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Author (up) Bullough, J.D.; Bierman, A.; Rea, M.S.
Title Evaluating the Blue-Light Hazard from Solid State Lighting Type Journal Article
Year 2017 Publication International Journal of Occupational Safety and Ergonomics : JOSE Abbreviated Journal Int J Occup Saf Ergon
Volume 25 Issue 2 Pages 311-320
Keywords Human Health
Abstract Purpose New light sources including light emitting diodes (LEDs) have elicited questions about retinal damage, including the blue-light hazard. Some organizations have recommended avoiding using LEDs with correlated color temperatures (CCTs) exceeding 3000 K, since they tend to produce greater short-wavelength energy. This paper provides quantitative comparisons among light sources and use cases as they affect blue-light hazard. Methods The spectral radiant power characteristics of incandescent, fluorescent, LED and daylight sources were evaluated in terms of blue-light hazard using standard procedures for phakic, aphakic and pseudophakic eyes. Results Under most use cases, LEDs do not exhibit greater risk for blue-light hazard than other sources (e.g., incandescent). Because they generally produce little-to-no ultraviolet energy, LEDs often present less risk to aphakic eyes. Conclusions LEDs present no special concerns for blue-light hazard over some other common sources in typical use cases because photophobic responses limit exposure to bright sources. Where photophobic responses might not occur (e.g., eye surgery patients or premature infants) or where individuals suppress these responses (e.g., stage actors), caution is necessary. Evidence remains inconsistent regarding the risk of human retinal damage from long-term exposures to light insufficient to reach acute blue-light hazard thresholds.
Address a Lighting Research Center , Rensselaer Polytechnic Institute , US
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Language English Summary Language Original Title
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Series Volume Series Issue Edition
ISSN 1080-3548 ISBN Medium
Area Expedition Conference
Notes PMID:28876164 Approved no
Call Number LoNNe @ kyba @; GFZ @ kyba @ Serial 1720
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Author (up) Bumgarner, J.R.; Walker, W.H. 2nd; Liu, J.A.; Walton, J.C.; Nelson, R.J.
Title Dim light at night exposure induces cold hyperalgesia and mechanical allodynia in male mice Type Journal Article
Year 2020 Publication Neuroscience Abbreviated Journal Neuroscience
Volume in press Issue Pages
Keywords Animals; Allodynia; Hyperalgesia; Light at Night; Neuroinflammation; Opioid; Pain
Abstract The growing presence of artificial lighting across the globe presents a number of challenges to human and ecological health despite its societal benefits. Exposure to artificial light at night, a seemingly innocuous aspect of modern life, disrupts behavior and physiological functions. Specifically, light at night induces neuroinflammation, which is implicated in neuropathic and nociceptive pain states, including hyperalgesia and allodynia. Because of its influence on neuroinflammation, we investigated the effects of dim light at night exposure on pain responsiveness in male mice. In this study, mice exposed to four days of dim (5 lux) light at night exhibited cold hyperalgesia. Further, after 28 days of exposure, mice exhibited both cold hyperalgesia and mechanical allodynia. No heat/hot hyperalgesia was observed in this experiment. Altered nociception in mice exposed to dim light at night was concurrent with upregulated interleukin-6 and nerve growth factor mRNA expression in the medulla and elevated mu-opioid receptor mRNA expression in the periaqueductal gray region of the brain. The current results support the relationship between disrupted circadian rhythms and altered pain sensitivity. In summary, we observed that dim light at night induces cold hyperalgesia and mechanical allodynia, potentially through elevated central neuroinflammation and dysregulation of the endogenous opioid system.
Address Department of Neuroscience, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, 26506 United States
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Language English Summary Language Original Title
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Series Volume Series Issue Edition
ISSN 0306-4522 ISBN Medium
Area Expedition Conference
Notes PMID:32201267 Approved no
Call Number GFZ @ kyba @ Serial 2864
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Author (up) Buonfiglio, D.; Parthimos, R.; Dantas, R.; Cerqueira Silva, R.; Gomes, G.; Andrade-Silva, J.; Ramos-Lobo, A.; Amaral, F.G.; Matos, R.; Sinesio, J.J.; Motta-Teixeira, L.C.; Donato, J.J.; Reiter, R.J.; Cipolla-Neto, J.
Title Melatonin Absence Leads to Long-Term Leptin Resistance and Overweight in Rats Type Journal Article
Year 2018 Publication Frontiers in Endocrinology Abbreviated Journal Front Endocrinol (Lausanne)
Volume 9 Issue Pages 122
Keywords Human health
Abstract Melatonin (Mel), a molecule that conveys photoperiodic information to the organisms, is also involved in the regulation of energy homeostasis. Mechanisms of action of Mel in the energy balance remain unclear; herein we investigated how Mel regulates energy intake and expenditure to promote a proper energy balance. Male Wistar rats were assigned to control, control + Mel, pinealectomized (PINX) and PINX + Mel groups. To restore a 24-h rhythm, Mel (1 mg/kg) was added to the drinking water exclusively during the dark phase for 13 weeks. After this treatment period, rats were subjected to a 24-h fasting test, an acute leptin responsiveness test and cold challenge. Mel treatment reduced food intake, body weight, and adiposity. When challenged to 24-h fasting, Mel-treated rats also showed reduced hyperphagia when the food was replaced. Remarkably, PINX rats exhibited leptin resistance; this was likely related to the capacity of leptin to affect body weight, food intake, and hypothalamic signal-transducer and activator of transcription 3 phosphorylation, all of which were reduced. Mel treatment restored leptin sensitivity in PINX rats. An increased hypothalamic expression of agouti-related peptide (Agrp), neuropeptide Y, and Orexin was observed in the PINX group while Mel treatment reduced the expression of Agrp and Orexin. In addition, PINX rats presented lower UCP1 protein levels in the brown adipose tissue and required higher tail vasoconstriction to get a proper thermogenic response to cold challenge. Our findings reveal a previously unrecognized interaction of Mel and leptin in the hypothalamus to regulate the energy balance. These findings may help to explain the high incidence of metabolic diseases in individuals exposed to light at night.
Address Department of Physiology and Biophysics, Institute of Biomedical Sciences-I, University of Sao Paulo (USP), Sao Paulo, Brazil
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Language English Summary Language Original Title
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Series Volume Series Issue Edition
ISSN 1664-2392 ISBN Medium
Area Expedition Conference
Notes PMID:29636725; PMCID:PMC5881424 Approved no
Call Number NC @ ehyde3 @ Serial 2093
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Author (up) Burger, J.W.
Title Some aspects of the roles of light intensity and the daily length of exposure to light in the sexual photoperiodic activation of the male starling Type Journal Article
Year 1939 Publication Journal of Experimental Zoology Abbreviated Journal J. Exp. Zool.
Volume 81 Issue 3 Pages 333-341
Keywords Animals
Abstract
Address
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Language Summary Language Original Title
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ISSN 0022-104X ISBN Medium
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Notes Approved no
Call Number GFZ @ kyba @ Serial 2394
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Author (up) Burggraaff, O., Schmidt, N., Zamorano, J., Pauly, K., Pascual, S., Tapia, C., Spyrakos, E., & Snik, F.
Title Standardized spectral and radiometric calibration of consumer cameras Type Journal Article
Year 2019 Publication Optical Express Abbreviated Journal
Volume 27 Issue 14 Pages 19075-19101
Keywords Instrumentation
Abstract Consumer cameras, particularly onboard smartphones and UAVs, are now commonly used as scientific instruments. However, their data processing pipelines are not optimized for quantitative radiometry and their calibration is more complex than that of scientific cameras. The lack of a standardized calibration methodology limits the interoperability between devices and, in the ever-changing market, ultimately the lifespan of projects using them. We present a standardized methodology and database (SPECTACLE) for spectral and radiometric calibrations of consumer cameras, including linearity, bias variations, read-out noise, dark current, ISO speed and gain, flat-field, and RGB spectral response. This includes golden standard ground-truth methods and do-it-yourself methods suitable for non-experts. Applying this methodology to seven popular cameras, we found high linearity in RAW but not JPEG data, inter-pixel gain variations >400% correlated with large-scale bias and read-out noise patterns, non-trivial ISO speed normalization functions, flat-field correction factors varying by up to 2.79 over the field of view, and both similarities and differences in spectral response. Moreover, these results differed wildly between camera models, highlighting the importance of standardization and a centralized database.
Address
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Notes Approved no
Call Number IDA @ intern @ Serial 2652
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