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Author  |
Anisimov, V. N. |
| Title |
LIGHT DESYNCHRONOSIS AND HEALTH. |
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Journal Article |
| Year |
2019 |
Publication |
Light & Engineering |
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27 |
Issue |
3 |
Pages |
14-25 |
| Keywords |
Review; Human Health |
| Abstract |
The review summarizes the modern knowledge of the impact of day-night, light-darkness rhythm disorders on the aging process and on the risk of development of the age-related conditions. Significant evidence has been obtained of that the constant artificial illumination and the daylight of the North has a stimulating effect on the occurrence and development of tumours in laboratory animals. It has been shown that long-term shift work, trans-meridian flights (jet-lag) and insomnia increase the risk of cardiovascular diseases, diabetes mellitus, and malignancies in humans. Particular attention is given to the studies where the relationship between light intensity, light wavelength and its ability to suppress the synthesis of melatonin produced at night in the pineal gland, are investigated. It has been established that melatonin synthesis is most effectively suppressed with blue light sources of a wavelength from 446 to 477 nm. The use of exogenous melatonin prevents premature aging of the reproductive system and the body as a whole prevents the development of immune-suppression, metabolic syndrome and tumours caused by light pollution. An urgent task is to develop recommendations for optimizing the illumination of workplaces and residential premises, of cities and towns as a prevention measure for premature aging and age-related pathology, which, ultimately, will contribute to the long-term maintaining of performance and improving the quality of life. |
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IDA @ intern @ |
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2642 |
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Anisimov, V.N.; Vinogradova, I.A.; Panchenko, A.V.; Popovich, I.G.; Zabezhinskii, M.A. |
| Title |
Light-at-Night-Induced Circadian Disruption, Cancer and Aging |
Type |
Journal Article |
| Year |
2012 |
Publication |
Current Aging Science |
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5 |
Issue |
3 |
Pages |
170-177 |
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Animals; Light-at-night; aging; cancer; cardiovascular diseases; circadian; circadian rhythm; diabetes; disruption; melatonin; shift-work |
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Light-at-night has become an increasing and essential part of the modern lifestyle and leads to a number of health problems, including excessive body mass index, cardiovascular diseases, diabetes, and cancer. The International Agency for Research on Cancer (IARC) Working Group concluded that “shift-work that involves circadian disruption is probably carcinogenic to humans†(Group 2A) [1]. According to the circadian disruption hypothesis, light-at-night might disrupt the endogenous circadian rhythm and specifically suppress nocturnal production of the pineal hormone melatonin and its secretion into the blood. We evaluated the effect of various light/dark regimens on the survival, life span, and spontaneous and chemical carcinogenesis in rodents. Exposure to constant illumination was followed by accelerated aging and enhanced spontaneous tumorigenesis in female CBA and transgenic HER-2/neu mice. In male and female rats maintained at various light/dark regimens (standard 12:12 light/dark [LD], the natural light [NL] of northwestern Russia, constant light [LL], and constant darkness [DD]) from the age of 25 days until natural death, it was found that exposure to NL and LL regimens accelerated age-related switch-off of the estrous function (in females), induced development of metabolic syndrome and spontaneous tumorigenesis, and shortened life span both in male and females rats compared to the standard LD regimen. Melatonin given in nocturnal drinking water prevented the adverse effect of the constant illumination (LL) and natural light (NL) regimens on the homeostasis, life span, and tumor development both in mice and rats. The exposure to the LL regimen accelerated colon carcinogenesis induced by 1,2-dimethylhydrazine (DMH) in rats, whereas the treatment with melatonin alleviated the effects of LL. The maintenance of rats at the DD regimen inhibited DMH-induced carcinogenesis. The LL regimen accelerated, whereas the DD regimen inhibited both mammary carcinogenesis induced by N-nitrosomethylurea and transplacental carcinogenesis induced by N-nitrosoethylurea in rats. Treatment with melatonin prevented premature aging and tumorigenesis in rodents. The data found in the literature and our observations suggest that the use of melatonin would be effective for cancer prevention in humans at risk as a result of light pollution. |
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LoNNe @ christopher.kyba @ |
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377 |
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Apostol, K.; Dumroese, R.K.; Pinto, J.R.; Davis, A.S. |
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Response of conifer species from three latitudinal populations to light spectra generated by light-emitting diodes and high-pressure sodium lamps |
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Journal Article |
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2015 |
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Canadian Journal of Forest Research |
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Can. J. For. Res. |
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45 |
Issue |
12 |
Pages |
1711-1719 |
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plants |
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Light-emitting diode (LED) technology shows promise for supplementing photosynthetically active radiation (PAR) in forest nurseries because of the potential reduction in energy consumption and an ability to supply discrete wavelengths to optimize seedling growth. Our objective was to examine the effects of light spectra supplied by LED and traditional high-pressure sodium (HPS) lamps on growth and physiology of Pseudotsuga menziesii (Douglas-fir) and Picea engelmannii (Engelmann spruce) seedlings. We used three latitudinal sources for each species: British Columbia (BC), Idaho (ID), and New Mexico (NM). Container seedlings were grown for 17 weeks in the greenhouse under an 18-h photoperiod of ambient solar light supplemented with light delivered from HPS or LED. In general, seedlings grown under LED had significantly greater growth, gas exchange rates, and chlorophyll contents than those seedlings grown under HPS. The growth and physiological responses to supplemental lighting varied greatly among species and seed sources. Generally, LED-grown seedlings from BC had the greatest growth and tissue dry matter followed by ID and NM populations. Compared with HPS, the significant increase in seedling growth and concomitant energy savings with LED (29% energy consumption relative to HPS) demonstrates the promise of using LED as PAR supplemental lighting for container seedling production. |
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0045-5067 |
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LoNNe @ kyba @ |
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1250 |
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Archila Bustos, M.F.; Hall, O.; Andersson, M. |
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Nighttime lights and population changes in Europe 1992-2012 |
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Journal Article |
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2015 |
Publication |
Ambio |
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Ambio |
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Remote Sensing |
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Nighttime satellite photographs of Earth reveal the location of lighting and provide a unique view of the extent of human settlement. Nighttime lights have been shown to correlate with economic development and population but little research has been done on the link between nighttime lights and population change over time. We explore whether population decline is coupled with decline in lighted area and how the age structure of the population and GDP are reflected in nighttime lights. We examine Europe between the period of 1992 and 2012 using a Geographic Information System and regression analysis. The results suggest that population decline is not coupled with decline in lighted area. Instead, human settlement extent is more closely related to the age structure of the population and to GDP. We conclude that declining populations will not necessarily lead to reductions in the extent of land development. |
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Department of Human and Economic Geography, Lund University, Solvegatan 10, 223 62, Lund, Sweden |
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English |
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0044-7447 |
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PMID:25773533 |
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LoNNe @ christopher.kyba @ |
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1138 |
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Ardavani, O.; Zerefos, S.; Doulos, L.T. |
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Redesigning the exterior lighting as part of the urban landscape: The role of transgenic bioluminescent plants in mediterranean urban and suburban lighting environments |
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Journal Article |
| Year |
2020 |
Publication |
Journal of Cleaner Production |
Abbreviated Journal |
Journal of Cleaner Production |
| Volume |
242 |
Issue |
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Pages |
118477 |
| Keywords |
Plants; Lighting |
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This research discusses the feasibility of replacing or supporting artificial lighting with Transgenic Bioluminescent Plants (TBP), as a means of minimizing light pollution, reducing electrical energy consumption and de-carbonizing urban and suburban outdoor environments, creating sustainable conditions and enriching the quality of life. Until now, no information is given about the light output of any TBPs and the question “Are the TBPs capable of producing the necessary lighting levels for exterior lighting?” is unanswered. For this reason, a new methodology is proposed for selecting and analyzing the lighting output potential of transgenic plants ted for specific climatic conditions. This methodology considers growth and reduction factors, as well as a formulae for estimating the plants’ luminous output by performing light measurements. Results show that transgenic plants in medium growth can emit a median luminous flux of up to 57 lm, a value that can definitely support low lighting requirements when used in large numbers of plants. From the lighting measurements and calculations performed in this research, the light output of the TBPs for a typical road with 5m width was found equal to 2lx. The amount of plants required was 40 at each side of the road for every 30m of streets with P6 road class. The results show that the use of bioluminescent plants can actually contribute to the reduction of energy consumption, concerning only the lighting criterium, thus creating an enormous opportunity for a new state-of- the-art market and research that could potentially minimize CO2 emissions and light pollution, improve urban and suburban microclimate, mitigate the effects of climate change, as well as provide an alternative means of lighting affecting both outdoor lighting design and landscape planning in suburban and urban settings. Moreover, further research should be applied considering also other possible ecological impacts before applying TBPs for exterior lighting applications. |
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0959-6526 |
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GFZ @ kyba @ |
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2711 |
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