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Author Torres-Farfan, C.; Mendez, N.; Ehrefeld, P.; Seron-Ferre, M. url  doi
openurl 
  Title In utero circadian changes; facing light pollution Type Journal Article
  Year 2019 Publication Current Opinion in Physiology Abbreviated Journal Current Opinion in Physiology  
  Volume Issue Pages in press  
  Keywords Review; Human Health  
  Abstract Regardless of the molecular and physiological mechanisms involved, maternal fetal circadian systems interactions are recognized as crucial crosstalk for fetal development, and in turn, it may be a key factor determining fitting health in adulthood.

However, in the last 100 years, life on the planet has altered the natural light-dark cycle by increasing light at night inducing disorganization of the circadian system, i.e. chronodisruption, including perturbation of the melatonin circadian rhythm by decreasing its nocturnal peak. The reduction in melatonin is associated with gradual losses in antioxidant protection, immunological and anti-inflammatory effects and as stated by WHO, the lack of nocturnal peak of melatonin is a deleterious signal that may induce chronic disease and cancer.

Collectively the current review provides evidence about the role played by maternal circadian rhythms in fetal development and the impact of fetal-maternal desynchronization in the health and diseases of the offspring.
 
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  ISSN (down) 2468-8673 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2761  
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Author Wang, H.-B.; Whittaker, D.S.; Truong, D.; Mulji, A.K.; Ghiani, C.A.; Loh, D.H.; Colwell, C.S. url  doi
openurl 
  Title Blue light therapy improves circadian dysfunction as well as motor symptoms in two mouse models of Huntington's disease Type Journal Article
  Year 2017 Publication Neurobiology of Sleep and Circadian Rhythms Abbreviated Journal Neurobiology of Sleep and Circadian Rhythms  
  Volume 2 Issue Pages 39-52  
  Keywords animals; Human Health  
  Abstract Patients with Huntington's disease (HD) exhibit movement disorders, psychiatric disturbance and cognitive impairments as the disease progresses. Abnormal sleep/wake cycles are common among HD patients with reports of delayed sleep onset, fatigue during the day, and a delayed pattern of melatonin secretion all of which suggest circadian dysfunction. Mouse models of HD confirm disrupted circadian rhythms with pathophysiology found in the central circadian clock (suprachiasmatic nucleus). Importantly, circadian dysfunction manifests early in disease, even before the classic motor symptoms, in both patients and mouse models. Therefore, we hypothesize that the circadian dysfunction may interact with the disease pathology and exacerbate the HD symptoms. If correct, early intervention may benefit patients and delay disease progression. One test of this hypothesis is to determine whether light therapy designed to strengthen this intrinsic timing system can delay the disease progression in mouse models. Therefore, we determined the impact of blue wavelength-enriched light on two HD models: the BACHD and Q175 mice. Both models received 6 hours of blue-light at the beginning of their daily light cycle for 3 months. After treatment, both genotypes showed improvements in their locomotor activity rhythm without significant change to their sleep behavior. Critically, treated mice of both lines exhibited improved motor performance compared to untreated controls. Focusing on the Q175 genotype, we sought to determine whether the treatment altered signaling pathways in brain regions known to be impacted by HD using NanoString gene expression assays. We found that the expression of several HD relevant markers was altered in the striatum and cortex of the treated mice. Our study demonstrates that strengthening the circadian system can delay the progression of HD in pre-clinical models. This work suggests that lighting conditions should be considered when managing treatment of HD and other neurodegenerative disorders.  
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  Series Volume Series Issue Edition  
  ISSN (down) 2451-9944 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ kyba @ Serial 1626  
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Author Checa, J.; Nel·lo, O. url  doi
openurl 
  Title Urban Intensities. The Urbanization of the Iberian Mediterranean Coast in the Light of Nighttime Satellite Images of the Earth Type Journal Article
  Year 2018 Publication Urban Science Abbreviated Journal Urban Science  
  Volume 2 Issue 4 Pages 115  
  Keywords Remote Sensing; Tourism  
  Abstract The contribution shares the approach of critical urban studies that have conceptualized urbanization more as a process than as a sum of spatial forms. Thus, the contribution studies the urbanization process not only from the point of view of the physical occupation of land but also considers changes in the intensity of the uses of space. To fulfill this aim, the new sources of nocturnal satellite images are particularly useful. These allow us to observe the intensity of urban uses both in terms of their distribution over space and their recurrence over time. The research focuses on the Iberian Mediterranean coast and permits the verification of the intensity of the urban uses of the space for the whole of this area and their seasonal variations throughout the year. The source of the study are the nighttime satellite images of the Earth for the 2012–2017 period from the NASA SNPP satellite equipped with the VIIRS-DNB instrument. By establishing a threshold of urban light the research shows that those districts with the greatest extensions of urban light do not necessarily correspond with the most densely populated areas. Similarly the absence of urban light does not necessarily indicate the absence of urban uses. Finally, the variations of intensity of light prove to be a good indicator of seasonal variations of activity in tourist areas.  
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  Series Volume Series Issue Edition  
  ISSN (down) 2413-8851 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2120  
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Author Bagan, H.; Borjigin, H.; Yamagata, Y. url  doi
openurl 
  Title Assessing nighttime lights for mapping the urban areas of 50 cities across the globe Type Journal Article
  Year 2018 Publication Environment and Planning B: Urban Analytics and City Science Abbreviated Journal Environment and Planning B: Urban Analytics and City Science  
  Volume Issue Pages 2399808317752926  
  Keywords Remote Sensing  
  Abstract Nighttime data from the Defense Meteorological Satellite Program Operational Linescan System have been widely used to map urban/built-up areas (hereafter referred to as “built-up area”), but to date there has not been a geographically comprehensive evaluation of the effectiveness of using nighttime lights data to map urban areas. We created accurate, convenient, and scalable grid cells based on Defense Meteorological Satellite Program/Operational Linescan System nighttime light pixels. We then calculated the density of Landsat-derived built-up areas within each grid cell. We explored the relationship between Defense Meteorological Satellite Program/Operational Linescan System nighttime lights data and the density of built-up areas to assess the utility of nighttime lights for mapping urban areas in 50 cities across the globe. We found that the brightness of nighttime lights was only in moderate agreement with the density of built-up areas; moreover, correlations between nighttime lights and Landsat-derived built-up areas were weak. Even in relatively sparsely populated urban regions (where the density of the built-up area is less than 20%), the highest correlation coefficient (R2) was only 0.4. Furthermore, nighttime lights showed lighted areas that extended beyond the area of large cities, and nighttime lights reduced the area of small cities. The results suggest that it is difficult to use the regression model to calibrate the Defense Meteorological Satellite Program/Operational Linescan System nighttime lights to fit urban built up areas.  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (down) 2399-8083 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ kyba @; GFZ @ kyba @ Serial 1795  
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Author Li, X.; Duarte, F.; Ratti, C. url  doi
openurl 
  Title Analyzing the obstruction effects of obstacles on light pollution caused by street lighting system in Cambridge, Massachusetts Type Journal Article
  Year 2019 Publication Environment and Planning B: Urban Analytics and City Science Abbreviated Journal Environment and Planning B: Urban Analytics and City Science  
  Volume in press Issue Pages  
  Keywords Skyglow; Lighting  
  Abstract Artificial light has transformed urban life, enhancing visibility, aesthetics, and increasing safety in public areas. However, too much unwanted artificial light leads to light pollution, which has a negative effect on public health and urban ecosystems, as well as on the aesthetic and cultural meanings of the night sky. Some of the factors interfering with the estimation of light pollution in cities are urban features, such as the presence of trees, road dimensions, and the physical characteristics of buildings. In this study, we proposed a simplified model for unwanted upward light coming from street luminaires based on a building height model and the publicly accessible Google Street View images. We simulated and analyzed the obstruction effects of different street features on the light pollution caused by the street lighting system in Cambridge, Massachusetts. By providing quantitative information about the connections between the streetscape features and the amount of unwanted upward artificial light, this study provides reference values to inform policies aimed at curbing light pollution.  
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  Corporate Author Thesis  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (down) 2399-8083 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2587  
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