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Author (up) Lahti, T.; Merikanto, I.; Partonen, T. url  doi
openurl 
  Title Circadian clock disruptions and the risk of cancer Type Journal Article
  Year 2012 Publication Annals of Medicine Abbreviated Journal Ann Med  
  Volume 44 Issue 8 Pages 847-853  
  Keywords Human Health; Cell Division; Chronobiology Disorders/*complications/genetics/*physiopathology; Circadian Clocks/*genetics; Humans; Neoplasms/*etiology; Work Schedule Tolerance/physiology  
  Abstract Disrupted circadian rhythms may lead to failures in the control of the cell division cycle and the subsequent malignant cell growth. In order to understand the pathogenesis of cancer more in detail, it is crucial to identify those mechanisms of action which contribute to the loss of control of the cell division cycle. This mini-review focuses on the recent findings concerning the links between the human circadian clock and cancer. Clinical implications concern not only feasible methods for the assessment of the circadian time of an individual or for the determination of the best time for administration of a drug of treatment, but also in the future genetic tests for screening and for planning treatment.  
  Address Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0785-3890 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23072403 Approved no  
  Call Number LoNNe @ christopher.kyba @ Serial 513  
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