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Faraji, H.; MacLean, W.J. |
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Title |
CCD noise removal in digital images |
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Journal Article |
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Year |
2006 |
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IEEE Transactions on Image Processing |
Abbreviated Journal |
IEEE Trans. on Image Process. |
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15 |
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9 |
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2676-2685 |
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Remote Sensing |
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1057-7149 |
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LoNNe @ kagoburian @ |
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935 |
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Coffin, D. |
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Dave Coffinś DCRAW. |
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2006 |
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LoNNe @ kagoburian @ |
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916 |
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Cinzano, P.; Falchi, F.; Elvidge, C. |
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Recent progresses on a second world atlas of the night-sky brightness--LPTRAN/LPDART realistic models, tomography of light pollution, accurate validation methods and extended satellite data analysis |
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Conference Article |
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2006 |
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Meeting of the IAU Comm |
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50 |
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Remote Sensing |
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LoNNe @ kagoburian @ |
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914 |
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Stevens, R.G. |
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Artificial lighting in the industrialized world: circadian disruption and breast cancer |
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Year |
2006 |
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Cancer Causes & Control : CCC |
Abbreviated Journal |
Cancer Causes Control |
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17 |
Issue |
4 |
Pages |
501-507 |
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Keywords |
Human Health; Alcohol Drinking/adverse effects; Animals; Breast Neoplasms/*etiology; Chronobiology Disorders/*etiology/physiopathology; Circadian Rhythm; Developing Countries; Female; Humans; Lighting/*adverse effects; Melatonin/metabolism; Risk Factors; Suprachiasmatic Nucleus/physiopathology |
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Breast cancer risk is high in industrialized societies, and increases as developing countries become more Westernized. The reasons are poorly understood. One possibility is circadian disruption from aspects of modern life, in particular the increasing use of electric power to light the night, and provide a sun-free environment during the day inside buildings. Circadian disruption could lead to alterations in melatonin production and in changing the molecular time of the circadian clock in the suprachiasmatic nuclei (SCN). There is evidence in humans that the endogenous melatonin rhythm is stronger for persons in a bright-day environment than in a dim-day environment; and the light intensity necessary to suppress melatonin at night continues to decline as new experiments are done. Melatonin suppression can increase breast tumorigenesis in experimental animals, and altering the endogenous clock mechanism may have downstream effects on cell cycle regulatory genes pertinent to breast tissue development and susceptibility. Therefore, maintenance of a solar day-aligned circadian rhythm in endogenous melatonin and in clock gene expression by exposure to a bright day and a dark night, may be a worthy goal. However, exogenous administration of melatonin in an attempt to achieve this goal may have an untoward effect given that pharmacologic dosing with melatonin has been shown to phase shift humans depending on the time of day it's given. Exogenous melatonin may therefore contribute to circadian disruption rather than alleviate it. |
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University of Connecticut Health Center, Farmington, CT 06030-6325, USA. bugs@neuron.uchc.edu |
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0957-5243 |
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PMID:16596303 |
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LoNNe @ kagoburian @ |
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818 |
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Srinivasan, V.; Smits, M.; Spence, W.; Lowe, A.D.; Kayumov, L.; Pandi-Perumal, S.R.; Parry, B.; Cardinali, D.P. |
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Title |
Melatonin in mood disorders |
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Journal Article |
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2006 |
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The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry |
Abbreviated Journal |
World J Biol Psychiatry |
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7 |
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3 |
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138-151 |
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Human Health; Antidepressive Agents/therapeutic use; Biological Markers/blood; Bipolar Disorder/diagnosis/drug therapy/*physiopathology; Circadian Rhythm/drug effects/physiology; Depressive Disorder/diagnosis/drug therapy/*physiopathology; Depressive Disorder, Major/diagnosis/drug therapy/physiopathology; Humans; Melatonin/*blood/therapeutic use; Phototherapy; Seasonal Affective Disorder/diagnosis/physiopathology; Sleep Disorders, Circadian Rhythm/diagnosis/drug therapy/physiopathology; Treatment Outcome |
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The cyclic nature of depressive illness, the diurnal variations in its symptomatology and the existence of disturbed sleep-wake and core body temperature rhythms, all suggest that dysfunction of the circadian time keeping system may underlie the pathophysiology of depression. As a rhythm-regulating factor, the study of melatonin in various depressive illnesses has gained attention. Melatonin can be both a 'state marker' and a 'trait marker' of mood disorders. Measurement of melatonin either in saliva or plasma, or of its main metabolite 6-sulfatoxymelatonin in urine, have documented significant alterations in melatonin secretion in depressive patients during the acute phase of illness. Not only the levels but also the timing of melatonin secretion is altered in bipolar affective disorder and in patients with seasonal affective disorder (SAD). A phase delay of melatonin secretion takes place in SAD, as well as changes in the onset, duration and offset of melatonin secretion. Bright light treatment, that suppresses melatonin production, is effective in treating bipolar affective disorder and SAD, winter type. This review discusses the role of melatonin in the pathophysiology of bipolar disorder and SAD. |
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Department of Physiology, School of Medical Sciences, University Sains Malaysia, Kubang Kerian, Kota Bharu, Kelantan |
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1562-2975 |
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PMID:16861139 |
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LoNNe @ kagoburian @ |
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816 |
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