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Author (up) Torres-Farfan, C.; Mendez, N.; Ehrefeld, P.; Seron-Ferre, M. url  doi
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  Title In utero circadian changes; facing light pollution Type Journal Article
  Year 2019 Publication Current Opinion in Physiology Abbreviated Journal Current Opinion in Physiology  
  Volume 13 Issue Pages 128-134  
  Keywords Human Health; Review; In Utero; Pregnancy; Circadian Rhythm  
  Abstract Regardless of the molecular and physiological mechanisms involved, maternal fetal circadian systems interactions are recognized as crucial crosstalk for fetal development, and in turn, it may be a key factor determining fitting health in adulthood. However, in the last 100 years, life on the planet has altered the natural light-dark cycle by increasing light at night inducing disorganization of the circadian system, i.e. chronodisruption, including perturbation of the melatonin circadian rhythm by decreasing its nocturnal peak. The reduction in melatonin is associated with gradual losses in antioxidant protection, immunological and anti-inflammatory effects and as stated by WHO, the lack of nocturnal peak of melatonin is a deleterious signal that may induce chronic disease and cancer. Collectively the current review provides evidence about the role played by maternal circadian rhythms in fetal development and the impact of fetal-maternal desynchronization in the health and diseases of the offspring.  
  Address Laboratory of Developmental Chronobiology, Faculty of Medicine, Universidad Austral de Chile, Valdivia, Chile; claudia.torres(at)uach.cl  
  Corporate Author Thesis  
  Publisher Elsever Place of Publication Editor  
  Language English Summary Language English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2468-8673 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2761  
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