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Author (up) Shen, J.; Tower, J.
Title Effects of light on aging and longevity Type Journal Article
Year 2019 Publication Ageing Research Reviews Abbreviated Journal Ageing Res Rev
Volume in press Issue Pages
Keywords Review; Human Health
Abstract Increasing evidence suggests an important role for light in regulation of aging and longevity. UV radiation is a mutagen that can promote aging and decrease longevity. In contrast, NIR light has shown protective effects in animal disease models. In invertebrates, visible light can shorten or extend lifespan, depending on the intensity and wavelength composition. Visible light also impacts human health, including retina function, sleep, cancer and psychiatric disorders. Possible mechanisms of visible light include: controlling circadian rhythms, inducing oxidative stress, and acting through the retina to affect neuronal circuits and systems. Changes in artificial lighting (e.g., LEDs) may have implications for human health. It will be important to further explore the mechanisms of how light affects aging and longevity, and how light affects human health.
Address Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles CA 90089-2910, United States
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1568-1637 ISBN Medium
Area Expedition Conference
Notes PMID:31154014 Approved no
Call Number GFZ @ kyba @ Serial 2514
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