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Author (up) Price, L.L.A.; Udovicic, L.; Behrens, T.; van Drongelen, A.; Garde, A.H.; Hogenelst, K.; Jensen, M.A.; Khazova, M.; Nowak, K.; Rabstein, S.; Romanus, E.; Wolska, A.
Title Linking the non-visual effects of light exposure with occupational health Type Journal Article
Year 2019 Publication International Journal of Epidemiology Abbreviated Journal Int J Epidemiol
Volume 48 Issue 5 Pages 1393–1397
Keywords Commentary; Review; Human Health; non-visual effects
Abstract In May 2018, the Federal Institute for Occupational Safety and Health (BAuA, Germany) hosted ‘Light and Health at Work’, a workshop concerning occupational health issues relating to non-visual effects of light of both indoor and shift workers. The agenda reflected a common interest in translational research linking laboratory findings with occupational and public health outcomes, and resulted in the founding of the European scientific network NoVEL (standing for Non-Visual Effects of Light). This article sets out the network participants’ shared goals to improve the scientific evidence about light’s non-visual effects, circadian disruption and well-being, using light exposure interventions with high quality assessment of light.

The main work conditions that impair exposure profiles that support healthy circadian regulation are daytime indoor work that reduces light exposures and night-shift work that increases light-at-night (LAN).
Address Central Institute for Labour Protection – National Research Institute (CIOP-PIB), Warszawa, Poland
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
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ISSN 0300-5771 ISBN Medium
Area Expedition Conference
Notes PMID:31257447 Approved no
Call Number GFZ @ kyba @ Serial 2566
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Author (up) Stevens, R.G.
Title Light-at-night, circadian disruption and breast cancer: assessment of existing evidence Type Journal Article
Year 2009 Publication International Journal of Epidemiology Abbreviated Journal Int J Epidemiol
Volume 38 Issue 4 Pages 963-970
Keywords Human Health; Animals; Blindness/complications/epidemiology; Breast Neoplasms/epidemiology/*etiology/metabolism; Chronobiology Disorders/*complications/epidemiology/metabolism; Circadian Rhythm/physiology; Disease Models, Animal; Female; Humans; Light Signal Transduction/physiology; Lighting/adverse effects; Melatonin/biosynthesis; Sleep/physiology; Time Factors; *Work Schedule Tolerance
Abstract BACKGROUND: Breast cancer incidence is increasing globally for largely unknown reasons. The possibility that a portion of the breast cancer burden might be explained by the introduction and increasing use of electricity to light the night was suggested >20 years ago. METHODS: The theory is based on nocturnal light-induced disruption of circadian rhythms, notably reduction of melatonin synthesis. It has formed the basis for a series of predictions including that non-day shift work would increase risk, blind women would be at lower risk, long sleep duration would lower risk and community nighttime light level would co-distribute with breast cancer incidence on the population level. RESULTS: Accumulation of epidemiological evidence has accelerated in recent years, reflected in an International Agency for Research on Cancer (IARC) classification of shift work as a probable human carcinogen (2A). There is also a strong rodent model in support of the light-at-night (LAN) idea. CONCLUSION: If a consensus eventually emerges that LAN does increase risk, then the mechanisms for the effect are important to elucidate for intervention and mitigation. The basic understanding of phototransduction for the circadian system, and of the molecular genetics of circadian rhythm generation are both advancing rapidly, and will provide for the development of lighting technologies at home and at work that minimize circadian disruption, while maintaining visual efficiency and aesthetics. In the interim, there are strategies now available to reduce the potential for circadian disruption, which include extending the daily dark period, appreciate nocturnal awakening in the dark, using dim red light for nighttime necessities, and unless recommended by a physician, not taking melatonin tablets.
Address Department of Community Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-6325, USA. bugs@uchc.edu
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0300-5771 ISBN Medium
Area Expedition Conference
Notes PMID:19380369; PMCID:PMC2734067 Approved no
Call Number LoNNe @ christopher.kyba @ Serial 527
Permanent link to this record