| Records |
| Author |
WDS Killgore |
| Title |
Lighting the Way to Better Sleep and Health |
Type |
Journal Article |
| Year |
2016 |
Publication |
Journal of Sleep Disorders: Treatment and Care |
Abbreviated Journal |
J Sleep Disor: Treat Care |
| Volume |
05 |
Issue |
01 |
Pages |
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| Keywords |
Health; Editorial |
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Edition |
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| ISSN |
2325-9639 |
ISBN |
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| Notes |
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Approved |
no |
Call Number  |
LoNNe @ kyba @ |
Serial |
1442 |
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| Author |
Peixoto, C.A.T.; da Silva, A.G.T.; Carskadon, M.A.; Louzada, F.M. |
| Title |
Adolescents living in homes without electric lighting have earlier sleep times |
Type |
Journal Article |
| Year |
2009 |
Publication |
Behavioral Sleep Medicine |
Abbreviated Journal |
Behav Sleep Med |
| Volume |
7 |
Issue |
2 |
Pages |
73-80 |
| Keywords |
Human Health; Sleep |
| Abstract |
The aim of this project was to compare circadian rhythmicity of a group of 37 adolescents (14 girls), aged 11 to 16 (mean age = 13.1 +/- 1.7 years), with and without electricity at home. Twenty students attended morning school (07:30-11:30), and 17 attended evening school classes (19:00-22:30). Eleven adolescents had no electric lighting at home (5 attended morning classes and 6 attended evening classes). They completed a sleep log and wore a wrist actigraph for 5 consecutive days. Saliva samples were collected to assess DLMO. Data were compared by ANOVA and showed later timing and a more extended sleep period for those who attended late classes. Those adolescents without electricity at home had significantly earlier sleep onset on school days. As to DLMO, a trend to a delay was observed in the groups who had electric lighting. |
| Address |
Department of Physiology, Universidade Federal do Parana, Brazil. pedatardelli@yahoo.com.br |
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| Language |
English |
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| ISSN |
1540-2002 |
ISBN |
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| Notes |
PMID:19330580 |
Approved |
no |
| Call Number |
LoNNe @ kyba @ |
Serial |
1481 |
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| Author |
Pereira, É.F.; Louzada, F.M.; Moreno, C.R.C. |
| Title |
Not all adolescents are sleep deprived: A study of rural populations: Sleep duration in rural populations |
Type |
Journal Article |
| Year |
2010 |
Publication |
Sleep and Biological Rhythms |
Abbreviated Journal |
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| Volume |
8 |
Issue |
4 |
Pages |
267-273 |
| Keywords |
Human Health; Sleep |
| Abstract |
The objective of this study was to investigate the role of environmental factors in sleep duration among adolescents living in rural areas. A total of 1140 students (569 males), aged 10–19 years, and attending two schools in rural regions in southern Brazil, completed a questionnaire about their sleep habits. Demographic data were also obtained. Prevalence ratios (PR) were estimated for the cases of more than 9 h of sleep on weekdays. Sleep duration in adolescents with and without electric lighting at home was analyzed. Average sleep duration at night was 9.63 (1.64) h on school-going days and 10.14 (2.42) h on weekends. The prevalence of adolescents sleeping for more than 9 h at night on school-going days was 58.3%. Older adolescents showed a tendency to delay their sleep onset times, which is associated with a reduction of sleep duration. Adolescents without electric lighting at home slept longer on school-going days (P < 0.001) and on weekends (P= 0.013) when compared to those with electric lighting at home. From multivariate analysis, age (P < 0.001), school schedule (P= 0.007) and work (0.042) were factors affecting sleep duration. In contrast to the data previously reported for urban populations, we found a high prevalence of adolescents sleeping for more than 9 h on school nights. Data on populations living in less industrialized regions reinforce the idea that technological advances are associated with the negative impact of sleep phase delay in adolescents. |
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| ISSN |
1446-9235 |
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no |
| Call Number |
LoNNe @ kyba @ |
Serial |
1482 |
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| Author |
Wang, H.-B.; Whittaker, D.S.; Truong, D.; Mulji, A.K.; Ghiani, C.A.; Loh, D.H.; Colwell, C.S. |
| Title |
Blue light therapy improves circadian dysfunction as well as motor symptoms in two mouse models of Huntington's disease |
Type |
Journal Article |
| Year |
2017 |
Publication |
Neurobiology of Sleep and Circadian Rhythms |
Abbreviated Journal |
Neurobiology of Sleep and Circadian Rhythms |
| Volume |
2 |
Issue |
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Pages |
39-52 |
| Keywords |
animals; Human Health |
| Abstract |
Patients with Huntington's disease (HD) exhibit movement disorders, psychiatric disturbance and cognitive impairments as the disease progresses. Abnormal sleep/wake cycles are common among HD patients with reports of delayed sleep onset, fatigue during the day, and a delayed pattern of melatonin secretion all of which suggest circadian dysfunction. Mouse models of HD confirm disrupted circadian rhythms with pathophysiology found in the central circadian clock (suprachiasmatic nucleus). Importantly, circadian dysfunction manifests early in disease, even before the classic motor symptoms, in both patients and mouse models. Therefore, we hypothesize that the circadian dysfunction may interact with the disease pathology and exacerbate the HD symptoms. If correct, early intervention may benefit patients and delay disease progression. One test of this hypothesis is to determine whether light therapy designed to strengthen this intrinsic timing system can delay the disease progression in mouse models. Therefore, we determined the impact of blue wavelength-enriched light on two HD models: the BACHD and Q175 mice. Both models received 6 hours of blue-light at the beginning of their daily light cycle for 3 months. After treatment, both genotypes showed improvements in their locomotor activity rhythm without significant change to their sleep behavior. Critically, treated mice of both lines exhibited improved motor performance compared to untreated controls. Focusing on the Q175 genotype, we sought to determine whether the treatment altered signaling pathways in brain regions known to be impacted by HD using NanoString gene expression assays. We found that the expression of several HD relevant markers was altered in the striatum and cortex of the treated mice. Our study demonstrates that strengthening the circadian system can delay the progression of HD in pre-clinical models. This work suggests that lighting conditions should be considered when managing treatment of HD and other neurodegenerative disorders. |
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| ISSN |
2451-9944 |
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no |
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LoNNe @ kyba @ |
Serial |
1626 |
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| Author |
Joo, E.Y.; Abbott, S.M.; Reid, K.J.; Wu, D.; Kang, J.; Wilson, J.; Zee, P.C. |
| Title |
Timing of light exposure and activity in adults with delayed sleep-wake phase disorder |
Type |
Journal Article |
| Year |
2016 |
Publication |
Sleep Medicine |
Abbreviated Journal |
Sleep Med |
| Volume |
32 |
Issue |
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Pages |
259-265 |
| Keywords |
Human Health |
| Abstract |
OBJECTIVE: To characterize the patterns of light exposure and physical activity level and assess their relationship with sleep quality and depressive symptoms in adults with delayed sleep-wake phase disorder (DSWPD). METHODS: 42 DSWPD (22 female, mean age 34.5 y) and 26 (+/-4 years) age-and-sex-matched controls (12 female, mean age 33.4 y) underwent seven days of light and activity monitoring. RESULTS: Individuals with DSWPD had significantly delayed bed times and wake times, but similar sleep duration compared to controls. Subjective sleep quality (Pittsburgh Sleep Quality Index (PSQI)) was poorer in DSWPDs compared to controls. Those with DSWPD had significantly more activity and light exposure late at night (2:00-4:00) and significantly less activity and light exposure in the morning (8:00-11:00). Total 24 h levels of light and activity were not significantly different between DSWPD and controls. However, the DSWPD group had significantly more light exposure than controls 22 h after waking, during their sleep period. Later light exposure correlated with higher depression scores [Beck Depression Index (BDI)] and poorer sleep quality (PSQI). CONCLUSIONS: The light exposure patterns observed in DSWPD likely contribute to and perpetuate the chronically delayed sleep and wake phase in these patients. In addition, increased light exposure during the sleep period may also contribute to the poor sleep quality and mood disorders that are common in these individuals. |
| Address |
Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA. Electronic address: p-zee@northwestern.edu |
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English |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1389-9457 |
ISBN |
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| Notes |
PMID:27964860 |
Approved |
no |
| Call Number |
LoNNe @ kyba @ |
Serial |
1639 |
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