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Author Jones, A.; Noll, S.; Kausch, W.; Szyszka, C.; Kimeswenger, S.
Title An advanced scattered moonlight model for Cerro Paranal Type Journal Article
Year 2013 Publication Astronomy & Astrophysics Abbreviated Journal (up) A&A
Volume 560 Issue Pages A91
Keywords Moonlight
Abstract The largest natural source of light at night is the Moon, and it is the major contributor to the astronomical sky background. Being able to accurately predict the sky background, including scattered moonlight is important for scheduling astronomical observations. We have developed an improved scattered moonlight model, in which the components are computed with a better physical understanding as opposed to the simple empirical fit in the frequently used photometric model of Krisciunas & Schaefer (1991, PASP, 103, 1033). Our spectroscopic model can better trace the spectral trends of scattered moonlight for any position of the Moon and target observation. This is the first scattered moonlight model that we know of which is this physical and versatile. We have incorporated an observed solar spectrum, accurate lunar albedo fit, and elaborate scattering and absorption calculations that include scattering off of molecules and aerosols. It was designed for Cerro Paranal, but can be modified for any location with known atmospheric properties. Throughout the optical range, the uncertainty is less than 20%. This advanced scattered moonlight model can predict the amount of scattered moonlight for any given geometry of the Moon and target, and lunar phase for the entire optical spectrum.
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Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0004-6361 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number LoNNe @ kyba @ Serial 1461
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Author Bullough, J.D.; Donnell, E.T.; Rea, M.S.
Title To illuminate or not to illuminate: roadway lighting as it affects traffic safety at intersections Type Journal Article
Year 2013 Publication Accident; Analysis and Prevention Abbreviated Journal (up) Accid Anal Prev
Volume 53 Issue Pages 65-77
Keywords Lighting; Accident Prevention/*methods; Accidents, Traffic/*prevention & control/psychology/statistics & numerical data; Cross-Sectional Studies; *Environment Design; Humans; *Lighting; Minnesota; Models, Statistical; Photoperiod; Psychomotor Performance; Regression Analysis; Safety/statistics & numerical data; Visual Perception
Abstract A two-pronged effort to quantify the impact of lighting on traffic safety is presented. In the statistical approach, the effects of lighting on crash frequency for different intersection types in Minnesota were assessed using count regression models. The models included many geometric and traffic control variables to estimate the association between lighting and nighttime and daytime crashes and the resulting night-to-day crash ratios. Overall, the presence of roadway intersection lighting was found to be associated with an approximately 12% lower night-to-day crash ratio than unlighted intersections. In the parallel analytical approach, visual performance analyses based on roadway intersection lighting practices in Minnesota were made for the same intersection types investigated in the statistical approach. The results of both approaches were convergent, suggesting that visual performance improvements from roadway lighting could serve as input for predicting improvements in crash frequency. A provisional transfer function allows transportation engineers to evaluate alternative lighting systems in the design phase so selections based on expected benefits and costs can be made.
Address Lighting Research Center, Rensselaer Polytechnic Institute, 21 Union Street, Troy, NY 12180, USA
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0001-4575 ISBN Medium
Area Expedition Conference
Notes PMID:23377085 Approved no
Call Number LoNNe @ kagoburian @ Serial 627
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Author Brainard, G.C.; Coyle, W.; Ayers, M.; Kemp, J.; Warfield, B.; Maida, J.; Bowen, C.; Bernecker, C.; Lockley, S.W.; Hanifin, J.P.
Title Solid-state lighting for the International Space Station: Tests of visual performance and melatonin regulation Type Journal Article
Year 2013 Publication Acta Astronautica Abbreviated Journal (up) Acta Astronautica
Volume 92 Issue 1 Pages 21-28
Keywords Human Health; Lighting
Abstract The International Space Station (ISS) uses General Luminaire Assemblies (GLAs) that house fluorescent lamps for illuminating the astronauts' working and living environments. Solid-state light emitting diodes (LEDs) are attractive candidates for replacing the GLAs on the ISS. The advantages of LEDs over conventional fluorescent light sources include lower up-mass, power consumption and heat generation, as well as fewer toxic materials, greater resistance to damage and long lamp life. A prototype Solid-State Lighting Assembly (SSLA) was developed and successfully installed on the ISS. The broad aim of the ongoing work is to test light emitted by prototype SSLAs for supporting astronaut vision and assessing neuroendocrine, circadian, neurobehavioral and sleep effects. Three completed ground-based studies are presented here including experiments on visual performance, color discrimination, and acute plasma melatonin suppression in cohorts of healthy, human subjects under different SSLA light exposure conditions within a high-fidelity replica of the ISS Crew Quarters (CQ). All visual tests were done under indirect daylight at 201 lx, fluorescent room light at 531 lx and 4870 K SSLA light in the CQ at 1266 lx. Visual performance was assessed with numerical verification tests (NVT). NVT data show that there are no significant differences in score (F=0.73, p=0.48) or time (F=0.14, p=0.87) for subjects performing five contrast tests (10%–100%). Color discrimination was assessed with Farnsworth-Munsell 100 Hue tests (FM-100). The FM-100 data showed no significant differences (F=0.01, p=0.99) in color discrimination for indirect daylight, fluorescent room light and 4870 K SSLA light in the CQ. Plasma melatonin suppression data show that there are significant differences (F=29.61, p<0.0001) across the percent change scores of plasma melatonin for five corneal irradiances, ranging from 0 to 405 &#956;W/cm2 of 4870 K SSLA light in the CQ (0–1270 lx). Risk factors for the health and safety of astronauts include disturbed circadian rhythms and altered sleep–wake patterns. These studies will help determine if SSLA lighting can be used both to support astronaut vision and serve as an in-flight countermeasure for circadian desynchrony, sleep disruption and cognitive performance deficits on the ISS.
