|   | 
Details
   web
Records
Author (up) Davis, S.; Mirick, D.K.; Stevens, R.G.
Title Night Shift Work, Light at Night, and Risk of Breast Cancer Type Journal Article
Year 2001 Publication JNCI Journal of the National Cancer Institute Abbreviated Journal JNCI Journal of the National Cancer Institute
Volume 93 Issue 20 Pages 1557-1562
Keywords light at night; oncogenesis; melatonin; shiftwork; breast cancer; *Cancer
Abstract Exposure to light at night may increase the risk of breast cancer by suppressing the normal nocturnal production of melatonin by the pineal gland, which, in turn, could increase the release of estrogen by the ovaries. This study investigated whether such exposure is associated with an increased risk of breast cancer in women. Methods: Case patients (n = 813), aged 20–74 years, were diagnosed from November 1992 through March 1995; control subjects (n = 793) were identified by random-digit dialing and were frequency matched according to 5-year age groups. An in-person interview was used to gather information on sleep habits and bedroom lighting environment in the 10 years before diagnosis and lifetime occupational history. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated by use of conditional logistic regression, with adjustment for other potential risk factors. Results: Breast cancer risk was increased among subjects who frequently did not sleep during the period of the night when melatonin levels are typically at their highest (OR = 1.14 for each night per week; 95% CI = 1.01 to 1.28). Risk did not increase with interrupted sleep accompanied by turning on a light. There was an indication of increased risk among subjects with the brightest bedrooms. Graveyard shiftwork was associated with increased breast cancer risk (OR = 1.6; 95% CI = 1.0 to 2.5), with a trend of increased risk with increasing years and with more hours per week of graveyard shiftwork (P = .02, Wald chi-squared test). Conclusion: The results of this study provide evidence that indicators of exposure to light at night may be associated with the risk of developing breast cancer.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0027-8874 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number IDA @ john @ Serial 164
Permanent link to this record
 

 
Author (up) Hansen, J.
Title Light at Night, Shiftwork, and Breast Cancer Risk Type Journal Article
Year 2001 Publication JNCI Journal of the National Cancer Institute Abbreviated Journal JNCI Journal of the National Cancer Institute
Volume 93 Issue 20 Pages 1513-1515
Keywords Human Health
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0027-8874 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number LoNNe @ kagoburian @ Serial 758
Permanent link to this record
 

 
Author (up) Schernhammer, E.S.; Laden, F.; Speizer, F.E.; Willett, W.C.; Hunter, D.J.; Kawachi, I.; Colditz, G.A.
Title Rotating Night Shifts and Risk of Breast Cancer in Women Participating in the Nurses' Health Study Type Journal Article
Year 2001 Publication JNCI Journal of the National Cancer Institute Abbreviated Journal JNCI Journal of the National Cancer Institute
Volume 93 Issue 20 Pages 1563-1568
Keywords Human Health
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0027-8874 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number LoNNe @ kagoburian @ Serial 806
Permanent link to this record
 

 
Author (up) Schernhammer, E.S.; Laden, F.; Speizer, F.E.; Willett, W.C.; Hunter, D.J.; Kawachi, I.; Fuchs, C.S.; Colditz, G.A.
Title Night-Shift Work and Risk of Colorectal Cancer in the Nurses' Health Study Type Journal Article
Year 2003 Publication JNCI Journal of the National Cancer Institute Abbreviated Journal JNCI Journal of the National Cancer Institute
Volume 95 Issue 11 Pages 825-828
Keywords Human Health
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0027-8874 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number LoNNe @ kagoburian @ Serial 807
Permanent link to this record