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Author Zubidat, A.E.; Fares, B.; Fares, F.; Haim, A. url  doi
openurl 
  Title Artificial Light at Night of Different Spectral Compositions Differentially Affects Tumor Growth in Mice: Interaction With Melatonin and Epigenetic Pathways Type Journal Article
  Year 2018 Publication Cancer Control : Journal of the Moffitt Cancer Center Abbreviated Journal Cancer Control  
  Volume 25 Issue 1 Pages 1073274818812908  
  Keywords Human Health; 6-Smt; Cfl; EE-halogen; GDM-levels; body mass; carbon; corticosterone; cosinor analysis; light at night; yellow-LED  
  Abstract Lighting technology is rapidly advancing toward shorter wavelength illuminations that offer energy-efficient properties. Along with this advantage, the increased use of such illuminations also poses some health challenges, particularly breast cancer progression. Here, we evaluated the effects of artificial light at night (ALAN) of 4 different spectral compositions (500-595 nm) at 350 Lux on melatonin suppression by measuring its urine metabolite 6-sulfatoxymelatonin, global DNA methylation, tumor growth, metastases formation, and urinary corticosterone levels in 4T1 breast cancer cell-inoculated female BALB/c mice. The results revealed an inverse dose-dependent relationship between wavelength and melatonin suppression. Short wavelength increased tumor growth, promoted lung metastases formation, and advanced DNA hypomethylation, while long wavelength lessened these effects. Melatonin treatment counteracted these effects and resulted in reduced cancer burden. The wavelength suppression threshold for melatonin-induced tumor growth was 500 nm. These results suggest that short wavelength increases cancer burden by inducing aberrant DNA methylation mediated by the suppression of melatonin. Additionally, melatonin suppression and global DNA methylation are suggested as promising biomarkers for early diagnosis and therapy of breast cancer. Finally, ALAN may manifest other physiological responses such as stress responses that may challenge the survival fitness of the animal under natural environments.  
  Address 1 The Israeli Center for Interdisciplinary Research in Chronobiology, University of Haifa, Haifa, Israel  
  Corporate Author Thesis  
  Publisher SAGE Place of Publication Editor  
  Language English Summary Language (down) English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1073-2748 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30477310; PMCID:PMC6259078 Approved no  
  Call Number IDA @ john @ Serial 2143  
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Author Stern, M.; Broja, M.; Sansone, R.; Grone, M.; Skene, S.S.; Liebmann, J.; Suschek, C.V.; Born, M.; Kelm, M.; Heiss, C. url  doi
openurl 
  Title Blue light exposure decreases systolic blood pressure, arterial stiffness, and improves endothelial function in humans Type Journal Article
  Year 2018 Publication European Journal of Preventive Cardiology Abbreviated Journal Eur J Prev Cardiol  
  Volume 25 Issue 17 Pages 1875-1883  
  Keywords Human Health; Blue light; blood pressure; endothelial function; forearm blood flow; pulse wave velocity  
  Abstract AIMS: Previous studies have shown that ultraviolet light can lead to the release of nitric oxide from the skin and decrease blood pressure. In contrast to visible light the local application of ultraviolet light bears a cancerogenic risk. Here, we investigated whether whole body exposure to visible blue light can also decrease blood pressure and increase endothelial function in healthy subjects. METHODS: In a randomised crossover study, 14 healthy male subjects were exposed on 2 days to monochromatic blue light or blue light with a filter foil (control light) over 30 minutes. We measured blood pressure (primary endpoint), heart rate, forearm vascular resistance, forearm blood flow, endothelial function (flow-mediated dilation), pulse wave velocity and plasma nitric oxide species, nitrite and nitroso compounds (secondary endpoints) during and up to 2 hours after exposure. RESULTS: Blue light exposure significantly decreased systolic blood pressure and increased heart rate as compared to control. In parallel, blue light significantly increased forearm blood flow, flow-mediated dilation, circulating nitric oxide species and nitroso compounds while it decreased forearm vascular resistance and pulse wave velocity. CONCLUSION: Whole body irradiation with visible blue light at real world doses improves blood pressure, endothelial function and arterial stiffness by nitric oxide released from photolabile intracutanous nitric oxide metabolites into circulating blood.  
  Address Department of Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Stag Hill, Guildford GU2 7XH, UK. Email: c.heiss(at)  
  Corporate Author Thesis  
  Publisher SAGE Place of Publication Editor  
  Language English Summary Language (down) English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2047-4873 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30196723 Approved no  
  Call Number IDA @ john @ Serial 2157  
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Author Bará, S. url  doi
openurl 
  Title Characterizing the zenithal night sky brightness in large territories: how many samples per square kilometre are needed? Type Journal Article
  Year 2017 Publication Monthly Notices of the Royal Astronomical Society Abbreviated Journal  
  Volume 473 Issue 3 Pages 4164-4173  
  Keywords Instrumentation; atmospheric effects; light pollution; numerical methods; photometry  
  Abstract A recurring question arises when trying to characterize, by means of measurements or theoretical calculations, the zenithal night sky brightness throughout a large territory: how many samples per square kilometre are needed? The optimum sampling distance should allow reconstructing, with sufficient accuracy, the continuous zenithal brightness map across the whole region, whilst at the same time avoiding unnecessary and redundant oversampling. This paper attempts to provide some tentative answers to this issue, using two complementary tools: the luminance structure function and the Nyquist–Shannon spatial sampling theorem. The analysis of several regions of the world, based on the data from the New world atlas of artificial night sky brightness, suggests that, as a rule of thumb, about one measurement per square kilometre could be sufficient for determining the zenithal night sky brightness of artificial origin at any point in a region to within ±0.1 magV arcsec–2 (in the root-mean-square sense) of its true value in the Johnson–Cousins V band. The exact reconstruction of the zenithal night sky brightness maps from samples taken at the Nyquist rate seems to be considerably more demanding.  
  Address 1Departamento de Física Aplicada, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, Galicia, Spain; salva.bara(at)usc.es  
  Corporate Author Thesis  
  Publisher Oxford Academic Place of Publication Editor  
  Language English Summary Language (down) English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0035-8711 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number IDA @ john @ Serial 2164  
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Author Manríquez, P.H.; Jara, M.E.; Diaz, M.I.; Quijón, P.A.; Widdicombe, S.; Pulgar, J.; Manríquez, K.; Quintanilla-Ahumada, D.; Duarte, C. url  doi
openurl 
  Title Artificial light pollution influences behavioral and physiological traits in a keystone predator species, Concholepas concholepas Type Journal Article
  Year 2019 Publication Science of The Total Environment Abbreviated Journal Science of The Total Environment  
  Volume 661 Issue Pages 543-552  
  Keywords Animals; Concholepas concholepas; sea snails; mollusks; Muricidae  
  Abstract Artificial Light At Night (ALAN) is an increasing global problem that, despite being widely recognized in terrestrial systems, has been studied much less in marine habitats. In this study we investigated the effect of ALAN on behavioral and physiological traits of Concholepas concholepas, an important keystone species of the south-eastern Pacific coast. We used juveniles collected in intertidal habitats that had not previously been exposed to ALAN. In the laboratory we exposed them to two treatments: darkness and white LED (Lighting Emitting Diodes) to test for the impacts of ALAN on prey-searching behavior, self-righting time and metabolism. In the field, the distribution of juveniles was observed during daylight-hours to determine whether C. concholepas preferred shaded or illuminated microhabitats. Moreover, we compared the abundance of juveniles collected during day- and night-time hours. The laboratory experiments demonstrated that juveniles of C. concholepas seek out and choose their prey more efficiently in darkened areas. White LED illuminated conditions increased righting times and metabolism. Field surveys indicated that, during daylight hours, juveniles were more abundant in shaded micro-habitats than in illuminated ones. However, during darkness hours, individuals were not seen to aggregate in any particular microhabitats. We conclude that the exposure to ALAN might disrupt important behavioral and physiological traits of small juveniles in this species which, as a mechanism to avoid visual predators, are mainly active at night. It follows that ALAN in coastal areas might modify the entire community structure of intertidal habitats by altering the behavior of this keystone species.  
  Address Centro de Estudios Avanzados en Zonas Áridas (CEAZA), Coquimbo, Chile; atriciohmanriquez(at)gmail.com  
  Corporate Author Thesis  
  Publisher Elsevier Place of Publication Editor  
  Language English Summary Language (down) English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0048-9697 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2173  
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Author Franklin, M.; Chau, K.; Cushing, L.J.; Johnston, J. url  doi
openurl 
  Title Characterizing flaring from unconventional oil and gas operations in south Texas using satellite observations Type Journal Article
  Year 2019 Publication Environmental Science & Technology Abbreviated Journal Environ Sci Technol  
  Volume 53 Issue 4 Pages 2220-2228  
  Keywords Remote Sensing; petroleum; Texas; United States; VIIRS-DNB; Eagle Ford Shale; flaring; oil and gas  
  Abstract Over the past decade, increases in high-volume hydraulic fracturing for oil and gas extraction in the United States have raised concerns with residents living near wells. Flaring, or the combustion of petroleum products into the open atmosphere, is a common practice associated with oil and gas exploration and production, and has been under-examined as a potential source of exposure. We leveraged data from the Visible Infrared Imaging Spectroradiometer (VIIRS) Nightfire satellite product to characterize the extent of flaring in the Eagle Ford Shale region of south Texas, one of the most productive in the nation. Spatiotemporal hierarchical clustering identified flaring sources, and a regression-based approach combining VIIRS information with reported estimates of vented and flared gas from the Railroad Commission of Texas enabled estimation of flared gas volume at each flare. We identified 43,887 distinct oil and gas flares in the study region from 2012-2016, with a peak in activity in 2014 and an estimated 4.5 billion cubic meters of total gas volume flared over the study period. A comparison with well permit data indicated the majority of flares were associated with oil-producing (82%) and horizontally-drilled (92%) wells. Of the 49 counties in the region, 5 accounted for 71% of the total flaring. Our results suggest flaring may be a significant environmental exposure in parts of this region.  
  Address Department of Preventive Medicine, University of Southern California, Los Angeles California 90032, United States; meredith.franklin(at)usc.edu  
  Corporate Author Thesis  
  Publisher ACS Place of Publication Editor  
  Language English Summary Language (down) English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0013-936X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30657671 Approved no  
  Call Number GFZ @ kyba @ Serial 2175  
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