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Author Srinivasan, V.; Spence, D.W.; Pandi-Perumal, S.R.; Trakht, I.; Esquifino, A.I.; Cardinali, D.P.; Maestroni, G.J. url  doi
openurl 
  Title Melatonin, environmental light, and breast cancer Type Journal Article
  Year 2008 Publication Breast Cancer Research and Treatment Abbreviated Journal (up) Breast Cancer Res Treat  
  Volume 108 Issue 3 Pages 339-350  
  Keywords Human Health; Breast Neoplasms/*etiology/*physiopathology; Circadian Rhythm/physiology; Female; Humans; Light; Lighting/*adverse effects; Melatonin/*physiology; Occupational Exposure/adverse effects  
  Abstract Although many factors have been suggested as causes for breast cancer, the increased incidence of the disease seen in women working in night shifts led to the hypothesis that the suppression of melatonin by light or melatonin deficiency plays a major role in cancer development. Studies on the 7,12-dimethylbenz[a]anthracene and N-methyl-N-nitrosourea experimental models of human breast cancer indicate that melatonin is effective in reducing cancer development. In vitro studies in MCF-7 human breast cancer cell line have shown that melatonin exerts its anticarcinogenic actions through a variety of mechanisms, and that it is most effective in estrogen receptor (ER) alpha-positive breast cancer cells. Melatonin suppresses ER gene, modulates several estrogen dependent regulatory proteins and pro-oncogenes, inhibits cell proliferation, and impairs the metastatic capacity of MCF-7 human breast cancer cells. The anticarcinogenic action on MCF-7 cells has been demonstrated at the physiological concentrations of melatonin attained at night, suggesting thereby that melatonin acts like an endogenous antiestrogen. Melatonin also decreases the formation of estrogens from androgens via aromatase inhibition. Circulating melatonin levels are abnormally low in ER-positive breast cancer patients thereby supporting the melatonin hypothesis for breast cancer in shift working women. It has been postulated that enhanced endogenous melatonin secretion is responsible for the beneficial effects of meditation as a form of psychosocial intervention that helps breast cancer patients.  
  Address Department of Physiology, School of Medical Sciences, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0167-6806 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:17541739 Approved no  
  Call Number LoNNe @ kagoburian @ Serial 815  
Permanent link to this record
 

 
Author Marchant, P.R. url  doi
openurl 
  Title A Demonstration That the Claim That Brighter Lighting Reduces Crime Is Unfounded Type Journal Article
  Year 2004 Publication British Journal of Criminology Abbreviated Journal (up) British Journal of Criminology  
  Volume 44 Issue 3 Pages 441-447  
  Keywords lighting; crime; street lighting  
  Abstract The major systematic review on street lighting and crime, Home Office Research Study 251, suggests that claims for the effectiveness of lighting against crime are justified. The review at first sight appears to be an appropriate statistical synthesis of all studies on street lighting and crime across the world. However on close examination, the statistical claims and methods are unfounded. In three cases examined there is a clear conflict between the evidence and the reviewers' interpretation of this. One of the principal problems is easily seen. The time-series of the original data from the Bristol study shows no good evidence for the crime reduction benefit of lighting. However the review gives the result for the same data as being extremely statistically significant. It is suggested that such a difference between the newly lit and the control areas occurring purely by chance is less than one in a billion, but this is manifestly wrong. Two other component studies, Birmingham and Dudley, are examined.  
  Address  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0007-0955 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number IDA @ john @ Serial 254  
Permanent link to this record
 

