toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
Details
   print
  Records Links
Author (up) Boyce, P.R. url  doi
openurl 
  Title Review: The Impact of Light in Buildings on Human Health Type Journal Article
  Year 2010 Publication Indoor and Built Environment Abbreviated Journal Indoor and Built Environment  
  Volume 19 Issue 1 Pages 8-20  
  Keywords Human Health; indoor light; circadian disruption; shift work; oncogenesis; Review  
  Abstract The effects of light on health can be divided into three sections. The first is that of light as radiation. Exposure to the ultraviolet, visible, and infrared radiation produced by light sources can damage both the eye and skin, through both thermal and photochemical mechanisms. Such damage is rare for indoor lighting installations designed for vision but can occur in some situations. The second is light operating through the visual system. Lighting enables us to see but lighting conditions that cause visual discomfort are likely to lead to eyestrain. Anyone who frequently experiences eyestrain is not enjoying the best of health. The lighting conditions that cause visual discomfort in buildings are well known and easily avoided. The third is light operating through the circadian system. This is known to influence sleep patterns and believed to be linked to the development of breast cancer among night shift workers. There is still much to learn about the impact of light on human health but what is known is enough to ensure that the topic requires the attention of all those concerned with the lighting of buildings.  
  Address Rensselaer Polytechnic Institute, New York, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1420-326X ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number IDA @ john @ Serial 292  
Permanent link to this record
 

 
Author (up) Brainard, G.C.; Coyle, W.; Ayers, M.; Kemp, J.; Warfield, B.; Maida, J.; Bowen, C.; Bernecker, C.; Lockley, S.W.; Hanifin, J.P. url  doi
openurl 
  Title Solid-state lighting for the International Space Station: Tests of visual performance and melatonin regulation Type Journal Article
  Year 2013 Publication Acta Astronautica Abbreviated Journal Acta Astronautica  
  Volume 92 Issue 1 Pages 21-28  
  Keywords Human Health; Lighting  
  Abstract The International Space Station (ISS) uses General Luminaire Assemblies (GLAs) that house fluorescent lamps for illuminating the astronauts' working and living environments. Solid-state light emitting diodes (LEDs) are attractive candidates for replacing the GLAs on the ISS. The advantages of LEDs over conventional fluorescent light sources include lower up-mass, power consumption and heat generation, as well as fewer toxic materials, greater resistance to damage and long lamp life. A prototype Solid-State Lighting Assembly (SSLA) was developed and successfully installed on the ISS. The broad aim of the ongoing work is to test light emitted by prototype SSLAs for supporting astronaut vision and assessing neuroendocrine, circadian, neurobehavioral and sleep effects. Three completed ground-based studies are presented here including experiments on visual performance, color discrimination, and acute plasma melatonin suppression in cohorts of healthy, human subjects under different SSLA light exposure conditions within a high-fidelity replica of the ISS Crew Quarters (CQ). All visual tests were done under indirect daylight at 201 lx, fluorescent room light at 531 lx and 4870 K SSLA light in the CQ at 1266 lx. Visual performance was assessed with numerical verification tests (NVT). NVT data show that there are no significant differences in score (F=0.73, p=0.48) or time (F=0.14, p=0.87) for subjects performing five contrast tests (10%–100%). Color discrimination was assessed with Farnsworth-Munsell 100 Hue tests (FM-100). The FM-100 data showed no significant differences (F=0.01, p=0.99) in color discrimination for indirect daylight, fluorescent room light and 4870 K SSLA light in the CQ. Plasma melatonin suppression data show that there are significant differences (F=29.61, p<0.0001) across the percent change scores of plasma melatonin for five corneal irradiances, ranging from 0 to 405 &#956;W/cm2 of 4870 K SSLA light in the CQ (0–1270 lx). Risk factors for the health and safety of astronauts include disturbed circadian rhythms and altered sleep–wake patterns. These studies will help determine if SSLA lighting can be used both to support astronaut vision and serve as an in-flight countermeasure for circadian desynchrony, sleep disruption and cognitive performance deficits on the ISS.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-5765 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ kyba @ Serial 1533  
Permanent link to this record
 

 
Author (up) Brainard, G.C.; Hanifin, J.P.; Greeson, J.M.; Byrne, B.; Glickman, G.; Gerner, E.; Rollag, M.D. url  openurl
  Title Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor. Type Journal Article
  Year 2001 Publication Journal of Neuroscience Abbreviated Journal  
  Volume 21 Issue Pages 6405-6412  
  Keywords Human Health  
  Abstract The photopigment in the human eye that transduces light for circadian and neuroendocrine regulation, is unknown. The aim of this study was to establish an action spectrum for light-induced melatonin suppression that could help elucidate the ocular photoreceptor system for regulating the human pineal gland. Subjects (37 females, 35 males, mean age of 24.5 ± 0.3 years) were healthy and had normal color vision. Full-field, monochromatic light exposures took place between 2:00 and 3:30 A.M. while subjects' pupils were dilated. Blood samples collected before and after light exposures were quantified for melatonin. Each subject was tested with at least seven different irradiances of one wavelength with a minimum of 1 week between each nighttime exposure. Nighttime melatonin suppression tests (n = 627) were completed with wavelengths from 420 to 600 nm. The data were fit to eight univariant, sigmoidal fluence–response curves (R 2 = 0.81–0.95). The action spectrum constructed from these data fit an opsin template (R 2 = 0.91), which identifies 446–477 nm as the most potent wavelength region providing circadian input for regulating melatonin secretion. The results suggest that, in humans, a single photopigment may be primarily responsible for melatonin suppression, and its peak absorbance appears to be distinct from that of rod and cone cell photopigments for vision. The data also suggest that this new photopigment is retinaldehyde based. These findings suggest that there is a novel opsin photopigment in the human eye that mediates circadian photoreception.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ christopher.kyba @ Serial 529  
Permanent link to this record
 

 
Author (up) Brainard, G.C.; Lewy, A.J.; Menaker, M.; Fredrickson, R.H.; Miller, L.S.; Weleber, R.G.; Cassone, V.; Hudson, D. url  doi
openurl 
  Title Effect of Light Wavelength on the Suppression of Nocturnal Plasma Melatonin in Normal Volunteersa Type Journal Article
  Year 1985 Publication Annals of the New York Academy of Sciences Abbreviated Journal  
  Volume 453 Issue 1 Pages 376-378  
  Keywords Human Health  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0077-8923 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ kagoburian @ Serial 723  
Permanent link to this record
 

 
Author (up) Brainard, G.C.; Rollag, M.D.; Hanifin, J.P. url  doi
openurl 
  Title Photic Regulation of Melatonin in Humans: Ocular and Neural Signal Transduction Type Journal Article
  Year 1997 Publication Journal of Biological Rhythms Abbreviated Journal Journal of Biological Rhythms  
  Volume 12 Issue 6 Pages 537-546  
  Keywords Human Health; eye; lens; light; melatonin suppression; photoreceptor; pineal gland; pupil  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0748-7304 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ schroer @ Serial 583  
Permanent link to this record
Select All    Deselect All
 |   | 
Details
   print

Save Citations:
Export Records: