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Author Kennard, D.C.; Chamberlin, V.D.
Title (up) All-night Light for Layers Type Report
Year 1931 Publication Abbreviated Journal
Volume Bulletin 476 Issue Pages
Keywords Animals
Abstract
Address
Corporate Author Ohio Agricultural Experiment Station Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 2392
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Author Zhou, Y.; Zhang, H.-K.; Liu, F.; Lei, G.; Liu, P.; Jiao, T.; Dang, Y.-H.
Title (up) Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice Type Journal Article
Year 2018 Publication Frontiers in Behavioral Neuroscience Abbreviated Journal Front Behav Neurosci
Volume 12 Issue Pages 110
Keywords Animals
Abstract In recent years, the environmental impact of artificial light at night has been a rapidly growing global problem, affecting 99% of the population in the US and Europe, and 62% of the world population. The present study utilized a mouse model exposed to long-term artificial light and light deprivation to explore the impact of these conditions on emotion and cognition. Based on the potential links between histidine triad nucleotide binding protein 1 (HINT1) and mood disorders, we also examined the expression of HINT1 and related apoptosis factors in the suprachiasmatic nucleus (SCN), prefrontal cortex (PFC), nucleus accumbens (NAc) and hippocampus (Hip). Mice exposed to constant light (CL) exhibited depressive- and anxiety-like behaviors, as well as impaired spatial memory, as demonstrated by an increased immobility time in the tail suspension and forced swimming tests, less entries and time spent in the open arms of elevated plus-maze, and less platform site crossings and time spent in the target quadrant in the Morris water maze (MWM). The effects of constant darkness (CD) partially coincided with long-term illumination, except that mice in the CD group failed to show anxiety-like behaviors. Furthermore, HINT1 was upregulated in four encephalic regions, indicating that HINT1 may be involved in mood disorders and cognitive impairments due to altered light exposure. The apoptosis-related proteins, BAX and BCL-2, showed the opposite expression pattern, reflecting an activated apoptotic pathway. These findings suggest that exposure to CL and/or darkness can induce significant changes in affective and cognitive responses, possibly through HINT1-induced activation of apoptotic pathways.
Address College of Medicine & Forensics, Xi'an Jiaotong University Health Science Center, Xi'an, China
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1662-5153 ISBN Medium
Area Expedition Conference
Notes PMID:29937721; PMCID:PMC6002487 Approved no
Call Number NC @ ehyde3 @ Serial 2094
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Author Riedel, C.S.; Georg, B.; Fahrenkrug, J.; Hannibal, J.
Title (up) Altered light induced EGR1 expression in the SCN of PACAP deficient mice Type Journal Article
Year 2020 Publication PloS one Abbreviated Journal PLoS One
Volume 15 Issue 5 Pages e0232748
Keywords Animals
Abstract The brain's biological clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus and generates circadian rhythms in physiology and behavior. The circadian clock needs daily adjustment by light to stay synchronized (entrained) with the astronomical 24 h light/dark cycle. Light entrainment occurs via melanopsin expressing retinal ganglion cells (mRGCs) and two neurotransmitters of the retinohypothalamic tract (RHT), PACAP and glutamate, which transmit light information to the SCN neurons. In SCN neurons, light signaling involves the immediate-early genes Fos, Egr1 and the clock genes Per1 and Per2. In this study, we used PACAP deficient mice to evaluate PACAP's role in light induced gene expression of EGR1 in SCN neurons during early (ZT17) and late (ZT23) subjective night at high (300 lux) and low (10 lux) white light exposure. We found significantly lower levels of both EGR1 mRNA and protein in the SCN in PACAP deficient mice compared to wild type mice at early subjective night (ZT17) exposed to low but not high light intensity. No difference was found between the two genotypes at late night (ZT23) at neither light intensities. In conclusion, light mediated EGR1 induction in SCN neurons at early night at low light intensities is dependent of PACAP signaling. A role of PACAP in shaping synaptic plasticity during light stimulation at night is discussed.
Address Department of Clinical Biochemistry, Faculty of Health Sciences, Bispebjerg Hospital, University of Copenhagen, Copenhagen NV, Denmark
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1932-6203 ISBN Medium
Area Expedition Conference
Notes PMID:32379800; PMCID:PMC7205239 Approved no
Call Number GFZ @ kyba @ Serial 2915
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Author Mohamad, Y.; Haim, A.; Elsalam, Z.A.
Title (up) Altered metabolic and hormonal responses in male rats exposed to acute bright light-at-night associated with global DNA hypo-methylation Type Journal Article
Year 2019 Publication Journal of Photochemistry and Photobiology B: Biology Abbreviated Journal Journal of Photochemistry and Photobiology B: Biology
Volume 194 Issue Pages 107-118
Keywords Animals; mouse models
Abstract The association between light pollution and disruption of daily rhythms, metabolic and hormonal disorders, as well as cancer progression is well-recognized. These adverse effects could be due to nocturnal melatonin suppression. The signaling pathway by which light pollution affects metabolism and endocrine responses is unclear. We studied the effects of artificial light at night (ALAN1) on body mass, food and water intake, daily rhythms of body temperature, serum glucose and insulin in male rats. Daily rhythms of urine production and urinary 6-sulfatoxymelatonin (6-SMT2), as well as global DNA methylation in pancreas and liver tissues were also assessed. Mass gain was higher in ALAN rats compared with controls. Food intake, water consumption, glucose, insulin, and 6-SMT levels markedly lessened in response to ALAN. Conversely, urine production and body temperature were elevated in ALAN rats compared with controls. Significant 24-h rhythms were detected for all variables that were altered in mesor, amplitude, and acrophase occurrences under ALAN conditions. DNA hypo-methylation was detected in ALAN pancreatic tissue compared with controls, but not in hepatic tissue. Overall, ALAN affects metabolic and hormonal physiology in different levels in which flexible crosstalk between melatonin and both epigenetics and metabolic levels expressed as body temperature rhythm, is suggested to mediate the environmental exposure at the molecular level and subsequently physiology is altered. The flexibility of epigenetic modifications provides a potential therapeutic target for rectifying ALAN adverse effects by epigenetic markers such as melatonin and behavioral lifestyle interventions for confining ALAN exposures as much as possible.
Address Department of Human Biology, University of Haifa, Mount Carmel, Haifa 3498838, Israel
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1011-1344 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 2282
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Author Yao, J.Q.; Zhai, H.R.; Tang, X.M.; Gao, X.M.; Yang, X.D.
Title (up) Amazon Fire Monitoring and Analysis Based on Multi-source Remote Sensing Data Type Journal Article
Year 2020 Publication IOP Conference Series: Earth and Environmental Science Abbreviated Journal IOP Conf. Ser.: Earth Environ. Sci.
Volume 474 Issue Pages 042025
Keywords Remote Sensing
Abstract In August 2019, a large-scale fire broke out in the Amazon rainforest, bringing serious harm to the ecosystem and human beings. In order to accurately monitor the dynamic change of forest fire in Amazon rainforest and analyse the impact of fire spreading and extinction on the environment, firstly, based on NPP VIIRS data covering the Amazon fire area, the sliding window threshold method is adopted to extract the fire point, and the cause of fire change is monitored and analysed according to the time series. Secondly, based on the time series of CALIPSO data, the vertical distribution changes of atmospheric pollutants in the amazon fire area are analysed, and the comprehensive analysis is carried out by combining NPP VIIRS data. The experimental results show that only NPP VIIRS data is used to predict the fire, and the combination of CALIPSO data can better monitor the forest fire and predict the fire development trend. The combination of optical image and laser radar has greater advantages in dynamic fire monitoring and fire impact analysis. The method described in this paper can provide basic data reference for real-time and accurate prediction of forest fires and provide new ideas for dynamic fire monitoring.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1755-1315 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 2927
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