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Author (up) Hannibal, J. url  doi
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  Title Action of Light on the Neuroendocrine Axis Type Book Chapter
  Year 2021 Publication Neuroendocrine Clocks and Calendars Abbreviated Journal  
  Volume Issue Pages  
  Keywords Human Health; Photoentrainment; circadian rhythm; Neuroendocrine Axis; neuroendocrine system; hypothalamic-pituitary-adrenal axis; hypothalamic-pituitary-thyroid axis; hypothalamic-pituitary-gonadal axis; artificial light at night  
  Abstract Photoentrainment of the circadian clock located in the hypothalamic suprachiasmatic nucleus (SCN) is fundamental for the stable regulation of neuroendocrine function underlying physiological functions such as metabolism, sleep, immune responses, and reproduction. Masking by light directly suppresses melatonin secretion independent of the circadian system, with impact on several neuroendocrine axes. This chapter describes recent findings in anatomy and physiology on how light mediates its effects on SCN-regulated timing of the neuroendocrine system, including the hypothalamic-pituitary-adrenal (HPA) axis, the hypothalamic-pituitary-thyroid (HPT) axis, the hypothalamic-pituitary-gonadal (HPG) axis, and melatonin and arginine-vasopressin (AVP) secretion. In modern societies, artificial light at night (ALAN) seems to affect circadian and neuroendocrine systems, and should be considered in the understanding the health problems of the industrialized human population.  
  Address Department of Clinical Biochemistry Bispebjerg Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; j.hannibal ( at ) dadlnet.dk  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language English Original Title  
  Series Editor Ebling F.J.P., Piggins H.D. Series Title Masterclass in Neuroendocrinology Abbreviated Series Title  
  Series Volume 10 Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number IDA @ john @ Serial 3411  
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