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Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-5765 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number LoNNe @ kyba @ Serial 1533
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Author van der Burght, B.W.; Hansen, M.; Olsen, J.; Zhou, J.; Wu, Y.; Nissen, M.H.; Sparrow, J.R.
Title Early changes in gene expression induced by blue light irradiation of A2E-laden retinal pigment epithelial cells Type Journal Article
Year 2013 Publication Acta Ophthalmologica Abbreviated Journal (up) Acta Ophthalmol
Volume 91 Issue 7 Pages e537-45
Keywords Apoptosis; Cell Line; Cell Survival; Gene Expression Regulation/*physiology; Humans; Light; Lipofuscin/genetics; Oligonucleotide Array Sequence Analysis; Principal Component Analysis; Pyridinium Compounds; RNA, Messenger/genetics; Real-Time Polymerase Chain Reaction; Retinal Pigment Epithelium/metabolism/pathology/*radiation effects; Retinoids/*genetics; Transcriptome; A2e; age-related macular degeneration; apoptosis; complement cascade; gene expression; retinal pigment epithelial cells; blue light; retinal pigment epithelial; epigenetics
Abstract PURPOSE: Accumulation of bisretinoids as lipofuscin in retinal pigment epithelial (RPE) cells is implicated in the pathogenesis of some blinding diseases including age-related macular degeneration (AMD). To identify genes whose expression may change under conditions of bisretinoid accumulation, we investigated the differential gene expression in RPE cells that had accumulated the lipofuscin fluorophore A2E and were exposed to blue light (430 nm). METHODS: A2E-laden RPE cells were exposed to blue light (A2E/430 nm) at various time intervals. Cell death was quantified using Dead Red staining, and RNA levels for the entire genome was determined using DNA microarrays (Affymetrix GeneChip Human Genome 2.0 Plus). Array results for selected genes were confirmed by real-time reverse-transcriptase polymerase chain reaction. RESULTS: Principal component analysis revealed that the A2E-laden RPE cells irradiated with blue light were clearly distinguishable from the control samples. We found differential regulation of genes belonging to the following functional groups: transcription factors, stress response, apoptosis and immune response. Among the last mentioned were downregulation of four genes that coded for proteins that have an inhibitory effect on the complement cascade: (complement factor H, complement factor H-related 1, complement factor I and vitronectin) and of two belonging to the classical pathway (complement component 1, s subcomponent and complement component 1, r subcomponent). CONCLUSION: This study demonstrates that blue light irradiation of A2E-laden RPE cells can alter the transcription of genes belonging to different functional pathways including stress response, apoptosis and the immune response. We suggest that these molecules may be associated to the pathogenesis of AMD and can potentially serve as future therapeutic targets.
Address Department of International Health, Immunology and Microbiology, Eye Research Unit, University of Copenhagen, Copenhagen, DenmarkDepartment of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, DenmarkDepartment of Ophthalmology, Columbia University, New York, New York, USA
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1755-375X ISBN Medium
Area Expedition Conference
Notes PMID:23742627 Approved no
Call Number IDA @ john @ Serial 346
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Author Bukalev, A.V.; Vinogradova, I.A.; Zabezhinskii, M.A.; Semenchenko, A.V.; Anisimov, V.N.
Title Light pollution increases morbidity and mortality rate from different causes in female rats Type Journal Article
Year 2013 Publication Advances in Gerontology Abbreviated Journal (up) Adv Gerontol
Volume 3 Issue 3 Pages 180-188
Keywords light-at-night; spontaneous tumors; nontumor pathology epiphysis; rats; animals; mammals
Abstract The influence of different light regimes (constant light, LL; constant darkness, DD; standard light regime, LD, 12 hours light/12 hours darkness; and natural lighting of the northwest of Russia (NL) on non-tumor pathology revealed in the post-mortem examination of female rats has been studied. It was found that keeping 25-days-old animals under LL and NL conditions led to an increase in the number of infectious diseases and the substantially faster development of spontaneous tumors (2.9 and 3.3 diseases per one rat, respectively), variety of nontumor pathology found in dead rats, compared with the animals in standard (standard light) regime (1.72 diseases per one rat). Light deprivation (DD) led to a substantial reduction in the development of new growth, as well as nontumor and infectious diseases (1.06 diseases per one rat), compared to the same parameters in a standard light regime.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2079-0570 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number IDA @ john @ Serial 89
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