toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
Details
   print
  Record Links
Author (up) Bonmati-Carrion, M.; Arguelles-Prieto, R.; Martinez-Madrid, M.; Reiter, R.; Hardeland, R.; Rol, M.; Madrid, J. url  doi
openurl 
  Title Protecting the Melatonin Rhythm through Circadian Healthy Light Exposure Type Journal Article
  Year 2014 Publication International Journal of Molecular Sciences Abbreviated Journal IJMS  
  Volume 15 Issue 12 Pages 23448-23500  
  Keywords human health; chronodisruption; circadian; light at night (LAN); melanopsin; melatonin  
  Abstract Currently, in developed countries, nights are excessively illuminated (light at night), whereas daytime is mainly spent indoors, and thus people are exposed to much lower light intensities than under natural conditions. In spite of the positive impact of artificial light, we pay a price for the easy access to light during the night: disorganization of our circadian system or chronodisruption (CD), including perturbations in melatonin rhythm. Epidemiological studies show that CD is associated with an increased incidence of diabetes, obesity, heart disease, cognitive and affective impairment, premature aging and some types of cancer. Knowledge of retinal photoreceptors and the discovery of melanopsin in some ganglion cells demonstrate that light intensity, timing and spectrum must be considered to keep the biological clock properly entrained. Importantly, not all wavelengths of light are equally chronodisrupting. Blue light, which is particularly beneficial during the daytime, seems to be more disruptive at night, and induces the strongest melatonin inhibition. Nocturnal blue light exposure is currently increasing, due to the proliferation of energy-efficient lighting (LEDs) and electronic devices. Thus, the development of lighting systems that preserve the melatonin rhythm could reduce the health risks induced by chronodisruption. This review addresses the state of the art regarding the crosstalk between light and the circadian system.  
  Address Department of Physiology, Faculty of Biology, University of Murcia, Murcia 30100, Spain  
  Corporate Author Thesis  
  Publisher MDPI Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1422-0067 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number IDA @ john @ Serial 1078  
Permanent link to this record
Select All    Deselect All
 |   | 
Details
   print

Save Citations:
Export Records: