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Author (up) Masri, S.; Sassone-Corsi, P. url  doi
  Title The emerging link between cancer, metabolism, and circadian rhythms Type Journal Article
  Year 2018 Publication Nature Medicine Abbreviated Journal Nat Med  
  Volume 24 Issue 12 Pages 1795-1803  
  Keywords Human Health; Review  
  Abstract The circadian clock is a complex cellular mechanism that, through the control of diverse metabolic and gene expression pathways, governs a large array of cyclic physiological processes. Epidemiological and clinical data reveal a connection between the disruption of circadian rhythms and cancer that is supported by recent preclinical data. In addition, results from animal models and molecular studies underscore emerging links between cancer metabolism and the circadian clock. This has implications for therapeutic approaches, and we discuss the possible design of chronopharmacological strategies.  
  Address Department of Biological Chemistry, Center for Epigenetics and Metabolism, INSERM U1233, University of California Irvine, Irvine, CA, USA.  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1078-8956 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30523327 Approved no  
  Call Number GFZ @ kyba @ Serial 2135  
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