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Author (up) Bray, M.S.; Young, M.E. url  doi
  Title Chronobiological Effects on Obesity Type Journal Article
  Year 2012 Publication Current Obesity Reports Abbreviated Journal Curr Obes Rep  
  Volume 1 Issue 1 Pages 9-15  
  Keywords Human Health; Chronobiological effects; Circadian; Gene; Molecular clock; Obesity; Rhythm; Shift work; Sleep; Transcription  
  Abstract The development of obesity is the consequence of a multitude of complex interactions between both genetic and environmental factors. It has been suggested that the dramatic increase in the prevalence of obesity over the past 30 years has been the result of environmental changes that have enabled the full realization of genetic susceptibility present in the population. Among the many environmental alterations that have occurred in our recent history is the ever-increasing dyssynchrony between natural cycles of light/dark and altered patterns of sleep/wake and eating behavior associated with our “24-hour” lifestyle. An extensive research literature has established clear links between increased risk for obesity and both sleep deprivation and shift work, and our understanding of the consequences of such dyssynchrony at the molecular level is beginning to emerge. Studies linking alterations in cellular circadian clocks to metabolic dysfunction point to the increasing importance of chronobiology in obesity etiology.  
  Address Departments of Epidemiology and Genetics, University of Alabama at Birmingham, Birmingham, AL  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2162-4968 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23682347; PMCID:PMC3653336 Approved no  
  Call Number LoNNe @ christopher.kyba @ Serial 510  
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