toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
  Record Links
Author (up) Feng T.; Li Z.; Li S. url  openurl
  Title Effects of Constant Light on the Behavioral Parameters in Rats Type Journal Article
  Year 2019 Publication International Journal of Psychiatric and Mental Health Abbreviated Journal  
  Volume Issue Pages in press  
  Keywords Animals  
  Abstract Light pollution is one of the most rapidly increasing types of environmental degradation, especially in the hospital ward and ICUs. Exposure to constant light (LL) condition disrupts circadian rhythms in behavioral, physiological and endocrinal processes. Whether melatonin can reverse those disruptions remains unclear. We used male Sprague – Dawley rats (7 weeks of age at the time of purchase)to explore 1) the effects of LL condition on social memory, anxiety–like behavior and circadian system, 2) whether exogenous melatonin can reverse the changes. Compared with LD + Veh (LD: standard 12h:12hlight-dark cycles; Veh: receive vehicle intraperitoneal injection) group, rats exposed to LL for two weeks had less anxiety-like behavior, impaired the social memory, elongated the rhythm cycle of free running wheel and disrupted secretion of corticosterone (Cort) and melatonin (Mel). Application of exogenous melatonin couldn't rescue the impairment of the social memory and the disrupted circadian system. These findings suggest that LL condition can disorganize the circadian system and exogenous melatonin cannot reverse these changes.  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number UP @ altintas1 @ Serial 3209  
Permanent link to this record
Select All    Deselect All
 |   | 

Save Citations:
Export Records: