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Author Obayashi, K.; Yamagami, Y.; Kurumatani, N.; Saeki, K.
Title Bedroom lighting environment and incident diabetes mellitus: a longitudinal study of the HEIJO-KYO cohort Type Journal Article
Year 2019 Publication Sleep Medicine Abbreviated Journal Sleep Medicine
Volume 65 Issue Pages 1-3
Keywords Human Health; Metabolic disorders; diabetes; geriatrics
Abstract Objectives

Light information received by the brain influences human circadian timing and metabolism; low-level light at night (LAN) significantly increased body mass and led to prediabetes in mice. We hypothesized that LAN exposure increases the diabetes risk in humans. The aim of the present study was to evaluate a longitudinal association between LAN exposure and the incidence of diabetes in a general population.

Methods

In our prospective cohort study, bedroom light intensity was measured at 1-min intervals in 678 elderly participants without diabetes at baseline. The average light intensity recorded between bedtimes and rise times over two consecutive nights was used in the analysis.

Results

During follow-up (median, 42 months), 19 of the 678 participants (mean age, 70.6 years) developed diabetes. Poisson regression models revealed that the incidence rate for diabetes was significantly higher in the LAN group (average ≥5 lux, N = 128) than the dark group (average <5 lux, N = 550) (incidence rate ratio, 3.74; 95% confidence interval (CI), 1.55–9.05; p=0.003). Further propensity score adjustments in relation to LAN produced consistent results (incidence rate ratio, 3.19; 95% CI, 1.38–7.35; p=0.007). When the cut-off value of LAN was decreased to 3 lux, the relationship remained significant (incidence rate ratio 2.74; 95% CI, 1.19–6.33; p=0.018).

Conclusions

Our findings suggest that LAN exposure increases the incidence of diabetes in a general elderly population. Further research involving a large cohort with new-onset diabetes is warranted to elucidate these findings.
Address Department of Epidemiology, Nara Medical University School of Medicine, 840 Shijocho, Kashiharashi, Nara, 634-8521, Japan; obayashi(at)naramed-u.ac.jp
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language English Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1389-9457 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial (down) 2605
Permanent link to this record
 

 
Author Ohayon, M.M.; Milesi, C.
Title Artificial Outdoor Nighttime Lights Associate with Altered Sleep Behavior in the American General Population Type Journal Article
Year 2016 Publication Sleep Abbreviated Journal Sleep
Volume 39 Issue 6 Pages 1311-1320
Keywords Human Health; Remote Sensing; Sleep
Abstract STUDY OBJECTIVES: Our study aims to explore the associations between outdoor nighttime lights (ONL) and sleep patterns in the human population. METHODS: Cross-sectional telephone study of a representative sample of the general US population age 18 y or older. 19,136 noninstitutionalized individuals (participation rate: 83.2%) were interviewed by telephone. The Sleep-EVAL expert system administered questions on life and sleeping habits; health; sleep, mental and organic disorders (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision; International Classification of Sleep Disorders, Second Edition; International Classification of Diseases, 10(th) Edition). Individuals were geolocated by longitude and latitude. Outdoor nighttime light measurements were obtained from the Defense Meteorological Satellite Program's Operational Linescan System (DMSP/OLS), with nighttime passes taking place between 19:30 and 22:30 local time. Light data were correlated precisely to the geolocation of each participant of the general population sample. RESULTS: Living in areas with greater ONL was associated with delayed bedtime (P < 0.0001) and wake up time (P < 0.0001), shorter sleep duration (P < 0.01), and increased daytime sleepiness (P < 0.0001). Living in areas with greater ONL also increased the dissatisfaction with sleep quantity and quality (P < 0.0001) and the likelihood of having a diagnostic profile congruent with a circadian rhythm disorder (P < 0.0001). CONCLUSIONS: Although they improve the overall safety of people and traffic, nighttime lights in our streets and cities are clearly linked with modifications in human sleep behaviors and also impinge on the daytime functioning of individuals living in areas with greater ONL.
Address NASA Ames Research Center, Moffett Field, CA
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0161-8105 ISBN Medium
Area Expedition Conference
Notes PMID:27091523; PMCID:PMC4863221 Approved no
Call Number GFZ @ kyba @ Serial (down) 2551
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Author Dhaliwal, S.S.; Keller, J.; Le, H.-N.; Lewin, D.S.
Title Sleep Disturbance among Pregnant Women: The Influence of Environmental and Contextual Factors Type Journal Article
Year 2019 Publication Sleep Abbreviated Journal
Volume 42 Issue Supplement_1 Pages A270-A271
Keywords Human Health
Abstract Introduction

Disrupted sleep during pregnancy affects nearly 85% of women. This can contribute to psychological distress and antenatal depression. The aims of the current project were to test whether (a) poorer subjective sleep quality contributed to greater depression and anxiety symptoms, and (b) contextual factors predicted clinically significant sleep disturbance after adjusting for socioeconomic status (SES).

Methods

In a mixed-methods study, 418 pregnant women (age: M=32.4 years; gestation: M=28.4 weeks, SD=8.4 weeks; 58% Black) completed the Pittsburgh Sleep Quality Index (PSQI), measures of pregnancy-related physiological factors, and provided details about their sleep environment. They also rated perinatal depression, anxiety, and SES (Hollingshead and MacArthur Ladder). Sixty-two women completed these measures again later in pregnancy (gestation M = 34.2 weeks). A subset of seven women underwent actigraphy (9-nights) during their third trimester. Logistic regressions adjusted for age, BMI, race, sleep disordered breathing, and gestational week.

Results

Subjective sleep quality was significantly poorer among Black women and those with higher BMI. Physiological factors (i.e., restless leg syndrome, nocturnal urination, and acid reflux) explained subjective sleep disturbance after accounting for gestational week (ps<.01). Among women with history of psychopathology (n=221), sleep disturbance was significantly related to anxiety and depression symptoms (ps<.01), with greater sleep disturbance (PSQI score >5) predicting clinically significant antenatal depression (B = .38, p<.05). However, those who rated their social standing as higher reported lower sleep disturbance throughout pregnancy, even after adjusting for mood and anxiety (B= .86, SE =.41; p<.05). There was a dose-response positive association between sleep disturbance and depression severity among Black women only (B = .89; p<.05). Among lower SES Black women, environmental factors (greater ambient noise and light pollution) partially mediated this effect (B= .45, SE =.17; p<.01).

Conclusion

Sociocontextual factors may explain sleep disturbance severity among low-income pregnant Black women, above and beyond traditional metrics of SES. Higher subjective SES may be protective against sleep disturbance and psychiatric distress. Assessments of sleep during pregnancy should account for physiological considerations and environmental disruptions, alongside mood and anxiety.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0161-8105 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial (down) 2323
Permanent link to this record
 

 
Author Mindel, J.W.; Rojas, S.L.; Kline, D.; Bao, S.; Rezai, A.; Corrigan, J.D.; Nelson, R.J.; D, P.; Magalang, U.J.
Title 0038 Sleeping with Low Levels of Artificial Light at Night Increases Systemic Inflammation in Humans Type Journal Article
Year 2019 Publication Sleep Abbreviated Journal
Volume 42 Issue Supplement_1 Pages A15-A16
Keywords Human Health
Abstract Introduction

Artificial light at night (ALAN) has become a ubiquitous part of our society. Animal studies have shown that ALAN exposure promotes a depressive-like mood and increases peripheral inflammation likely due to circadian disruption. We hypothesized that sleeping with ALAN will increase systemic inflammation in humans.

Methods

We enrolled 64 subjects [32 with obstructive sleep apnea (OSA) adherent to treatment and 32 without sleep disorders] in a randomized, crossover study to determine the effects of sleeping with ALAN (40 lux) or the usual dark condition (control) for 7 nights at home. Sleeping with ALAN was confirmed by an actigraph with an ambient light sensor. Outcome measurements were done at baseline and after sleeping in each condition. The primary outcome was changes in the high-sensitivity C-reactive protein (hsCRP) levels. Secondary outcomes include scores on the Pittsburgh Sleep Quality Index (PSQI), Center for Epidemiologic Studies Depression Scale (CES-D), Functional Outcomes of Sleep Questionnaire-10 (FOSQ-10), and Epworth Sleepiness Scale (ESS); Psychomotor Vigilance Testing (PVT); actigraphic sleep measures; and homeostatic model assessment of insulin resistance (HOMA-IR). A random effects linear regression model was used to assess differences adjusting for schedule, visit, and baseline levels. Post-hoc analyses combined results from OSA and non-OSA subjects.

Results

Fifty-eight (30 OSA and 28 non-OSA) subjects, aged 38.4±14.9 years, 33 of whom are male completed the protocol. A log transformation was used so the difference in hsCRP was expressed as a mean ratio. In the combined analysis, the mean hsCRP was 39% higher with ALAN than control (mean ratio=1.39; 95% CI: 1.08-1.80; p=0.012). The effects of ALAN for OSA and non-OSA subjects were not different. ALAN increased the CES-D score by 1.81 (p=0.017) and ESS score by 0.62 (p=0.071) points, and decreased the FOSQ-10 score by 0.36 (p=0.038) points while the PSQI score was unchanged (p=0.860). There were no significant differences in the PVT values, actigraphic sleep measures, or HOMA-IR.

Conclusion

Sleeping with ALAN for seven days significantly increased hsCRP levels and modestly increased depression scores in humans.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0161-8105 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial (down) 2322
Permanent link to this record
 

 
Author Prayag, A.; Münch, M.; Aeschbach, D.; Chellappa, S.; Gronfier, C.
Title Light Modulation of Human Clocks, Wake, and Sleep Type Journal Article
Year 2019 Publication Clocks & Sleep Abbreviated Journal Clocks & Sleep
Volume 1 Issue 1 Pages 193-208
Keywords Human Health; Review
Abstract Light, through its non-imaging forming effects, plays a dominant role on a myriad of physiological functions, including the human sleep–wake cycle. The non-image forming effects of light heavily rely on specific properties such as intensity, duration, timing, pattern, and wavelengths. Here, we address how specific properties of light influence sleep and wakefulness in humans through acute effects, e.g., on alertness, and/or effects on the circadian timing system. Of critical relevance, we discuss how different characteristics of light exposure across the 24-h day can lead to changes in sleep–wake timing, sleep propensity, sleep architecture, and sleep and wake electroencephalogram (EEG) power spectra. Ultimately, knowledge on how light affects sleep and wakefulness can improve light settings at home and at the workplace to improve health and well-being and optimize treatments of chronobiological disorders.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2624-5175 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial (down) 2266
Permanent link to this record