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Author |
Reddy, A.B.; O'Neill, J.S. |
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Title |
Healthy clocks, healthy body, healthy mind |
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Journal Article |
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Year |
2010 |
Publication |
Trends in Cell Biology |
Abbreviated Journal |
Trends Cell Biol |
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Volume |
20 |
Issue |
1 |
Pages |
36-44 |
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Keywords  |
Aging; Animals; Cell Cycle; *Circadian Rhythm; Humans; Neoplasms/genetics/metabolism; Signal Transduction |
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Abstract |
Circadian rhythms permeate mammalian biology. They are manifested in the temporal organisation of behavioural, physiological, cellular and neuronal processes. Whereas it has been shown recently that these approximately 24-hour cycles are intrinsic to the cell and persist in vitro, internal synchrony in mammals is largely governed by the hypothalamic suprachiasmatic nuclei that facilitate anticipation of, and adaptation to, the solar cycle. Our timekeeping mechanism is deeply embedded in cell function and is modelled as a network of transcriptional and/or post-translational feedback loops. Concurrent with this, we are beginning to understand how this ancient timekeeper interacts with myriad cell systems, including signal transduction cascades and the cell cycle, and thus impacts on disease. An exemplary area where this knowledge is rapidly expanding and contributing to novel therapies is cancer, where the Period genes have been identified as tumour suppressors. In more complex disorders, where aetiology remains controversial, interactions with the clockwork are only now starting to be appreciated. |
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Department of Clinical Neurosciences, University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 OQQ, UK. abr20@cam.ac.uk |
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0962-8924 |
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PMID:19926479; PMCID:PMC2808409 |
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no |
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Call Number |
IDA @ john @ |
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133 |
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Author |
Stark, H.; Brown, S.S.; Wong, K.W.; Stutz, J.; Elvidge, C.D.; Pollack, I.B.; Ryerson, T.B.; Dube, W.P.; Wagner, N.L.; Parrish, D.D. |
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Title |
City lights and urban air |
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Journal Article |
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Year |
2011 |
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Nature Geoscience |
Abbreviated Journal |
Nature Geosci |
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Volume |
4 |
Issue |
11 |
Pages |
730-731 |
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Keywords |
air pollution; light pollution; light at night |
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NOAA Earth System Research Laboratory, Chemical Sciences Division, 325 Broadway, R/CSD 7, Boulder, Colorado 80305, USA |
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1752-0894 |
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IDA @ john @ |
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270 |
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Author |
Rayleigh, L. |
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Title |
Some Recent Work on the Light of the Night Sky1 |
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Journal Article |
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Year |
1928 |
Publication |
Nature |
Abbreviated Journal |
Nature |
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Volume |
122 |
Issue |
3070 |
Pages |
315-317 |
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Keywords |
Airglow; Natural Sky Brightness |
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T is now well known that the light of the night sky has little in common with the day sky. When the sun is 18° below the horizon, and the moon also below the horizon, night conditions may be considered to be established. A clear sky is of course necessary for the study of the luminosity. Unlike the day sky, it is found to exhibit very little polarisation. The intensity is considerably below the threshold of colour vision, and subjective impressions about its colour, which is sometimes described by imaginative writers as blue, have no basis in reality. |
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0028-0836 |
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GFZ @ kyba @ |
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3123 |
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Su, Y.; Yue, J.; Liu, X.; Miller, S.D.; Ш, W.C.S.; Smith, S.M.; Guo, D.; Guo, S. |
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Title |
Mesospheric Bore Observations Using Suomi-NPP VIIRS DNB during 2013–2017 |
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Journal Article |
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2018 |
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Remote Sensing |
Abbreviated Journal |
Remote Sensing |
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Volume |
10 |
Issue |
12 |
Pages |
1935 |
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Keywords |
Airglow; Remote Sensing |
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This paper reports mesospheric bore events observed by Day/Night Band (DNB) of the Visible/Infrared Imaging Radiometer Suite (VIIRS) on the National Oceanic and Atmospheric Administration/National Aeronautics and Space Administration (NOAA/NASA) Suomi National Polar-orbiting Partnership (NPP) environmental satellite over five years (2013–2017). Two types of special mesospheric bore events were observed, enabled by the wide field of view of VIIRS: extremely wide bores (>2000 km extension perpendicular to the bore propagation direction), and those exhibiting more than 15 trailing crests and troughs. A mesospheric bore event observed simultaneously from space and ground was investigated in detail. DNB enables the preliminary global observation of mesospheric bores for the first time. DNB mesospheric bores occurred more frequently in March, April and May. Their typical lengths are between 300 km and 1200 km. The occurrence rate of bores at low latitudes is higher than that at middle latitudes. Among the 61 bore events, 39 events occurred in the tropical region (20°S–20°N). The high occurrence rate of mesospheric bores during the spring months in the tropical region coincides with the reported seasonal and latitudinal variations of mesospheric inversion layers. |
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2072-4292 |
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GFZ @ kyba @ |
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2128 |
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Holzhauer S.I.J.; Franke S.; Kyba C.C.M.; Manfrin A.; Klenke R.; Voigt C.C.; Lewanzik D.; Oehlert M.; Monaghan M.T.; Schneider S.; Heller S.; Kuechly H.; Brüning A.; Honnen A.-C.; Hölker F. |
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Title |
Out of the Dark: Establishing a Large-Scale Field Experiment to Assess the Effects of Artificial Light at Night on Species and Food Webs |
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Journal Article |
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Year |
2015 |
Publication |
Sustainability |
Abbreviated Journal |
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Volume |
7 |
Issue |
11 |
Pages |
15593-15616 |
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Keywords |
ALAN; artificial light at night; ecosystems; freshwater; light pollution; loss of the night; photometric characterization; riparian; Verlust der Nacht |
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Abstract |
Artificial light at night (ALAN) is one of the most obvious hallmarks of human presence in an ecosystem. The rapidly increasing use of artificial light has fundamentally transformed nightscapes throughout most of the globe, although little is known about how ALAN impacts the biodiversity and food webs of illuminated ecosystems. We developed a large-scale experimental infrastructure to study the effects of ALAN on a light-naïve, natural riparian (i.e., terrestrial-aquatic) ecosystem. Twelve street lights (20 m apart) arranged in three rows parallel to an agricultural drainage ditch were installed on each of two sites located in a grassland ecosystem in northern Germany. A range of biotic, abiotic, and photometric data are collected regularly to study the short- and long-term effects of ALAN on behavior, species interactions, physiology, and species composition of communities. Here we describe the infrastructure setup and data collection methods, and characterize the study area including photometric measurements. None of the measured parameters differed significantly between sites in the period before illumination. Results of one short-term experiment, carried out with one site illuminated and the other acting as a control, demonstrate the attraction of ALAN by the immense and immediate increase of insect catches at the lit street lights. The experimental setup provides a unique platform for carrying out interdisciplinary research on sustainable lighting. |
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Address |
Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB), Müggelseedamm 301/310, 12587 Berlin, Germany; holzhauer(at)igb-berlin.de |
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MDPI |
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English |
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English |
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LoNNe @ schroer @ |
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1305 |
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