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Author Zhou, Y.; Zhang, H.-K.; Liu, F.; Lei, G.; Liu, P.; Jiao, T.; Dang, Y.-H. url  doi
openurl 
  Title (up) Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice Type Journal Article
  Year 2018 Publication Frontiers in Behavioral Neuroscience Abbreviated Journal Front Behav Neurosci  
  Volume 12 Issue Pages 110  
  Keywords Animals  
  Abstract In recent years, the environmental impact of artificial light at night has been a rapidly growing global problem, affecting 99% of the population in the US and Europe, and 62% of the world population. The present study utilized a mouse model exposed to long-term artificial light and light deprivation to explore the impact of these conditions on emotion and cognition. Based on the potential links between histidine triad nucleotide binding protein 1 (HINT1) and mood disorders, we also examined the expression of HINT1 and related apoptosis factors in the suprachiasmatic nucleus (SCN), prefrontal cortex (PFC), nucleus accumbens (NAc) and hippocampus (Hip). Mice exposed to constant light (CL) exhibited depressive- and anxiety-like behaviors, as well as impaired spatial memory, as demonstrated by an increased immobility time in the tail suspension and forced swimming tests, less entries and time spent in the open arms of elevated plus-maze, and less platform site crossings and time spent in the target quadrant in the Morris water maze (MWM). The effects of constant darkness (CD) partially coincided with long-term illumination, except that mice in the CD group failed to show anxiety-like behaviors. Furthermore, HINT1 was upregulated in four encephalic regions, indicating that HINT1 may be involved in mood disorders and cognitive impairments due to altered light exposure. The apoptosis-related proteins, BAX and BCL-2, showed the opposite expression pattern, reflecting an activated apoptotic pathway. These findings suggest that exposure to CL and/or darkness can induce significant changes in affective and cognitive responses, possibly through HINT1-induced activation of apoptotic pathways.  
  Address College of Medicine & Forensics, Xi'an Jiaotong University Health Science Center, Xi'an, China  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1662-5153 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:29937721; PMCID:PMC6002487 Approved no  
  Call Number NC @ ehyde3 @ Serial 2094  
Permanent link to this record
 

 
Author Mohamad, Y.; Haim, A.; Elsalam, Z.A. url  doi
openurl 
  Title (up) Altered metabolic and hormonal responses in male rats exposed to acute bright light-at-night associated with global DNA hypo-methylation Type Journal Article
  Year 2019 Publication Journal of Photochemistry and Photobiology B: Biology Abbreviated Journal Journal of Photochemistry and Photobiology B: Biology  
  Volume in press Issue Pages  
  Keywords Animals  
  Abstract The association between light pollution and disruption of daily rhythms, metabolic and hormonal disorders, as well as cancer progression is well-recognized. These adverse effects could be due to nocturnal melatonin suppression. The signaling pathway by which light pollution affects metabolism and endocrine responses is unclear. We studied the effects of artificial light at night (ALAN1) on body mass, food and water intake, daily rhythms of body temperature, serum glucose and insulin in male rats. Daily rhythms of urine production and urinary 6-sulfatoxymelatonin (6-SMT2), as well as global DNA methylation in pancreas and liver tissues were also assessed. Mass gain was higher in ALAN rats compared with controls. Food intake, water consumption, glucose, insulin, and 6-SMT levels markedly lessened in response to ALAN. Conversely, urine production and body temperature were elevated in ALAN rats compared with controls. Significant 24-h rhythms were detected for all variables that were altered in mesor, amplitude, and acrophase occurrences under ALAN conditions. DNA hypo-methylation was detected in ALAN pancreatic tissue compared with controls, but not in hepatic tissue. Overall, ALAN affects metabolic and hormonal physiology in different levels in which flexible crosstalk between melatonin and both epigenetics and metabolic levels expressed as body temperature rhythm, is suggested to mediate the environmental exposure at the molecular level and subsequently physiology is altered. The flexibility of epigenetic modifications provides a potential therapeutic target for rectifying ALAN adverse effects by epigenetic markers such as melatonin and behavioral lifestyle interventions for confining ALAN exposures as much as possible.  
  Address  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1011-1344 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2282  
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Author Raap, T.; Pinxten, R.; Casasole, G.; Dehnhard, N.; Eens, M. url  doi
openurl 
  Title (up) Ambient anthropogenic noise but not light is associated with the ecophysiology of free-living songbird nestlings Type Journal Article
  Year 2017 Publication Scientific Reports Abbreviated Journal Sci Rep  
  Volume 7 Issue 1 Pages 2754  
  Keywords Animals  
  Abstract Urbanization is associated with dramatic increases in noise and light pollution, which affect animal behaviour, physiology and fitness. However, few studies have examined these stressors simultaneously. Moreover, effects of urbanization during early-life may be detrimental but are largely unknown. In developing great tits (Parus major), a frequently-used model species, we determined important indicators of immunity and physiological condition: plasma haptoglobin (Hp) and nitric oxide (NOx) concentration. We also determined fledging mass, an indicator for current health and survival. Associations of ambient noise and light exposure with these indicators were studied. Anthropogenic noise, light and their interaction were unrelated to fledging mass. Nestlings exposed to more noise showed higher plasma levels of Hp but not of NOx. Light was unrelated to Hp and NOx and did not interact with the effect of noise on nestlings' physiology. Increasing levels of Hp are potentially energy demanding and trade-offs could occur with life-history traits, such as survival. Effects of light pollution on nestlings of a cavity-nesting species appear to be limited. Nonetheless, our results suggest that the urban environment, through noise exposure, may entail important physiological costs for developing organisms.  
  Address Department of Biology, Behavioural Ecology and Ecophysiology Group, University of Antwerp, Wilrijk, Belgium  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2045-2322 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28584270; PMCID:PMC5459827 Approved no  
  Call Number GFZ @ kyba @ Serial 2451  
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Author Aceituno, J.; Sánchez, S.F.; Aceituno, F.J.; Galadí-Enríquez, D.; Negro, J.J.; Soriguer, R.C.; Gomez, G.S. url  doi
openurl 
  Title (up) An All-Sky Transmission Monitor: ASTMON Type Journal Article
  Year 2011 Publication Publications of the Astronomical Society of the Pacific Abbreviated Journal Publications of the Astronomical Society of the Pacific  
  Volume 123 Issue 907 Pages 1076-1086  
  Keywords monitoring; light at night; light pollution; skyglow  
  Abstract We present here the All-Sky Transmission Monitor (ASTMON), designed to perform a continuous monitoring of the surface brightness of the complete night sky in several bands. The data acquired are used to derive, in addition, a subsequent map of the multiband atmospheric extinction at any location in the sky and a map of the cloud coverage. The instrument has been manufactured to withstand extreme weather conditions and to remain operative. Designed to be fully robotic, it is ideal to be installed outdoors as a permanent monitoring station. The preliminary results based on two of the currently operative units (at Doñana National Park, Huelva, and at the Calar Alto Observatory, Almería, Spain) are presented here. The parameters derived using ASTMON are in good agreement with those previously reported, which illustrates the validity of the design and the accuracy of the manufacturing. The information provided by this instrument will be presented in forthcoming articles, once we have accumulated a statistically significant amount of data.  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0004-6280 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number IDA @ john @ Serial 195  
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Author Bowden, J. url  doi
openurl 
  Title (up) An Analysis of Factors Affecting Catches of Insects in Light-Traps Type Journal Article
  Year 1982 Publication Bulletin of Entomological Research Abbreviated Journal Bull. Entomol. Res.  
  Volume 72 Issue 4 Pages 535-556  
  Keywords Ecology; Animals  
  Abstract Analysis of published data on catches of insects in light-traps with a variety of light sources and of different designs showed that all conformed to the previously proposed model describing the functioning of a light-trap: catch = constant × where W = trap illumination and I = background illumination. Light-trap catches in differing cloud conditions and in open and woodland situations also varied as predicted by the model. A table of correction factors for different amounts of cloud cover is provided. The results are discussed in relation to use of light-traps and interpretation of light-trap data.  
  Address  
  Corporate Author Thesis  
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  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0007-4853 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2589  
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