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Author (up) Lee, H.-S.; Lee, E.; Moon, J.-H.; Kim, Y.J.; Lee, H.-J. url  doi
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  Title Circadian disruption and increase of oxidative stress in male and female volunteers after bright light exposure before bed time Type Journal Article
  Year 2019 Publication Molecular & Cellular Toxicology Abbreviated Journal Mol. Cell. Toxicol.  
  Volume 15 Issue 2 Pages 221-229  
  Keywords Human Health  
  Abstract Backgrounds

Circadian rhythms are patterns of behaviour, physiology, and metabolism that occur within a period of approximately 24 h. The higher risk of breast and prostate cancers among shift workers, as well as the general population, are reported to be associated with circadian rhythm disruption caused by exposure to light at night. We focused on the effects of bright light before bed comparing effects between men and women.

Methods

Male and female healthy volunteers aged 20–30 were exposed to 4 hours of bright light before bed for 3 and 4 days.

Results

We analyzed the shift of circadian rhythms of subjects based on cortisol secretion patterns in response to short periods of bright-light exposure at bedtime. We also found an increase of oxidative stress including MDA, 8-OHdG, and total antioxidants in both male and female volunteers.

Conclusion

These results suggest that bright light exposure before sleep, often encounter in modern daily life, has a considerable influence on the human body. The chronic effects of light exposure before bed time such as the carcinogenic effects caused by circadian disruption and oxidative stress need further investigation.
 
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  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1738-642X ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2331  
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