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Author Ohayon, M.M.; Milesi, C.
Title Artificial Outdoor Nighttime Lights Associate with Altered Sleep Behavior in the American General Population Type Journal Article
Year 2016 Publication Sleep Abbreviated Journal Sleep
Volume 39 Issue 6 Pages 1311-1320
Keywords Human Health; Remote Sensing; Sleep
Abstract STUDY OBJECTIVES: Our study aims to explore the associations between outdoor nighttime lights (ONL) and sleep patterns in the human population. METHODS: Cross-sectional telephone study of a representative sample of the general US population age 18 y or older. 19,136 noninstitutionalized individuals (participation rate: 83.2%) were interviewed by telephone. The Sleep-EVAL expert system administered questions on life and sleeping habits; health; sleep, mental and organic disorders (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision; International Classification of Sleep Disorders, Second Edition; International Classification of Diseases, 10(th) Edition). Individuals were geolocated by longitude and latitude. Outdoor nighttime light measurements were obtained from the Defense Meteorological Satellite Program's Operational Linescan System (DMSP/OLS), with nighttime passes taking place between 19:30 and 22:30 local time. Light data were correlated precisely to the geolocation of each participant of the general population sample. RESULTS: Living in areas with greater ONL was associated with delayed bedtime (P < 0.0001) and wake up time (P < 0.0001), shorter sleep duration (P < 0.01), and increased daytime sleepiness (P < 0.0001). Living in areas with greater ONL also increased the dissatisfaction with sleep quantity and quality (P < 0.0001) and the likelihood of having a diagnostic profile congruent with a circadian rhythm disorder (P < 0.0001). CONCLUSIONS: Although they improve the overall safety of people and traffic, nighttime lights in our streets and cities are clearly linked with modifications in human sleep behaviors and also impinge on the daytime functioning of individuals living in areas with greater ONL.
Address NASA Ames Research Center, Moffett Field, CA
Corporate Author Thesis
Publisher Place of Publication Editor
Language (up) English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0161-8105 ISBN Medium
Area Expedition Conference
Notes PMID:27091523; PMCID:PMC4863221 Approved no
Call Number GFZ @ kyba @ Serial 2551
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Author Obayashi, K.; Yamagami, Y.; Kurumatani, N.; Saeki, K.
Title Bedroom lighting environment and incident diabetes mellitus: a longitudinal study of the HEIJO-KYO cohort Type Journal Article
Year 2019 Publication Sleep Medicine Abbreviated Journal Sleep Medicine
Volume 65 Issue Pages 1-3
Keywords Human Health; Metabolic disorders; diabetes; geriatrics
Abstract Objectives

Light information received by the brain influences human circadian timing and metabolism; low-level light at night (LAN) significantly increased body mass and led to prediabetes in mice. We hypothesized that LAN exposure increases the diabetes risk in humans. The aim of the present study was to evaluate a longitudinal association between LAN exposure and the incidence of diabetes in a general population.

Methods

In our prospective cohort study, bedroom light intensity was measured at 1-min intervals in 678 elderly participants without diabetes at baseline. The average light intensity recorded between bedtimes and rise times over two consecutive nights was used in the analysis.

Results

During follow-up (median, 42 months), 19 of the 678 participants (mean age, 70.6 years) developed diabetes. Poisson regression models revealed that the incidence rate for diabetes was significantly higher in the LAN group (average ≥5 lux, N = 128) than the dark group (average <5 lux, N = 550) (incidence rate ratio, 3.74; 95% confidence interval (CI), 1.55–9.05; p=0.003). Further propensity score adjustments in relation to LAN produced consistent results (incidence rate ratio, 3.19; 95% CI, 1.38–7.35; p=0.007). When the cut-off value of LAN was decreased to 3 lux, the relationship remained significant (incidence rate ratio 2.74; 95% CI, 1.19–6.33; p=0.018).

Conclusions

Our findings suggest that LAN exposure increases the incidence of diabetes in a general elderly population. Further research involving a large cohort with new-onset diabetes is warranted to elucidate these findings.
Address Department of Epidemiology, Nara Medical University School of Medicine, 840 Shijocho, Kashiharashi, Nara, 634-8521, Japan; obayashi(at)naramed-u.ac.jp
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language (up) English Summary Language English Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1389-9457 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 2605
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Author Savarese, M.; Di Perri, M.C.
Title Excessive sleepiness in shift work disorder: a narrative review of the last 5 years Type Journal Article
Year 2019 Publication Sleep & Breathing = Schlaf & Atmung Abbreviated Journal Sleep Breath
Volume Issue Pages 1-14
Keywords Human Health; Alertness; Armodafinil; Insomnia; Performance; Shift work disorder; excessive sleepiness; StimulaCentral Nervous System Stimulants; Review
Abstract INTRODUCTION: Shift work sleep disorder (SWSD), also known as shift work disorder (SWD), is a circadian rhythm sleep disorder characterized by insomnia and/or excessive sleepiness, associated with a recurring work schedule that overlaps the usual time designated for sleeping. PURPOSE: This article aims to provide a narrative review of the pharmacological trials conducted on SWD in the last 5 years, to better address safety and health issues inherent to this disorder. METHODS: An electronic literature search was conducted using PubMed. All eligible randomized controlled trials (RCTs) and cross-over RCTs with employees undertaking shift work (including night shifts) were considered, yielding three articles. RESULTS: All three studies showed the efficacy of armodafinil in improving subjective and objective sleepiness, clinical conditions, and global functioning regardless of shift duration. Both performance and driving simulator performance tests administered during the night shift bore better results following armodafinil administration than after placebo. However, armodafinil only reduced subjective disability in individuals working more than 9 h; furthermore, even after armodafinil, alertness was reduced but not normalized. CONCLUSION: These studies underscore the importance of preventing and/or minimizing disturbances due to shift work. This may be achieved through various strategies, such as the employer's commitment to adopt ergonomic criteria in shift design and to implement work-environment interventions like controlled bright light. Health personnel is of pivotal importance to detect potential factors of intolerance to shift work or early symptoms of SWD. Additional and improved studies are needed to further evaluate the effectiveness and safety of both pharmacological and non-pharmacological interventions.
Address Center of Sleep Medicine, UOSD of Neurophysiopathology and Disorders of Movement, AOU G Martino, Department of Clinical and Experimental Medicine, University of Messina, 98121, Messina, Italy. mdiperri@wesleyan.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language (up) English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1520-9512 ISBN Medium
Area Expedition Conference
Notes PMID:31471831 Approved no
Call Number GFZ @ kyba @ Serial 2662
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Author Sletten, T.L.; Cappuccio, F.P.; Davidson, A.J.; Van Cauter, E.; Rajaratnam, S.M.W.; Scheer, F.A.J.L.
Title Health consequences of circadian disruption Type Journal Article
Year 2020 Publication Sleep Abbreviated Journal Sleep
Volume 43 Issue 1 Pages
Keywords Human Health; Circadian Rhythm; Chronobiology; Sleep; Review
Abstract The circadian system is key for optimal functioning by maintaining synchrony between internal circadian rhythms, behaviors, and external cues. Many clinicians are not fully aware, however, of the far-reaching implications of the circadian system for human health. Clinical attention to circadian rhythms has largely focused on sleep disturbances. The impact of the circadian system on health is, however, much broader. Clinical diagnoses are often based on single time point assessments during the day, ignoring circadian influences on physiology. Even when time is considered, using (external) clock time ignores the large interindividual differences in internal timing.
Address Division of Sleep Medicine, Harvard Medical School, Boston, MA
Corporate Author Thesis
Publisher Place of Publication Editor
Language (up) English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0161-8105 ISBN Medium
Area Expedition Conference
Notes PMID:31930347 Approved no
Call Number IDA @ john @ Serial 2822
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Author Juda, M.; Liu-Ambrose, T.; Feldman, F.; Suvagau, C.; Mistlberger, R.E.
Title Light in the Senior Home: Effects of Dynamic and Individual Light Exposure on Sleep, Cognition, and Well-Being Type Journal Article
Year 2020 Publication Clocks & Sleep Abbreviated Journal Clocks Sleep
Volume 2 Issue 4 Pages 557-576
Keywords Human health; aging; circadian rhythms; cognition; entrainment; light; nursing home; sleep
Abstract Disrupted sleep is common among nursing home patients and is associated with cognitive decline and reduced well-being. Sleep disruptions may in part be a result of insufficient daytime light exposure. This pilot study examined the effects of dynamic “circadian” lighting and individual light exposure on sleep, cognitive performance, and well-being in a sample of 14 senior home residents. The study was conducted as a within-subject study design over five weeks of circadian lighting and five weeks of conventional lighting, in a counterbalanced order. Participants wore wrist accelerometers to track rest-activity and light profiles and completed cognitive batteries (National Institute of Health (NIH) toolbox) and questionnaires (depression, fatigue, sleep quality, lighting appraisal) in each condition. We found no significant differences in outcome variables between the two lighting conditions. Individual differences in overall (indoors and outdoors) light exposure levels varied greatly between participants but did not differ between lighting conditions, except at night (22:00-6:00), with maximum light exposure being greater in the conventional lighting condition. Pooled data from both conditions showed that participants with higher overall morning light exposure (6:00-12:00) had less fragmented and more stable rest-activity rhythms with higher relative amplitude. Rest-activity rhythm fragmentation and long sleep duration both uniquely predicted lower cognitive performance.
Address Sleep and Circadian Neuroscience Laboratory, Department of Psychology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada
Corporate Author Thesis
Publisher Place of Publication Editor
Language (up) English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2624-5175 ISBN Medium
Area Expedition Conference
Notes PMID:33327499; PMCID:PMC7768397 Approved no
Call Number GFZ @ kyba @ Serial 3261
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