 
Author Cai, W.; Yue, J.; Dai, Q.; Hao, L.; Lin, Y.; Shi, W.; Huang, Y.; Wei, M. url  doi
openurl 
  Title The impact of room surface reflectance on corneal illuminance and rule-of-thumb equations for circadian lighting design Type Journal Article
  Year 2018 Publication Building and Environment Abbreviated Journal (up) Building and Environment  
  Volume 141 Issue Pages 288-297  
  Keywords Lighting  
  Abstract Recently, corneal illuminance attracts much attention because it is closely related to important functions of indoor lighting. Especially, applying circadian light in the built environment places a challenging requirement on indirect corneal illuminance. In this work, rule-of-thumb equations are proposed to guide circadian lighting design: (i) for artificial lighting, Ecor,avg (i) = (Φ/C1) · ρ/(1−ρ′), where Ecor,avg (i) is the average indirect corneal illuminance at standing or sitting positions, Φ is the initial flux from luminaires, C1 is a constant comparable to the total room surface area, ρ is the reflectance of the surface where the first reflection occurs, and ρ′ is the area-weighted average of surface reflectance; and (ii) for daylighting, Ecor,avg (i) = C2 · WWR · ρ/(1−ρ′), where C2 is a constant, and WWR represents the window-to-wall ratio.

The equations above are validated by comparing against numerical simulation data obtained with the Radiance software. For artificial lighting simulation, various combinations of room surface reflectance, initial light distribution, and WWR are investigated; and for daylighting simulation, different combinations of surface reflectance, WWR, and geographic location are analyzed. The good fits to simulation data indicate that the proposed simple equations can provide reasonably accurate results for quick feedback at the field. It is also demonstrated that room surface reflectance has a dominant impact on indirect corneal illuminance. The approach of improving surface reflectance is more favorable than increasing luminaire flux or expanding window area, and therefore should be the recommended approach to achieve quality and efficient circadian lighting.
 
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0360-1323 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 1929  
Permanent link to this record
 

 
Author Du, J.; Zhang, X.; King, D. url  doi
openurl 
  Title An investigation into the risk of night light pollution in a glazed office building: The effect of shading solutions Type Journal Article
  Year 2018 Publication Building and Environment Abbreviated Journal (up) Building and Environment  
  Volume 145 Issue Pages 243-259  
  Keywords Lighting; Planning  
  Abstract Light pollution has been recognised as a major environmental problem in urban areas at night. This study presents an investigation into the impact of seven various shading solutions on the risk of light pollution caused by indoor artificial lighting in a fully glazed office building. Radiance, a ray-tracing package, was adopted to calculate external illuminances produced by indoor lighting applications at various positions. It has been determined that: 1) A glazed façade could become a critical source of light pollution or obtrusive light (sky glow and light trespass) due to applications of indoor lighting at night; 2) A light shelf could perform well on the protection of both light trespass and sky glow; 3) A large overhang and horizontal louvre could effectively lower the risk of light trespass, but would possibly cause the deterioration of sky glow; and 4) No significant impact of short overhang and vertical louvre can be found on the two aspects of light pollution. This study exposes a significant implication; apart from their principal functions, the shading devices applied in a largely glazed building may require a new role in controlling obtrusive light in cities at night.  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0360-1323 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2015  
Permanent link to this record
 

 
Author Boyce, P.R. url  doi
openurl 
  Title The benefits of light at night Type Journal Article
  Year 2019 Publication Building and Environment Abbreviated Journal (up) Building and Environment  
  Volume 151 Issue Pages 356-367  
  Keywords Lighting; Society; Conservation  
  Abstract The use of light at night continues to increase. Simply put, this is because without light we are deprived of our premier sense, vision. By enabling vision the use of light at night delivers a number of benefits to people. Such benefits include greater safety for pedestrians and drivers, reduced fear of crime, more use of outdoor facilities after dark, enhanced economic growth and the creation of built and natural environments that are a source of beauty and entertainment. This suggests that the use of light at night is linked to some very basic human motivations which in turn means that people value such benefits and will not willingly abandon them. Fortunately, careful lighting design, soundly-based outdoor lighting standards and new lighting and sensor technology offer the possibility of providing the benefits of light at night while minimizing the impact on the environment.  
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  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0360-1323 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2171  
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