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Author Boswell, W.T.; Boswell, M.; Walter, D.J.; Navarro, K.L.; Chang, J.; Lu, Y.; Savage, M.G.; Shen, J.; Walter, R.B. url  doi
openurl 
  Title Exposure to 4100K fluorescent light elicits sex specific transcriptional responses in Xiphophorus maculatus skin Type Journal Article
  Year 2018 Publication Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP Abbreviated Journal Comp Biochem Physiol C Toxicol Pharmacol  
  Volume 208 Issue Pages 96-104  
  Keywords Animals  
  Abstract It has been reported that exposure to artificial light may affect oxygen intake, heart rate, absorption of vitamins and minerals, and behavioral responses in humans. We have reported specific gene expression responses in the skin of Xiphophorus fish after exposure to ultraviolet light (UV), as well as, both broad spectrum and narrow waveband visible light. In regard to fluorescent light (FL), we have shown that male X. maculatus exposed to 4100K FL (i.e. “cool white”) rapidly suppress transcription of many genes involved with DNA replication and repair, chromosomal segregation, and cell cycle progression in skin. We have also detailed sex specific transcriptional responses of Xiphophorus skin after exposure to UVB. However, investigation of gender differences in global gene expression response after exposure to 4100K FL has not been reported, despite common use of this FL source for residential, commercial, and animal facility illumination. Here, we compare RNASeq results analyzed to assess changes in the global transcription profiles of female and male X. maculatus skin in response to 4100K FL exposure. Our results suggest 4100K FL exposure incites a sex-biased genetic response including up-modulation of inflammation in females and down modulation of DNA repair/replication in males. In addition, we identify clusters of genes that become oppositely modulated in males and females after FL exposure that are principally involved in cell death and cell proliferation.  
  Address Department of Chemistry and Biochemistry, Xiphophorus Genetic Stock Center, Texas State University, 601 University Drive, San Marcos, TX 78666, USA. Electronic address: RW12@txstate.edu  
  Corporate Author Thesis  
  Publisher Place of Publication (up) Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1532-0456 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28965926 Approved no  
  Call Number LoNNe @ kyba @ Serial 1739  
Permanent link to this record
 

 
Author Gonzalez, T.J.; Lu, Y.; Boswell, M.; Boswell, W.; Medrano, G.; Walter, S.; Ellis, S.; Savage, M.; Varga, Z.M.; Lawrence, C.; Sanders, G.; Walter, R.B. url  doi
openurl 
  Title Fluorescent light exposure incites acute and prolonged immune responses in Zebrafish (Danio rerio) skin Type Journal Article
  Year 2018 Publication Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP Abbreviated Journal Comp Biochem Physiol C Toxicol Pharmacol  
  Volume 208 Issue Pages 87-95  
  Keywords Animals  
  Abstract Artificial light produces an emission spectrum that is considerably different than the solar spectrum. Artificial light has been shown to affect various behavior and physiological processes in vertebrates. However, there exists a paucity of data regarding the molecular genetic effects of artificial light exposure. Previous studies showed that one of the commonly used fluorescent light source (FL; 4100K or “cool white”) can affect signaling pathways related to maintenance of circadian rhythm, cell cycle progression, chromosome segregation, and DNA repair/recombination in the skin of male Xiphophorus maculatus. These observations raise questions concerning the kinetics of the FL induced gene expression response, and which biological functions become modulated at various times after light exposure. To address these questions, we exposed zebrafish to 4100K FL and utilized RNASeq to assess gene expression changes in skin at various times (1 to 12h) after FL exposure. We found 4100K FL incites a robust early (1-2h) transcriptional response, followed by a more protracted late response (i.e., 4-12h). The early transcriptional response involves genes associated with cell migration/infiltration and cell proliferation as part of an overall increase in immune function and inflammation. The protracted late transcriptional response occurs within gene sets predicted to maintain and perpetuate the inflammatory response, as well as suppression of lipid, xenobiotic, and melatonin metabolism.  
  Address Xiphophorus Genetic Stock Center, Department of Chemistry and Biochemistry, 419 Centennial Hall, Texas State University, 601 University Drive, San Marcos, TX 78666, USA. Electronic address: RWalter@txstate.edu  
  Corporate Author Thesis  
  Publisher Place of Publication (up) Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1532-0456 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28965927 Approved no  
  Call Number LoNNe @ kyba @ Serial 1740  
Permanent link to this record
 

 
Author Van Doren, B.; Horton, K.G.; Dokter, A.M.; Klinck, H.; Elbin, S.B., Farnsworth, A.; Dokter, A.M; Klinck, H.; Elbin, S.B.; Farnsworth, A. url  doi
openurl 
  Title High-intensity urban light installation dramatically alters nocturnal bird migration Type Journal Article
  Year 2017 Publication Publications of the National Academy of Sciences Abbreviated Journal PNAS  
  Volume 114 Issue 42 Pages 11175-11180  
  Keywords Animals; artificial light; nocturnal migration; remote sensing; radar; ornithology; flight calls  
  Abstract Billions of nocturnally migrating birds move through increasingly photopolluted skies, relying on cues for navigation and orientation that artificial light at night (ALAN) can impair. However, no studies have quantified avian responses to powerful ground-based light sources in urban areas. We studied effects of ALAN on migrating birds by monitoring the beams of the National September 11 Memorial & Museum's “Tribute in Light” in New York, quantifying behavioral responses with radar and acoustic sensors and modeling disorientation and attraction with simulations. This single light source induced significant behavioral alterations in birds, even in good visibility conditions, in this heavily photopolluted environment, and to altitudes up to 4 km. We estimate that the installation influenced ≈1.1 million birds during our study period of 7 d over 7 y. When the installation was illuminated, birds aggregated in high densities, decreased flight speeds, followed circular flight paths, and vocalized frequently. Simulations revealed a high probability of disorientation and subsequent attraction for nearby birds, and bird densities near the installation exceeded magnitudes 20 times greater than surrounding baseline densities during each year’s observations. However, behavioral disruptions disappeared when lights were extinguished, suggesting that selective removal of light during nights with substantial bird migration is a viable strategy for minimizing potentially fatal interactions among ALAN, structures, and birds. Our results also highlight the value of additional studies describing behavioral patterns of nocturnally migrating birds in powerful lights in urban areas as well as conservation implications for such lighting installations.  
  Address Information Science Program, Cornell Lab of Ornithology, Ithaca, NY 14850 USA; af27{at}cornell.edu  
  Corporate Author Thesis  
  Publisher PNAS Place of Publication (up) Editor  
  Language English Summary Language English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1091-6490 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number IDA @ john @ Serial 1741  
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Author Alessandro Manfrin, Gabriel Singer, Stefano Larsen, Nadine Weiss, Roy H. A. van Grunsven, Nina-Sophie Weiss, Stefanie Wohlfahrt, Michael T. Monaghan and Franz Hölker url  doi
openurl 
  Title Artificial light at night affects organism flux across ecosystem boundaries and drives community structure in the recipient ecosystem Type Journal Article
  Year 2017 Publication Frontiers in Environmental Science Abbreviated Journal  
  Volume 5 Issue 61 Pages  
  Keywords Animals; Ecology  
  Abstract Artificial light at night (ALAN) is a widespread alteration of the natural environment that can affect the functioning of ecosystems. ALAN can change the movement patterns of freshwater animals that move into the adjacent riparian and terrestrial ecosystems, but the implications for local riparian consumers that rely on these subsidies are still unexplored. We conducted a two-year field experiment to quantify changes of freshwater-terrestrial linkages by installing streetlights in a previously light-native riparian area adjacent to an agricultural drainage ditch. We compared the abundance and community composition of emerging aquatic insects, flying insects, and ground-dwelling arthropods with an unlit control site. Comparisons were made within and between years using generalized least squares and a BACI design (Before-After Control-Impact). Aquatic insect emergence, the proportion of flying insects that were aquatic in origin, and the total abundance of flying insects all increased in the ALAN-illuminated area. The abundance of several night-active ground-dwelling predators (Pachygnatha clercki, Trochosa sp., Opiliones) increased under ALAN and their activity was extended into the day. Conversely, the abundance of nocturnal ground beetles (Carabidae) decreased under ALAN. The changes in composition of riparian predator and scavenger communities suggest that the increase in aquatic-to-terrestrial subsidy flux may cascade through the riparian food web. The work is among the first studies to experimentally manipulate ALAN using a large-scale field experiment, and provides evidence that ALAN can affect processes that link adjacent ecosystems. Given the large number of streetlights that are installed along shorelines of freshwater bodies throughout the globe, the effects could be widespread and represent an underestimated source of impairment for both aquatic and riparian systems.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication (up) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ kyba @ Serial 1746  
Permanent link to this record
 

 
Author Albreiki, Mohammed S. url  openurl
  Title The effects of light at night and/or melatonin on hormones, metabo- lites, appetite control, vascular function, and behavioural responses. Type Journal Article
  Year 2017 Publication University of Surrey Abbreviated Journal  
  Volume Issue Pages  
  Keywords Human Health  
  Abstract Light at night (LAN) is a major factor in disruption of SCN function, including melatonin suppression. Melatonin has been linked to a variety of biological processes such as lipid and glucose metabolism, vascular parameters, appetite, and behaviour. However, few human studies have investigated the effect of LAN and suppressed melatonin prior to and after an evening meal. The current thesis aims to investigate the impact of light at night and/or mela- tonin on hormones, metabolites, appetite, vascular function, and behaviour prior to and after an evening test meal in healthy participants. The first study investigated the effect of dim or bright light conditions on hor- mones, metabolites, appetite, vascular function and behavioural responses. Glucose tolerance and insulin sensitivity were reduced, lipid profiles altered and salivary melatonin suppressed under bright light compared to dim light conditions. Subjec- tive mood was improved and appetite scores increased in bright light. No differences were seen in vascular parameters. Although clear differences were apparent it could not be determined whether the effects were due to the light at night, the absence of melatonin or a combination of the two. The second study involved three conditions with the administration of exogenous melatonin 90 mins before the evening test meal under bright and dim light conditions compared to bright light alone with the consequent melatonin suppression. Glucose tolerance and insulin sensitivity were reduced and lipid profile altered in bright light when melatonin was suppressed compared to the two conditions with exogenous melatonin. Mood was improved and appetite increased with lower leptin levels and elevated wrist temperature with bright light and suppressed melatonin. Statistical analysis showed that the major effects were due to melatonin. These studies demonstrate a possible role for melatonin in glucose tolerance, insulin sensitivity and lipid metabolism when eating late at night which may have implications for shift-workers.  
  Address  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Place of Publication (up) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ kyba @; GFZ @ kyba @ Serial 1747  
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