toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
Details
   print
  Records Links
Author Chellappa, S.L.; Steiner, R.; Oelhafen, P.; Lang, D.; Gotz, T.; Krebs, J.; Cajochen, C. url  doi
openurl 
  Title (up) Acute exposure to evening blue-enriched light impacts on human sleep Type Journal Article
  Year 2013 Publication Journal of Sleep Research Abbreviated Journal J Sleep Res  
  Volume 22 Issue 5 Pages 573-580  
  Keywords Human Health  
  Abstract Light in the short wavelength range (blue light: 446-483 nm) elicits direct effects on human melatonin secretion, alertness and cognitive performance via non-image-forming photoreceptors. However, the impact of blue-enriched polychromatic light on human sleep architecture and sleep electroencephalographic activity remains fairly unknown. In this study we investigated sleep structure and sleep electroencephalographic characteristics of 30 healthy young participants (16 men, 14 women; age range 20-31 years) following 2 h of evening light exposure to polychromatic light at 6500 K, 2500 K and 3000 K. Sleep structure across the first three non-rapid eye movement non-rapid eye movement – rapid eye movement sleep cycles did not differ significantly with respect to the light conditions. All-night non-rapid eye movement sleep electroencephalographic power density indicated that exposure to light at 6500 K resulted in a tendency for less frontal non-rapid eye movement electroencephalographic power density, compared to light at 2500 K and 3000 K. The dynamics of non-rapid eye movement electroencephalographic slow wave activity (2.0-4.0 Hz), a functional index of homeostatic sleep pressure, were such that slow wave activity was reduced significantly during the first sleep cycle after light at 6500 K compared to light at 2500 K and 3000 K, particularly in the frontal derivation. Our data suggest that exposure to blue-enriched polychromatic light at relatively low room light levels impacts upon homeostatic sleep regulation, as indexed by reduction in frontal slow wave activity during the first non-rapid eye movement episode.  
  Address Centre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel, Switzerland; Cyclotron Research Center, University of Liege, Liege, Belgium  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0962-1105 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23509952 Approved no  
  Call Number GFZ @ kyba @ Serial 2201  
Permanent link to this record
 

 
Author Walker, W.H. 2nd; Borniger, J.C.; Gaudier-Diaz, M.M.; Hecmarie Melendez-Fernandez, O.; Pascoe, J.L.; Courtney DeVries, A.; Nelson, R.J. url  doi
openurl 
  Title (up) Acute exposure to low-level light at night is sufficient to induce neurological changes and depressive-like behavior Type Journal Article
  Year 2019 Publication Molecular Psychiatry Abbreviated Journal Mol Psychiatry  
  Volume Issue Pages s41380-019-0430-4  
  Keywords Human health; physiology; brain  
  Abstract The advent and wide-spread adoption of electric lighting over the past century has profoundly affected the circadian organization of physiology and behavior for many individuals in industrialized nations; electric lighting in homes, work environments, and public areas have extended daytime activities into the evening, thus, increasing night-time exposure to light. Although initially assumed to be innocuous, chronic exposure to light at night (LAN) is now associated with increased incidence of cancer, metabolic disorders, and affective problems in humans. However, little is known about potential acute effects of LAN. To determine whether acute exposure to low-level LAN alters brain function, adult male, and female mice were housed in either light days and dark nights (LD; 14 h of 150 lux:10 h of 0 lux) or light days and low level light at night (LAN; 14 h of 150 lux:10 h of 5 lux). Mice exposed to LAN on three consecutive nights increased depressive-like responses compared to mice housed in dark nights. In addition, female mice exposed to LAN increased central tendency in the open field. LAN was associated with reduced hippocampal vascular endothelial growth factor-A (VEGF-A) in both male and female mice, as well as increased VEGFR1 and interleukin-1beta mRNA expression in females, and reduced brain derived neurotrophic factor mRNA in males. Further, LAN significantly altered circadian rhythms (activity and temperature) and circadian gene expression in female and male mice, respectively. Altogether, this study demonstrates that acute exposure to LAN alters brain physiology and can be detrimental to well-being in otherwise healthy individuals.  
  Address Department of Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, 26506, USA  
  Corporate Author Thesis  
  Publisher Nature Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1359-4184 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:31138889 Approved no  
  Call Number IDA @ john @ Serial 2509  
Permanent link to this record
 

 
Author Walker, W.H. 2nd; Borniger, J.C.; Gaudier-Diaz, M.M.; Hecmarie Melendez-Fernandez, O.; Pascoe, J.L.; Courtney DeVries, A.; Nelson, R.J. url  doi
openurl 
  Title (up) Acute exposure to low-level light at night is sufficient to induce neurological changes and depressive-like behavior Type Journal Article
  Year 2019 Publication Molecular Psychiatry Abbreviated Journal Mol Psychiatry  
  Volume Issue Pages s41380  
  Keywords Animals; mouse models; mood disorders; Human Health  
  Abstract The advent and wide-spread adoption of electric lighting over the past century has profoundly affected the circadian organization of physiology and behavior for many individuals in industrialized nations; electric lighting in homes, work environments, and public areas have extended daytime activities into the evening, thus, increasing night-time exposure to light. Although initially assumed to be innocuous, chronic exposure to light at night (LAN) is now associated with increased incidence of cancer, metabolic disorders, and affective problems in humans. However, little is known about potential acute effects of LAN. To determine whether acute exposure to low-level LAN alters brain function, adult male, and female mice were housed in either light days and dark nights (LD; 14 h of 150 lux:10 h of 0 lux) or light days and low level light at night (LAN; 14 h of 150 lux:10 h of 5 lux). Mice exposed to LAN on three consecutive nights increased depressive-like responses compared to mice housed in dark nights. In addition, female mice exposed to LAN increased central tendency in the open field. LAN was associated with reduced hippocampal vascular endothelial growth factor-A (VEGF-A) in both male and female mice, as well as increased VEGFR1 and interleukin-1beta mRNA expression in females, and reduced brain derived neurotrophic factor mRNA in males. Further, LAN significantly altered circadian rhythms (activity and temperature) and circadian gene expression in female and male mice, respectively. Altogether, this study demonstrates that acute exposure to LAN alters brain physiology and can be detrimental to well-being in otherwise healthy individuals.  
  Address Department of Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, 26506, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1359-4184 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:31138889; PMCID:PMC6881534 Approved no  
  Call Number GFZ @ kyba @ Serial 2768  
Permanent link to this record
 

 
Author Peixoto, C.A.T.; da Silva, A.G.T.; Carskadon, M.A.; Louzada, F.M. url  doi
openurl 
  Title (up) Adolescents living in homes without electric lighting have earlier sleep times Type Journal Article
  Year 2009 Publication Behavioral Sleep Medicine Abbreviated Journal Behav Sleep Med  
  Volume 7 Issue 2 Pages 73-80  
  Keywords Human Health; Sleep  
  Abstract The aim of this project was to compare circadian rhythmicity of a group of 37 adolescents (14 girls), aged 11 to 16 (mean age = 13.1 +/- 1.7 years), with and without electricity at home. Twenty students attended morning school (07:30-11:30), and 17 attended evening school classes (19:00-22:30). Eleven adolescents had no electric lighting at home (5 attended morning classes and 6 attended evening classes). They completed a sleep log and wore a wrist actigraph for 5 consecutive days. Saliva samples were collected to assess DLMO. Data were compared by ANOVA and showed later timing and a more extended sleep period for those who attended late classes. Those adolescents without electricity at home had significantly earlier sleep onset on school days. As to DLMO, a trend to a delay was observed in the groups who had electric lighting.  
  Address Department of Physiology, Universidade Federal do Parana, Brazil. pedatardelli@yahoo.com.br  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1540-2002 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:19330580 Approved no  
  Call Number LoNNe @ kyba @ Serial 1481  
Permanent link to this record
 

 
Author Stevens, R.G.; Brainard, G.C.; Blask, D.E.; Lockley, S.W.; Motta, M.E. url  doi
openurl 
  Title (up) Adverse health effects of nighttime lighting: comments on American Medical Association policy statement Type Journal Article
  Year 2013 Publication American Journal of Preventive Medicine Abbreviated Journal Am J Prev Med  
  Volume 45 Issue 3 Pages 343-346  
  Keywords American Medical Association; Cell Cycle/physiology; Circadian Rhythm/*physiology; DNA Damage/physiology; *Health Policy; Humans; Lighting/*adverse effects; United States  
  Abstract The American Medical Association House of Delegates in June of 2012 adopted a policy statement on nighttime lighting and human health. This major policy statement summarizes the scientific evidence that nighttime electric light can disrupt circadian rhythms in humans and documents the rapidly advancing understanding from basic science of how disruption of circadian rhythmicity affects aspects of physiology with direct links to human health, such as cell cycle regulation, DNA damage response, and metabolism. The human evidence is also accumulating, with the strongest epidemiologic support for a link of circadian disruption from light at night to breast cancer. There are practical implications of the basic and epidemiologic science in the form of advancing lighting technologies that better accommodate human circadian rhythmicity.  
  Address University of Connecticut Health Center, Farmington, Connecticut 06030-6325, USA. bugs@uchc.edu  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0749-3797 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23953362 Approved no  
  Call Number IDA @ john @ Serial 130  
Permanent link to this record
Select All    Deselect All
 |   | 
Details
   print

Save Citations:
Export Records: