs-light exposure, of which the concentrations of LH (luteinizing hormone), FSH (follicle-stimulating hormone) and E2 (estradiol) were increased, but the concentration of PROG (progesterone) was decreased. Moreover, 24 hrs-light exposure increased the expression of DNA damage and repair related genes, the number of TUNEL and RAD51 positive cells. These results indicated that 24 hrs-light exposure for 4 days, 8days and 12 days increased DNA damage and cell apoptosis, thereby affecting the development of ovary.  
  Address Qingdao agricultural university, Qingdao, China; xfsun@qau.edu.cn  
  Corporate Author Thesis  
  Publisher Portland Press Place of Publication Editor  
  Language English Summary Language English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0144-8463 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30962269 Approved no  
  Call Number GFZ @ kyba @ Serial 2293  
Permanent link to this record
 

 
Author Phelps, J. url  doi
openurl 
  Title A powerful non-pharmacologic treatment for mania – virtually Type Journal Article
  Year 2016 Publication (up) Bipolar Disorders Abbreviated Journal Bipolar Disord  
  Volume 18 Issue 4 Pages 379-382  
  Keywords Commentary; Human Health  
  Abstract  
  Address Samaritan Mental Health, Corvallis, OR, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1398-5647 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27218661 Approved no  
  Call Number LoNNe @ kyba @ Serial 1511  
Permanent link to this record
Select All    Deselect All
 |   | 
Details
   print

Save Citations:
Export Records: