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Author Esaki, Y.; Obayashi, K.; Saeki, K.; Fujita, K.; Iwata, N.; Kitajima, T.
Title Association between light exposure at night and manic symptoms in bipolar disorder: cross-sectional analysis of the APPLE cohort Type Journal Article
Year 2020 Publication (up) Chronobiology International Abbreviated Journal Chronobiol Int
Volume in press Issue Pages in press
Keywords Human Health; Bipolar disorder; circadian rhythm; dark; light at night; manic symptom
Abstract Previous studies have found that keeping the room dark at night was associated with a decrease in manic symptoms for patients with bipolar disorder (BD). However, the association between light at night of real-life conditions and manic symptoms is unclear. We investigated the association between bedroom light exposure at night and manic symptoms in BD patients. One-hundred and eighty-four outpatients with BD participated in this cross-sectional study. The average light intensity at night during sleep was evaluated using a portable photometer for seven consecutive nights. Manic symptoms were assessed using the Young Mania Rating Scale (YMRS), and scores >/=5 were treated as a “hypomanic state.” The median (interquartile range) YMRS score was 2.0 (0-5.0), and 52 (28.2%) participants were in a hypomanic state. The prevalence of a hypomanic state was significantly higher in the participants with an average light intensity at night exposure of >/=3 lux than in those with <3 lux (36.7% versus 21.9%; P = .02). In multivariable logistic regression analysis adjusted for BD type, depressive symptoms, sleep duration, and daytime physical activity, the odds ratio (OR) for a hypomanic state was significantly higher for the participants with an average light intensity at night exposure of >/=3 lux than for those with <3 lux (OR: 2.15, 95% confidence interval: 1.09-4.22, P = .02). This association remained significant at the cutoff value of YMRS score >/=6 (OR: 2.51, 95% confidence interval: 1.15-5.46; P = .02). The findings of this study indicate bedroom light exposure at night is significantly associated with manic symptoms in BD patients. Although the results of this cross-sectional investigation do not necessarily imply causality, they may serve to inform beneficial nonpharmacological intervention and personalized treatment of BD patients.
Address Department of Psychiatry, Fujita Health University School of Medicine, Aichi, Japan
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0742-0528 ISBN Medium
Area Expedition Conference
Notes PMID:32238002 Approved no
Call Number GFZ @ kyba @ Serial 2924
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Author Bagci, S.; Sabir, H.; Muller, A.; Reiter, R.J.
Title Effects of altered photoperiod due to COVID-19 lockdown on pregnant women and their fetuses Type Journal Article
Year 2020 Publication (up) Chronobiology International Abbreviated Journal Chronobiol Int
Volume in press Issue Pages in press
Keywords Human Health; Covid-19; circadian disruption; fetus; lockdown; melatonin; pregnant Women
Abstract Maternal circadian rhythms provide highly important input into the entrainment and programming of fetal and newborn circadian rhythms. The light-dark cycle is an important regulator of the internal biological clock. Even though pregnant women spend a greater part of the day at home during the latter stages of pregnancy, natural light exposure is crucial for the fetus. The current recommended COVID-19 lockdown might dramatically alter normal environmental lighting conditions of pregnant women, resulting in exposure to extremely low levels of natural daylight and high-intensity artificial light sources during both day and night. This article summarizes the potential effects on pregnant woman and their fetuses due to prolonged exposure to altered photoperiod and as consequence altered circadian system, known as chronodisruption, that may result from the COVID-19 lockdown.
Address Department of Cell Systems and Anatomy, UT Health San Antonio , San Antonio, Texas, USA
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0742-0528 ISBN Medium
Area Expedition Conference
Notes PMID:32519912 Approved no
Call Number GFZ @ kyba @ Serial 3007
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Author Calvo-Sanz, J.A.; Tapia-Ayuga, C.E.
Title Blue light emission spectra of popular mobile devices: The extent of user protection against melatonin suppression by built-in screen technology and light filtering software systems Type Journal Article
Year 2020 Publication (up) Chronobiology International Abbreviated Journal Chronobiol Int
Volume Issue Pages 1-7
Keywords Measurements; Blue light; blue light emission; light control software; mobile devices; screen technology
Abstract Blue light, with wavelengths shorter than 440-450 nm, is the most energetic radiation of the visible spectrum for the human eye, and its possible multiple effects on the human nervous and other systems have become a line of research by many investigators. The use of mobile devices whose screens emit various amounts of blue light is common nowadays. This study evaluated the efficiency of the blue light screen and control software technologies of eight different mobile devices. Emitted screen spectra of the different mobile devices according to different conditions of blue light emission software control were obtained using a spectrograph, and the derived spectra were compared with the melatonin suppression action spectrum. The amount of blue light emission and predicted melatonin suppression varied according to the unique software control and screen technology of each device. AMOLED screen technology, compared with other screen technologies, achieved better control of blue light emission. The effect of blue light filters depends on the screen technology; however, the melatonin suppression index of mobile devices is not reduced sufficiently by the use of blue light-attenuating software.
Address Departamento De Fisica De La Atmosfera Y Astrofisica, Universidad Complutense De Madrid , Madrid, Spain
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0742-0528 ISBN Medium
Area Expedition Conference
Notes PMID:32649241 Approved no
Call Number IDA @ john @ Serial 3048
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Author Liu, Y.; Zhang, X.; Pan, X.; Ma, X.; Tang, M.
Title The spatial integration and coordinated industrial development of urban agglomerations in the Yangtze River Economic Belt, China Type Journal Article
Year 2020 Publication (up) Cities Abbreviated Journal Cities
Volume 104 Issue Pages 102801
Keywords Remote Sensing
Abstract Urban agglomeration is the engine of national development and regional prosperity. Although extensive work has investigated issues related to this new form of spatial governance, few studies have directly illustrated the spatial integration of urban agglomeration and its relationship with industrial development. This paper employs nighttime light data and industrial enterprise datasets to investigate the spatial integration and industrial development in the Yangtze River Economic Belt (YREB) of China for 1995–2015. We here illustrate the significant relationship between the spatial integration of urban agglomerations and the characteristics of industrial development. In the process of spatial integration, urban form, intercity relation and their evolution show clear regional differences. Because of the differences in socio-economic and geographical characteristics, urban systems are more advanced and closely related in developed areas. A significant negative (positive) spatial correlation between industrial specialization (diversification) and urban form is supported by using bivariate Moran's I, and spatial clustering patterns are clearly different across the three urban agglomerations. A panel regression reveals that intercity relations are significantly associated with the characteristics of industrial development. Higher levels of industrial diversification and competition are associated with weaker intercity relations, while industrial structures similarities are reversed. These findings could be used to formulate reasonable policies and plans and to support future regional spatial integration and coordinated development.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0264-2751 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 2986
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Author Alzahrani, H.S.; Khuu, S.K.; Roy, M.
Title Modelling the effect of commercially available blue-blocking lenses on visual and non-visual functions Type Journal Article
Year 2019 Publication (up) Clinical & Experimental Optometry Abbreviated Journal Clin Exp Optom
Volume in press Issue Pages cxo.12959
Keywords Human Health; blue-blocking lenses; non-visual functions; transmittance; visual functions
Abstract BACKGROUND: Blue-blocking lenses (BBLs) are marketed as providing retinal protection from acute and cumulative exposure to blue light over time. The selective reduction in visible wavelengths transmitted through BBLs is known to influence the photosensitivity of retinal photoreceptors, which affects both visual and non-visual functions. This study measured the spectral transmittance of BBLs and evaluated their effect on blue perception, scotopic vision, circadian rhythm, and protection from photochemical retinal damage. METHODS: Seven different types of BBLs from six manufacturers and untinted control lenses with three different powers (+2.00 D, -2.00 D and Plano) were evaluated. The whiteness index of BBLs used in this study was calculated using Commission International de l'Eclairage (CIE) Standard Illuminates D65, and CIE 1964 Standard with a 2 degrees Observer. The protective qualities of BBLs and their effect on blue perception, scotopic vision, and circadian rhythm were evaluated based on their spectral transmittance, which was measured with a Cary 5,000 UV-Vis-NIR spectrophotometer. RESULTS: BBLs were found to reduce blue light (400-500 nm) by 6-43 per cent, providing significant protection from photochemical retinal damage compared to control lenses (p </= 0.05). All BBLs were capable of reducing the perception of blue colours, scotopic sensitivities and circadian sensitivities by 5-36 per cent, 5-24 per cent, and 4-27 per cent, respectively depending on the brand and power of the lens. CONCLUSION: BBLs can provide some protection to the human eye from photochemical retinal damage by reducing a portion of blue light that may affect visual and non-visual performances, such as those critical to scotopic vision, blue perception, and circadian rhythm.
Address School of Optometry and Vision Science, The University of New South Wales, Sydney, Australia
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0816-4622 ISBN Medium
Area Expedition Conference
Notes PMID:31441122 Approved no
Call Number GFZ @ kyba @ Serial 2654
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