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Author Cajochen, C.; Jud, C.; Munch, M.; Kobialka, S.; Wirz-Justice, A.; Albrecht, U.
Title Evening exposure to blue light stimulates the expression of the clock gene PER2 in humans Type Journal Article
Year 2006 Publication The European Journal of Neuroscience Abbreviated Journal Eur J Neurosci
Volume (up) 23 Issue 4 Pages 1082-1086
Keywords Human Health; Adult; Color; Darkness; Dose-Response Relationship, Radiation; Female; Gene Expression/*radiation effects; Humans; *Light; Male; Melatonin/metabolism; Mucous Membrane/metabolism/radiation effects; Nuclear Proteins/genetics/*metabolism; Period Circadian Proteins; Transcription Factors/genetics/*metabolism
Abstract We developed a non-invasive method to measure and quantify human circadian PER2 gene expression in oral mucosa samples and show that this gene oscillates in a circadian (= about a day) fashion. We also have the first evidence that induction of human PER2 expression is stimulated by exposing subjects to 2 h of light in the evening. This increase in PER2 expression was statistically significant in comparison to a non-light control condition only after light at 460 nm (blue) but not after light exposure at 550 nm (green). Our results indicate that the non-image-forming visual system is involved in human circadian gene expression. The demonstration of a functional circadian machinery in human buccal samples and its response to light opens the door for investigation of human circadian rhythms at the gene level and their associated disorders.
Address Centre for Chronobiology, Psychiatric University Clinics, University of Basel, CH-4025 Basel, Switzerland. christian.cajochen@unibas.ch
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0953-816X ISBN Medium
Area Expedition Conference
Notes PMID:16519674 Approved no
Call Number LoNNe @ kagoburian @ Serial 727
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Author Fouquet, R.; Pearson, P.J.
Title Seven centuries of energy services: The price and use of light in the United Kingdom (1300-2000) Type Journal Article
Year 2006 Publication Energy Journal Abbreviated Journal
Volume (up) 27 Issue Pages 139-177
Keywords Energy; Economics
Abstract Before the mid-eighteenth century, most people lived in near-complete

darkness except in the presence of sunlight and moonlight. Since then, the provision

of artificial light has been revolutionised by a series of innovations in appliances,

fuels, infrastructures and institutions that have enabled the growing demands of

economic development for artificial light to be met at dramatically lower costs:

by the year 2000, while United Kingdom GDP per capita was 15 times its 1800

value, lighting services cost less than one three thousandth of their 1800 value,

per capita use was 6,500 times greater and total lighting consumption was 25,000

times higher than in 1800. The economic history of light shows how focussing on

developments in energy service provision rather than simply on energy use and

prices can reveal the ‘true’ declines in costs, enhanced levels of consumption

and welfare gains that have been achieved. While emphasising the value of past

experience, the paper also warns against the dangers of over-reliance on past

trends for the long-run forecasting of energy consumption given the potential for the

introduction of new technologies and fuels, and for rebound and saturation effects.
Address
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Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
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ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number LoNNe @ christopher.kyba @ Serial 441
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Author Amaral, S.; Monteiro, A.M.V.; Camara, G.; Quintanilha, J.A.
Title DMSP/OLS night-time light imagery for urban population estimates in the Brazilian Amazon Type Journal Article
Year 2006 Publication International Journal of Remote Sensing Abbreviated Journal International Journal of Remote Sensing
Volume (up) 27 Issue 5 Pages 855-870
Keywords Remote Sensing
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0143-1161 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number LoNNe @ kagoburian @ Serial 701
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Author Anisimov, V. N.
Title Light pollution, reproductive function and cancer risk Type Journal Article
Year 2006 Publication Neuroendocrinology Letters Abbreviated Journal
Volume (up) 27 Issue 1-2 Pages 35-52
Keywords Human Health
Abstract At present, light pollution (exposure to light-at-night) both in the form of occupational exposure during night work and as a personal choice and life style, is experienced by numerous night-active members of our society. Disruption of the circadian rhythms induced by light pollution has been associated with cancer in humans. There are epidemiological evidences of increased breast and colon cancer risk in shift workers. An inhibition of the pineal gland function with exposure to the constant light (LL) regimen promoted carcinogenesis whereas the light deprivation inhibits the carcinogenesis. Treatment with pineal indole hormone melatonin inhibits carcinogenesis in pinealectomized rats or animals kept at the standard light/dark regimen (LD) or at the LL regimen. These observations might lead to use melatonin for cancer prevention in groups of humans at risk of light pollution.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number LoNNe @ kagoburian @ Serial 703
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Author Stoffels, W.W.
Title Gravity's pull on arc lamp efficiency Type Journal Article
Year 2006 Publication Europhysics News Abbreviated Journal Europhysics News
Volume (up) 37 Issue 6 Pages 35-38
Keywords Lighting; physics; plasma; gravity; lighting technology; lighting physics; metal halide; hypergravity; microgravity
Abstract (none)
Address Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven, Netherlands; w.w.stoffels(at)tue.nl
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0531-7479 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number IDA @ john @ Serial 1367
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