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Author Depner, C.M.; Melanson, E.L.; McHill, A.W.; Wright, K.P.J.
Title Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome Type Journal Article
Year 2018 Publication Proceedings of the National Academy of Sciences of the United States of America Abbreviated Journal Proc Natl Acad Sci U S A
Volume 115 Issue 23 Pages E5390-E5399
Keywords Human Health
Abstract Proteomics holds great promise for understanding human physiology, developing health biomarkers, and precision medicine. However, how much the plasma proteome varies with time of day and is regulated by the master circadian suprachiasmatic nucleus brain clock, assessed here by the melatonin rhythm, is largely unknown. Here, we assessed 24-h time-of-day patterns of human plasma proteins in six healthy men during daytime food intake and nighttime sleep in phase with the endogenous circadian clock (i.e., circadian alignment) versus daytime sleep and nighttime food intake out of phase with the endogenous circadian clock (i.e., circadian misalignment induced by simulated nightshift work). We identified 24-h time-of-day patterns in 573 of 1,129 proteins analyzed, with 30 proteins showing strong regulation by the circadian cycle. Relative to circadian alignment, the average abundance and/or 24-h time-of-day patterns of 127 proteins were altered during circadian misalignment. Altered proteins were associated with biological pathways involved in immune function, metabolism, and cancer. Of the 30 circadian-regulated proteins, the majority peaked between 1400 hours and 2100 hours, and these 30 proteins were associated with basic pathways involved in extracellular matrix organization, tyrosine kinase signaling, and signaling by receptor tyrosine-protein kinase erbB-2. Furthermore, circadian misalignment altered multiple proteins known to regulate glucose homeostasis and/or energy metabolism, with implications for altered metabolic physiology. Our findings demonstrate the circadian clock, the behavioral wake-sleep/food intake-fasting cycle, and interactions between these processes regulate 24-h time-of-day patterns of human plasma proteins and help identify mechanisms of circadian misalignment that may contribute to metabolic dysregulation.
Address Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO 80045
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0027-8424 ISBN Medium
Area Expedition Conference
Notes PMID:29784788 Approved no
Call Number (up) GFZ @ kyba @ Serial 1916
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Author Mulvin, D.
Title Media Prophylaxis: Night Modes and the Politics of Preventing Harm Type Journal Article
Year 2018 Publication Information & Culture Abbreviated Journal Information & Culture
Volume 53 Issue 2 Pages 175-202
Keywords History; Lighting; Society
Abstract This article develops the term “media prophylaxis” to analyze the ways technologies are applied to challenges of calibrating one’s body with its environment and as defenses against endemic, human-made harms. In recent years, self-illuminated screens (like those of computers, phones, and tablets) have been identified by scientists, journalists, and concerned individuals as particularly pernicious sources of sleep-disrupting light. By tracing the history of circadian research, the effects of light on sleep patterns, and the recent appearance of software like “f.lux,” Apple’s “Night Shift,” and “Twilight,” this article shows how media-prophylactic technologies can individualize responsibility for preventing harm while simultaneously surfacing otherwise ignored forms of chronic suffering.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2164-8034 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number (up) GFZ @ kyba @ Serial 1917
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Author Levin, N.; Ali, S.; Crandall, D.
Title Utilizing remote sensing and big data to quantify conflict intensity: The Arab Spring as a case study Type Journal Article
Year 2018 Publication Applied Geography Abbreviated Journal Applied Geography
Volume 94 Issue Pages 1-17
Keywords Remote Sensing; Society; Human Health
Abstract Tracking global and regional conflict zones requires spatially explicit information in near real-time. Here, we examined the potential of remote sensing time-series data (night lights) and big data (data mining of news events and Flickr photos) for monitoring and understanding crisis development and refugee flows. We used the recent Arab Spring as a case study, and examined temporal trends in monthly time series of variables which we hypothesized to indicate conflict intensity, covering all Arab countries. Both Flickr photos and night-time lights proved as sensitive indicators for loss of economic and human capital, and news items from the Global Data on Events, Location and Tone (GDELT) project on fight events were positively correlated with actual deaths from conflicts. We propose that big data and remote sensing datasets have potential to provide disaggregated and timely data on conflicts where official statistics are lacking, offering an effective approach for monitoring geopolitical and environmental changes on Earth.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0143-6228 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number (up) GFZ @ kyba @ Serial 1918
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Author Ma, T.
Title An Estimate of the Pixel-Level Connection between Visible Infrared Imaging Radiometer Suite Day/Night Band (VIIRS DNB) Nighttime Lights and Land Features across China Type Journal Article
Year 2018 Publication Remote Sensing Abbreviated Journal Remote Sensing
Volume 10 Issue 5 Pages 723
Keywords Remote Sensing
Abstract Satellite-derived nighttime light images are increasingly used for various studies in relation to demographic, socioeconomic and urbanization dynamics because of the salient relationships between anthropogenic lighting signals at night and statistical variables at multiple scales. Owing to a higher spatial resolution and fewer over-glow and saturation effects, the new generation of nighttime light data derived from the Visible Infrared Imaging Radiometer Suite (VIIRS) day/night band (DNB), which is located on board the Suomi National Polar-Orbiting Partnership (Suomi-NPP) satellite, is expected to facilitate the performance of nocturnal luminosity-based investigations of human activity in a spatially explicit manner. In spite of the importance of the spatial connection between the VIIRS DNB nighttime light radiance (NTL) and the land surface type at a fine scale, the crucial role of NTL-based investigations of human settlements is not well understood. In this study, we investigated the pixel-level relationship between the VIIRS DNB-derived NTL, a Landsat-derived land-use/land-cover dataset, and the map of point of interest (POI) density over China, especially with respect to the identification of artificial surfaces in urban land. Our estimates suggest that notable differences in the NTL between urban (man-made) surfaces and other types of land surfaces likely allow us to spatially identify most of the urban pixels with relatively high radiance values in VIIRS DNB images. Our results also suggest that current nighttime light data have a limited capability for detecting rural residential areas and explaining pixel-level variations in the POI density at a large scale. Moreover, the impact of non-man-made surfaces on the partitioned results appears inevitable because of the spatial heterogeneity of human settlements and the nature of remotely sensed nighttime light data. Using receiver operating characteristic (ROC) curve-based analysis, we obtained optimal thresholds of the nighttime light radiance, by equally weighting the sensitivity and specificity of the identification results, for extracting the nationwide distribution of lighted urban man-made pixels from the 2015 annual composite of VIIRS DNB data. Our findings can provide the basic knowledge needed for the further application of current nighttime light data to investigate spatiotemporal patterns in human settlements.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2072-4292 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number (up) GFZ @ kyba @ Serial 1919
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Author Bowne, D.R.; Cosentino, B.J.; Anderson, L.J.; Bloch, C.P.; Cooke, S.; Crumrine, P.W.; Dallas, J.; Doran, A.; Dosch, J.J.; Druckenbrod, D.L.; Durtsche, R.D.; Garneau, D.; Genet, K.S.; Fredericksen, T.S.; Kish, P.A.; Kolozsvary, M.B.; Kuserk, F.T.; Lindquist, E.S.; Mankiewicz, C.; March, J.G.; Muir, T.J.; Murray, K.G.; Santulli, M.N.; Sicignano, F.J.; Smallwood, P.D.; Urban, R.A.; Winnett-Murray, K.; Zimmermann, C.R.
Title Effects of urbanization on the population structure of freshwater turtles across the United States Type Journal Article
Year 2018 Publication Conservation Biology : the Journal of the Society for Conservation Biology Abbreviated Journal Conserv Biol
Volume 32 Issue 5 Pages 1150-1161
Keywords Animals; Remote Sensing
Abstract Landscape-scale alterations that accompany urbanization may negatively affect the population structure of wildlife species such as freshwater turtles. Changes to nesting sites and higher mortality rates due to vehicular collisions and increased predator populations may particularly affect immature turtles and mature female turtles. We hypothesized that the proportions of adult female and immature turtles in a population will negatively correlate with landscape urbanization. As a collaborative effort of the Ecological Research as Education Network (EREN), we sampled freshwater turtle populations in 11 states across the central and eastern United States. Contrary to expectations, we found a significant positive relationship between proportions of mature female painted turtles (Chrysemys picta) and urbanization. We did not detect a relationship between urbanization and proportions of immature turtles. Urbanization may alter the thermal environment of nesting sites such that more females are produced as urbanization increases. Our approach of creating a collaborative network of scientists and students at undergraduate institutions proved valuable in terms of testing our hypothesis over a large spatial scale while also allowing students to gain hands-on experience in conservation science. This article is protected by copyright. All rights reserved.
Address Department of Biology, Rogers State University, 1701 W. Will Rogers Boulevard, Claremore, OK 74017, U.S.A
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0888-8892 ISBN Medium
Area Expedition Conference
Notes PMID:29781169 Approved no
Call Number (up) GFZ @ kyba @ Serial 1920
Permanent link to this record