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Author (up) Wright, K.P.J.; Hull, J.T.; Czeisler, C.A. url  doi
openurl 
  Title Relationship between alertness, performance, and body temperature in humans Type Journal Article
  Year 2002 Publication American Journal of Physiology. Regulatory, Integrative and Comparative Physiology Abbreviated Journal Am J Physiol Regul Integr Comp Physiol  
  Volume 283 Issue 6 Pages R1370-7  
  Keywords Human Health; Adult; Attention/*physiology; *Body Temperature; Circadian Rhythm/physiology; Cognition/*physiology; Female; Humans; Male; Memory/physiology; Reaction Time; Sleep/physiology; Time Factors; Wakefulness/physiology; NASA Discipline Regulatory Physiology; Non-NASA Center  
  Abstract Body temperature has been reported to influence human performance. Performance is reported to be better when body temperature is high/near its circadian peak and worse when body temperature is low/near its circadian minimum. We assessed whether this relationship between performance and body temperature reflects the regulation of both the internal biological timekeeping system and/or the influence of body temperature on performance independent of circadian phase. Fourteen subjects participated in a forced desynchrony protocol allowing assessment of the relationship between body temperature and performance while controlling for circadian phase and hours awake. Most neurobehavioral measures varied as a function of internal biological time and duration of wakefulness. A number of performance measures were better when body temperature was elevated, including working memory, subjective alertness, visual attention, and the slowest 10% of reaction times. These findings demonstrate that an increased body temperature, associated with and independent of internal biological time, is correlated with improved performance and alertness. These results support the hypothesis that body temperature modulates neurobehavioral function in humans.  
  Address Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. kenneth.wright@colorado.edu  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0363-6119 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:12388468 Approved no  
  Call Number LoNNe @ kagoburian @ Serial 835  
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