| Records |
| Author |
Dumont, M.; Beaulieu, C. |
| Title |
Light exposure in the natural environment: relevance to mood and sleep disorders |
Type |
Journal Article |
| Year |
2007 |
Publication |
Sleep Medicine |
Abbreviated Journal |
Sleep Med |
| Volume |
8 |
Issue |
6 |
Pages |
557-565 |
| Keywords |
Human Health; Affect; *Biological Clocks; *Circadian Rhythm; Humans; *Light; Mood Disorders/*etiology; Sleep Disorders, Circadian Rhythm/*complications; Wakefulness; Work Schedule Tolerance |
| Abstract |
In addition to being necessary for vision, light also plays a primary role in circadian physiology. Humans are diurnal animals and their biological clock synchronizes their physiological functions in such a way that functions associated with activity happen in the daytime while functions associated with rest occur at night. A misalignment between the endogenous circadian clock and the desired sleep schedule is the main cause of circadian sleep disorders; it may be involved in certain mood disorders as well. Since light is the main environmental cue used by the biological clock to set its own timing in relation to the day-night cycle, inappropriate light exposure can be involved in the physiopathology of circadian disorders. Conversely, when handled properly, controlled light exposure can be used to treat some mood and sleep disorders. While the earliest studies in the field focused solely on exposure to bright light, contemporary studies aim at understanding how the entire profile of light-dark exposure can influence the circadian clock and, consequently, mood, sleep, and vigilance quality. Following a brief summary of the main concepts underlying the non-visual effects of light, this paper presents some studies using ambulatory measurements of light exposure to illustrate how these concepts apply in real-life situations and discusses the clinical relevance of light exposure in the natural environment for mood, sleep, and circadian disorders. |
| Address |
Chronobiology Laboratory, Sacre-Coeur Hospital of Montreal, Montreal, Quebec, Canada H4J 1C5. marie.dumont@umontreal.ca |
| Corporate Author |
|
Thesis |
|
| Publisher |
|
Place of Publication |
|
Editor |
|
| Language |
English |
Summary Language |
|
Original Title |
|
| Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
| Series Volume |
|
Series Issue |
|
Edition |
|
| ISSN |
1389-9457 |
ISBN |
|
Medium |
|
| Area |
|
Expedition |
|
Conference |
|
| Notes |
PMID:17383230 |
Approved |
no |
Call Number  |
LoNNe @ kagoburian @ |
Serial |
736 |
| Permanent link to this record |
| |
|
| |
| Author |
Escobar, C.; Salgado-Delgado, R.; Gonzalez-Guerra, E.; Tapia Osorio, A.; Angeles-Castellanos, M.; Buijs, R.M. |
| Title |
Circadian disruption leads to loss of homeostasis and disease |
Type |
Journal Article |
| Year |
2011 |
Publication |
Sleep Disorders |
Abbreviated Journal |
Sleep Disord |
| Volume |
2011 |
Issue |
|
Pages |
964510 |
| Keywords |
Human Health |
| Abstract |
The relevance of a synchronized temporal order for adaptation and homeostasis is discussed in this review. We present evidence suggesting that an altered temporal order between the biological clock and external temporal signals leads to disease. Evidence mainly based on a rodent model of “night work” using forced activity during the sleep phase suggests that altered activity and feeding schedules, out of phase from the light/dark cycle, may be the main cause for the loss of circadian synchrony and disease. It is proposed that by avoiding food intake during sleep hours the circadian misalignment and adverse consequences can be prevented. This review does not attempt to present a thorough revision of the literature, but instead it aims to highlight the association between circadian disruption and disease with special emphasis on the contribution of feeding schedules in circadian synchrony. |
| Address |
Departamento de Anatomia, Facultad de Medicina, Universidad Nacional Autonoma de Mexico, 04360 Mexico City, DF, Mexico |
| Corporate Author |
|
Thesis |
|
| Publisher |
|
Place of Publication |
|
Editor |
|
| Language |
English |
Summary Language |
|
Original Title |
|
| Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
| Series Volume |
|
Series Issue |
|
Edition |
|
| ISSN |
2090-3553 |
ISBN |
|
Medium |
|
| Area |
|
Expedition |
|
Conference |
|
| Notes |
PMID:23471148; PMCID:PMC3581131 |
Approved |
no |
| Call Number |
LoNNe @ kagoburian @ |
Serial |
745 |
| Permanent link to this record |
| |
|
| |
| Author |
Lack, L.C.; Gradisar, M.; Van Someren, E.J.W.; Wright, H.R.; Lushington, K. |
| Title |
The relationship between insomnia and body temperatures |
Type |
Journal Article |
| Year |
2008 |
Publication |
Sleep Medicine Reviews |
Abbreviated Journal |
Sleep Med Rev |
| Volume |
12 |
Issue |
4 |
Pages |
307-317 |
| Keywords |
Human Health; Arousal/physiology; Body Temperature Regulation/*physiology; Circadian Rhythm/physiology; Homeostasis/physiology; Humans; Melatonin/blood; Phototherapy; Skin Temperature/physiology; Sleep Disorders, Circadian Rhythm/physiopathology/therapy; Sleep Initiation and Maintenance Disorders/*physiopathology/therapy; Sympathetic Nervous System/physiopathology; Wakefulness/physiology |
| Abstract |
Sleepiness and sleep propensity are strongly influenced by our circadian clock as indicated by many circadian rhythms, most commonly by that of core body temperature. Sleep is most conducive in the temperature minimum phase, but is inhibited in a “wake maintenance zone” before the minimum phase, and is disrupted in a zone following that phase. Different types of insomnia symptoms have been associated with abnormalities of the body temperature rhythm. Sleep onset insomnia is associated with a delayed temperature rhythm presumably, at least partly, because sleep is attempted during a delayed evening wake maintenance zone. Morning bright light has been used to phase advance circadian rhythms and successfully treat sleep onset insomnia. Conversely, early morning awakening insomnia has been associated with a phase advanced temperature rhythm and has been successfully treated with the phase delaying effects of evening bright light. Sleep maintenance insomnia has been associated not with a circadian rhythm timing abnormality, but with nocturnally elevated core body temperature. Combination of sleep onset and maintenance insomnia has been associated with a 24-h elevation of core body temperature supporting the chronic hyper-arousal model of insomnia. The possibility that these last two types of insomnia may be related to impaired thermoregulation, particularly a reduced ability to dissipate body heat from distal skin areas, has not been consistently supported in laboratory studies. Further studies of thermoregulation are needed in the typical home environment in which the insomnia is most evident. |
| Address |
School of Psychology, Flinders University, South Australia, Australia. leon.lack@flinders.edu.au |
| Corporate Author |
|
Thesis |
|
| Publisher |
|
Place of Publication |
|
Editor |
|
| Language |
English |
Summary Language |
|
Original Title |
|
| Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
| Series Volume |
|
Series Issue |
|
Edition |
|
| ISSN |
1087-0792 |
ISBN |
|
Medium |
|
| Area |
|
Expedition |
|
Conference |
|
| Notes |
PMID:18603220 |
Approved |
no |
| Call Number |
LoNNe @ kagoburian @ |
Serial |
775 |
| Permanent link to this record |
| |
|
| |
| Author |
Skene, D.J.; Arendt, J. |
| Title |
Circadian rhythm sleep disorders in the blind and their treatment with melatonin |
Type |
Journal Article |
| Year |
2007 |
Publication |
Sleep Medicine |
Abbreviated Journal |
Sleep Med |
| Volume |
8 |
Issue |
6 |
Pages |
651-655 |
| Keywords |
Human Health; Blindness/*complications; Chronotherapy; Circadian Rhythm/drug effects; Humans; Melatonin/*administration & dosage; Sleep/drug effects; Sleep Disorders, Circadian Rhythm/*drug therapy/*etiology; Treatment Outcome |
| Abstract |
People who are blind, in addition to having to cope with partial or no sight, have an added handicap; the transmission of ocular light from the retina to their circadian clock is impaired. At its worse, for example in people with both eyes enucleated, this lesion results in desynchronisation of the biological clock (located in the hypothalamic suprachiasmatic nuclei) from the 24h day/night environment. While in a desynchronised state, symptoms akin to jet lag are experienced (e.g., daytime sleepiness, poor night sleep, reduced alertness and performance during waking). This is a lifelong condition. Daily administration of exogenous melatonin is the current treatment of choice for this so-called “non-24h sleep/wake disorder”. Melatonin has been shown to correct the underlying circadian rhythm abnormality as well as improve sleep and reduce daytime napping. The effectiveness of melatonin therapy depends upon its time of administration relative to the timing of the person's circadian clock. If practicable, assessment of an individual's circadian phase (by measurement of the endogenous melatonin rhythm in plasma, saliva or urine) is recommended prior to commencing treatment to optimise melatonin's effectiveness. |
| Address |
Centre for Chronobiology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK. d.skene@surrey.ac.uk |
| Corporate Author |
|
Thesis |
|
| Publisher |
|
Place of Publication |
|
Editor |
|
| Language |
English |
Summary Language |
|
Original Title |
|
| Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
| Series Volume |
|
Series Issue |
|
Edition |
|
| ISSN |
1389-9457 |
ISBN |
|
Medium |
|
| Area |
|
Expedition |
|
Conference |
|
| Notes |
PMID:17420154 |
Approved |
no |
| Call Number |
LoNNe @ kagoburian @ |
Serial |
811 |
| Permanent link to this record |
| |
|
| |
| Author |
Crowley, S.J.; Suh, C.; Molina, T.A.; Fogg, L.F.; Sharkey, K.M.; Carskadon, M.A. |
| Title |
Estimating the dim light melatonin onset of adolescents within a 6-h sampling window: the impact of sampling rate and threshold method |
Type |
Journal Article |
| Year |
2015 |
Publication |
Sleep Medicine |
Abbreviated Journal |
Sleep Medicine |
| Volume |
20 |
Issue |
|
Pages |
59-66 |
| Keywords |
Human Health |
| Abstract |
|
| Address |
|
| Corporate Author |
|
Thesis |
|
| Publisher |
|
Place of Publication |
|
Editor |
|
| Language |
|
Summary Language |
|
Original Title |
|
| Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
| Series Volume |
|
Series Issue |
|
Edition |
|
| ISSN |
1389-9457 |
ISBN |
|
Medium |
|
| Area |
|
Expedition |
|
Conference |
|
| Notes |
|
Approved |
no |
| Call Number |
LoNNe @ kyba @ |
Serial |
1324 |
| Permanent link to this record |
