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Author Rahman, S.A.; Bibbo, C.; Olcese, J.; Czeisler, C.A.; Robinson, J.N.; Klerman, E.B.
Title Relationship between endogenous melatonin concentrations and uterine contractions in late third trimester of human pregnancy Type Journal Article
Year 2019 Publication Journal of Pineal Research Abbreviated Journal J Pineal Res
Volume in press Issue Pages
Keywords Human Health
Abstract In humans, circulating levels of the hormone melatonin and the initiation of spontaneous labor are both higher at night than during the day. Since activation of uterine melatonin receptors can stimulate human in vitro uterine contractions and these receptors are only expressed on the uterine tissue of women in labor, we hypothesized that circulating melatonin concentrations would affect uterine contractions in vivo. We evaluated the impact of light-induced modulation of melatonin secretion on uterine contractions in women during late third-trimester (~36-39 weeks) of pregnancy in two inpatient protocols. We found a significant (p<0.05) positive linear association between circulating melatonin concentrations and the number of uterine contractions under both protocols. On average, uterine contractions increased between 1.4 to 2.1 contractions per 30 minutes for every 10 pg/ml*h increase in melatonin concentration. These findings have both basic science and clinical implications for pregnant women, since endogenous melatonin levels and melatonin receptor activity can be altered by light and/or pharmaceutical agents. This article is protected by copyright. All rights reserved.
Address Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0742-3098 ISBN Medium
Area Expedition Conference
Notes (down) PMID:30739346 Approved no
Call Number GFZ @ kyba @ Serial 2203
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Author Suter, P.M.
Title Gedanken zu Licht und Schlaf [Thoughts about Light and Sleep] Type Journal Article
Year 2019 Publication Praxis Abbreviated Journal Praxis (Bern 1994)
Volume 108 Issue 2 Pages 139-143
Keywords Commentary; Human Health
Abstract Many aspects of health and disease are mainly determined by the constant change between light and darkness during a solar day. The resulting physiological rhythms correspond to the circadian rhythm, which was one of the most central drivers in the evolution of humans. However, over the last 20-30 years, these natural rhythms of the change of light and darkness are being increasingly ignored by modern societies. It is well known that these rhythms are modulators of many physiological pathways and any desynchronization or misalignment will activate different pathophysiological pathways, which contribute to the risk of chronic diseases. Light pollution by widespread illumination of our environment and the night sky and uncontrolled man-made use of any light source plays a key role in the pathogenesis of sleep disturbances. Blue light exposure in the evening from any artificial light source (especially from electronic device screens) is of special relevance in this context. In this article a few key facts concerning light, sleep and diseases are presented. We should by all means account for the effects of light and darkness and stop any further light pollution.

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Unser Leben wird durch die sich rhythmisch abwechselnde Helligkeit und Dunkelheit während eines «Solartages» bestimmt, was die Grundlage für den zirkadianen Rhythmus darstellt. Dies war Millionen von Jahren so, und erst in den vergangenen 20–30 Jahren wird diese Rhythmik infolge einer ubiquitären Verwendung von Licht zunehmend ignoriert. Die zirkadiane Rhythmik stellt allerdings eine der zentralsten Determinanten für Gesundheit und Krankheit dar, und man weiss, dass eine Abweichung vom bzw. Desynchronisation des normalen Rhythmus ein hohes pathophysiologisches Potenzial hat und in der Pathogenese der meisten chronischen Erkrankungen eine zentrale Rolle spielt. Die exzessive Beleuchtung der Umgebung und des Nachthimmels wird als Lichtverschmutzung oder «Light Pollution» bezeichnet, die sich unter anderem auch in Schlafstörungen manifestiert. Dabei darf im Besonderen das blaue Licht aus künstlichen Lichtquellen und Bildschirmen am Abend bei der Entstehung von Schlafstörungen nicht ausser Betracht gelassen werden. In diesem Artikel werden einige Aspekte zum Thema Licht, Schlaf und Gesundheit in Erinnerung gerufen und praxisrelevante Zusammenhänge aufgezeigt. Eine Kontrolle der Lichtverschmutzung ist dringend angezeigt.
Address 1 Medizinische Poliklinik, Klinik und Poliklinik fur Innere Medizin, Universitatsspital Zurich
Corporate Author Thesis
Publisher Place of Publication Editor
Language German Summary Language Original Title Mach nicht zu viel <<blau>>
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1661-8157 ISBN Medium
Area Expedition Conference
Notes (down) PMID:30722742 Approved no
Call Number GFZ @ kyba @ Serial 2205
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Author Durrant, J.; Green, M.P.; Jones, T.M.
Title Dim artificial light at night reduces the cellular immune response of the black field cricket, Teleogryllus commodus Type Journal Article
Year 2019 Publication Insect Science Abbreviated Journal Insect Sci
Volume in press Issue Pages
Keywords Animals
Abstract A functioning immune system is crucial for protection against disease and illness, yet increasing evidence suggests that species living in urban areas could be suffering from immune suppression, due to the presence of artificial light at night (ALAN). This study examined the effects of ecologically relevant levels of ALAN on three key measures of immune function (haemocyte concentration, lytic activity, and phenoloxidase activity) using a model invertebrate species, the Australian black field cricket, Teleogryllus commodus. We reared crickets under an ecologically relevant daily light-cycle consisting of 12 hr bright daylight (2600 lx) followed by either 12 h darkness (0 lx) or dim environmentally-relevant ALAN (1, 10, 100 lx), and then assessed immune function at multiple time points throughout adult life using haemolymph samples. We found that the presence of ALAN had a clear negative effect on haemocytes, while the effects on lytic activity and phenoloxidase activity were more complex or largely unaffected by ALAN. Furthermore, the effects of lifelong exposure to ALAN of 1 lx were comparable to those of 10 and 100 lx. Our data suggest that the effects of ALAN could be large and widespread, and such reductions in the core immune response of individuals will likely have greater consequences for fitness and survival under more malign conditions, such as those of the natural environment. This article is protected by copyright. All rights reserved.
Address The School of BioSciences, Faculty of Science, University of Melbourne, Victoria, 3010, Australia
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1672-9609 ISBN Medium
Area Expedition Conference
Notes (down) PMID:30720239 Approved no
Call Number GFZ @ kyba @ Serial 2196
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Author Jechow, A.; Holker, F.; Kyba, C.C.M.
Title Using all-sky differential photometry to investigate how nocturnal clouds darken the night sky in rural areas Type Journal Article
Year 2019 Publication Scientific Reports Abbreviated Journal Sci Rep
Volume 9 Issue 1 Pages 1391
Keywords Skyglow; differential photometry; clouds; sky brightness
Abstract Artificial light at night has affected most of the natural nocturnal landscapes worldwide and the subsequent light pollution has diverse effects on flora, fauna and human well-being. To evaluate the environmental impacts of light pollution, it is crucial to understand both the natural and artificial components of light at night under all weather conditions. The night sky brightness for clear skies is relatively well understood and a reference point for a lower limit is defined. However, no such reference point exists for cloudy skies. While some studies have examined the brightening of the night sky by clouds in urban areas, the published data on the (natural) darkening by clouds is very sparse. Knowledge of reference points for the illumination of natural nocturnal environments however, is essential for experimental design and ecological modeling to assess the impacts of light pollution. Here we use differential all-sky photometry with a commercial digital camera to investigate how clouds darken sky brightness at two rural sites. The spatially resolved data enables us to identify and study the nearly unpolluted parts of the sky and to set an upper limit on ground illumination for overcast nights at sites without light pollution.
Address GFZ German Research Centre for Geosciences, Remote Sensing, Telegrafenberg, 14473, Potsdam, Germany
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2045-2322 ISBN Medium
Area Expedition Conference
Notes (down) PMID:30718668; PMCID:PMC6361923 Approved no
Call Number IDA @ john @ Serial 2188
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Author Farghly, M.F.A.; Mahrose, K.M.; Rehman, Z.U.; Yu, S.; Abdelfattah, M.G.; El-Garhy, O.H.
Title Intermittent lighting regime as a tool to enhance egg production and eggshell thickness in Rhode Island Red laying hens Type Journal Article
Year 2019 Publication Poultry Science Abbreviated Journal Poult Sci
Volume in press Issue Pages
Keywords Animals
Abstract Influences of intermittent light regime as a tool to enhance egg production, egg quality, and blood parameters of laying hens were investigated. A total of 270 hens of Rhode Island Red (during 20 to 36 wk of age) were used to investigate the effects of intermittent light regime in completely randomized design. The birds were divided into 3 equal groups (6 replicates of 15 birds each) and housed in floor pens. The first group was served as non-treated control (C) and was exposed to continuous and constant light for 16 h light/day throughout the experimental period. Whereas, birds of the other groups were exposed to intermittent lights for 20 min/h + 40 min of constant light (T1; FLASH20) and 40 min/h + 20 min of constant light (T2; FLASH40) during the 16 h of light period. Hens of T1 group showed significantly (P </= 0.05) the highest concentration of total antioxidant capacity and the lowest one of malondialdehyde in comparison with the other groups. Hens of T1 group had significantly (P </= 0.05) the greatest egg laying rate and egg mass in comparison with the other counterparts. Feed consumption was similar in the groups under study. Hens exposed to FLASH20 had the lowest (P </= 0.05) FCR when compared with the other treatments. Eggs produced from hens exposed to FLASH20 had the highest value of shell thickness followed by the control and then that of those exposed to FLASH40. There were insignificant differences among the treatments in body weight of hens and all of other egg quality and egg problem traits. In conclusion, intermittent light regime of 20 min/h was the most efficient in comparison with the other ones. Finally, intermittent light regime of 20 min/h during laying period (during 20 to 36 wk of age) is highly recommended.
Address Animal Production Department, Faculty of Agriculture, Benha University, Qalubia, Egypt
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0032-5791 ISBN Medium
Area Expedition Conference
Notes (down) PMID:30715501 Approved no
Call Number GFZ @ kyba @ Serial 2206
Permanent link to this record