||(1) background: Urban representations of the Amazon are urgently needed in order tobetter understand the complexity of urban processes in this area of the World. So far, limited workthat represents Amazonian urban regions has been carried out. (2) methods: Our study area is theEcuadorian Amazon. We performed a K-means algorithm using six urban indicators: Urban fractaldimension, number of paved streets, urban radiant intensity (luminosity), and distances to theclosest new deforested areas, to oil pollution sources, and to mining pollution sources. We alsocarried out fieldwork to qualitatively validate our geospatial and statistical analyses. (3) results:We generated six Amazonian urban regions representing different urban configurations and processesof major cities, small cities, and emerging urban zones. The Amazonian urban regions generatedrepresent the urban systems of the Ecuadorian Amazon at a general scale, and correspond to theurban realities at a local scale. (4) conclusions: An Amazonian urban region is understood as a set ofurban zones that are dispersed and share common urban characteristics such a similar distance tooil pollution sources or similar urban radiant intensity. Our regionalization model represents thecomplexity of the Amazonian urban systems, and the applied methodology could be transferred toother Amazonian countries.