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Author Lucas, R.J.; Peirson, S.N.; Berson, D.M.; Brown, T.M.; Cooper, H.M.; Czeisler, C.A.; Figueiro, M.G.; Gamlin, P.D.; Lockley, S.W.; O'Hagan, J.B.; Price, L.L.A.; Provencio, I.; Skene, D.J.; Brainard, G.C.
Title Measuring and using light in the melanopsin age Type Journal Article
Year 2014 Publication Trends in Neurosciences Abbreviated Journal Trends Neurosci
Volume 37 Issue 1 Pages 1-9
Keywords Editorial; Animals; Circadian Rhythm/physiology; Humans; Photoreceptor Cells/metabolism; Phototherapy/*trends; Retinal Ganglion Cells/metabolism; Rod Opsins/*physiology
Abstract Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In addition, light therapy is effective for certain affective disorders, sleep problems, and circadian rhythm disruption. These biological and behavioral effects of light are influenced by a distinct photoreceptor in the eye, melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs), in addition to conventional rods and cones. We summarize the neurophysiology of this newly described sensory pathway and consider implications for the measurement, production, and application of light. A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers.
Address Department of Neurology, Thomas Jefferson University, Philidelphia, PA, USA. Electronic address: George.Brainard@jefferson.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0166-2236 ISBN Medium
Area Expedition Conference
Notes PMID:24287308 Approved (up) no
Call Number LoNNe @ christopher.kyba @ Serial 457
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