| Records |
| Author |
Zamorano, J.; de Miguel, A.; Alfaro, E.; MartÃnez-Delgado, D.; Ocaña, F.; Nievas, M.; mez Castaño, J. |
| Title |
NIXNOX project: Enjoy the dark skies of Spain |
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Journal Article |
| Year |
2013 |
Publication |
In Highlights of Spanish Astrophysics VII |
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| Volume |
1 |
Issue |
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Pages  |
962–970 |
| Keywords |
Remote Sensing |
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LoNNe @ kagoburian @ |
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982 |
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De Miguel, A.; Zamorano, J. M.; Gómez Castaño, J.; Ocaña, F.; Pascual RamÃrez, S.; López Cayuela, M. A.,; et al. |
| Title |
). Contaminaci{ó}n lum{Ã}nica en Espa{ñ}a 2012: Light pollution in Spain 2012 |
Type |
Journal Article |
| Year |
2013 |
Publication |
In Highlights of Spanish Astrophysics VII |
Abbreviated Journal |
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| Volume |
1 |
Issue |
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Pages |
956 |
| Keywords |
Remote Sensing |
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no |
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LoNNe @ kagoburian @ |
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926 |
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Bedrosian, T.A.; Weil, Z.M.; Nelson, R.J. |
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Chronic dim light at night provokes reversible depression-like phenotype: possible role for TNF |
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Journal Article |
| Year |
2013 |
Publication |
Molecular Psychiatry |
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| Volume |
18 |
Issue |
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Pages |
930-936 |
| Keywords |
Animals |
| Abstract |
The prevalence of major depression has increased in recent decades and women are twice as likely as men to develop the disorder. Recent environmental changes almost certainly have a role in this phenomenon, but a complete set of contributors remains unspecified. Exposure to artificial light at night (LAN) has surged in prevalence during the past 50 years, coinciding with rising rates of depression. Chronic exposure to LAN is linked to increased risk of breast cancer, obesity and mood disorders, although the relationship to mood is not well characterized. In this study, we investigated the effects of chronic exposure to 5 lux LAN on depression-like behaviors in female hamsters. Using this model, we also characterized hippocampal brain-derived neurotrophic factor expression and hippocampal dendritic morphology, and investigated the reversibility of these changes 1, 2 or 4 weeks following elimination of LAN. Furthermore, we explored the mechanism of action, focusing on hippocampal proinflammatory cytokines given their dual role in synaptic plasticity and the pathogenesis of depression. Using reverse transcription-quantitative PCR, we identified a reversible increase in hippocampal tumor necrosis factor (TNF), but not interleukin-1β, mRNA expression in hamsters exposed to LAN. Direct intracerebroventricular infusion of a dominant-negative inhibitor of soluble TNF, XPro1595, prevented the development of depression-like behavior under LAN, but had no effect on dendritic spine density in the hippocampus. These results indicate a partial role for TNF in the reversible depression-like phenotype observed under chronic dim LAN. Recent environmental changes, such as LAN exposure, may warrant more attention as possible contributors to rising rates of mood disorders. |
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LoNNe @ christopher.kyba @ |
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386 |
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Menegaux, F.; Truong, T.; Anger, A.; Cordina-Duverger, E.; Lamkarkach, F.; Arveux, P.; Kerbrat, P.; Fevotte, J.; Guenel, P. |
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Night work and breast cancer: a population-based case-control study in France (the CECILE study) |
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Journal Article |
| Year |
2013 |
Publication |
International Journal of Cancer. Journal International du Cancer |
Abbreviated Journal |
Int J Cancer |
| Volume |
132 |
Issue |
4 |
Pages |
924-931 |
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Human Health; Adult; Aged; Breast Neoplasms/epidemiology/*etiology; Case-Control Studies; *Circadian Rhythm; Employment; Female; France/epidemiology; Humans; Middle Aged; Occupations; Pregnancy; Risk Factors; *Work Schedule Tolerance |
| Abstract |
Night work involving disruption of circadian rhythm was suggested as a possible cause of breast cancer. We examined the role of night work in a large population-based case-control study carried out in France between 2005 and 2008. Lifetime occupational history including work schedules of each night work period was elicited in 1,232 cases of breast cancer and 1,317 population controls. Thirteen percent of the cases and 11% of the controls had ever worked on night shifts (OR = 1.27 [95% confidence interval = 0.99-1.64]). Odds ratios were 1.35 [1.01-1.80] in women who worked on overnight shifts, 1.40 [1.01-1.92] in women who had worked at night for 4.5 or more years, and 1.43 [1.01-2.03] in those who worked less than three nights per week on average. The odds ratio was 1.95 [1.13-3.35] in women employed in night work for >4 years before their first full-term pregnancy, a period where mammary gland cells are incompletely differentiated and possibly more susceptible to circadian disruption effects. Our results support the hypothesis that night work plays a role in breast cancer, particularly in women who started working at night before first full-term pregnancy. |
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Inserm, CESP Center for research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France; Univ Paris-Sud, UMRS 1018, Villejuif, France |
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English |
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0020-7136 |
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PMID:22689255 |
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no |
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LoNNe @ kagoburian @ |
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781 |
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Gaston, K.J.; Bennie, J.; Davies, T.W.; Hopkins, J. |
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The ecological impacts of nighttime light pollution: a mechanistic appraisal |
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Journal Article |
| Year |
2013 |
Publication |
Biological Reviews of the Cambridge Philosophical Society |
Abbreviated Journal |
Biol Rev Camb Philos Soc |
| Volume |
88 |
Issue |
4 |
Pages |
912-927 |
| Keywords |
dark; information; light; moonlight; night; pollution; resources; rhythms; time |
| Abstract |
The ecological impacts of nighttime light pollution have been a longstanding source of concern, accentuated by realized and projected growth in electrical lighting. As human communities and lighting technologies develop, artificial light increasingly modifies natural light regimes by encroaching on dark refuges in space, in time, and across wavelengths. A wide variety of ecological implications of artificial light have been identified. However, the primary research to date is largely focused on the disruptive influence of nighttime light on higher vertebrates, and while comprehensive reviews have been compiled along taxonomic lines and within specific research domains, the subject is in need of synthesis within a common mechanistic framework. Here we propose such a framework that focuses on the cross-factoring of the ways in which artificial lighting alters natural light regimes (spatially, temporally, and spectrally), and the ways in which light influences biological systems, particularly the distinction between light as a resource and light as an information source. We review the evidence for each of the combinations of this cross-factoring. As artificial lighting alters natural patterns of light in space, time and across wavelengths, natural patterns of resource use and information flows may be disrupted, with downstream effects to the structure and function of ecosystems. This review highlights: (i) the potential influence of nighttime lighting at all levels of biological organisation (from cell to ecosystem); (ii) the significant impact that even low levels of nighttime light pollution can have; and (iii) the existence of major research gaps, particularly in terms of the impacts of light at population and ecosystem levels, identification of intensity thresholds, and the spatial extent of impacts in the vicinity of artificial lights. |
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Environment and Sustainability Institute, University of Exeter, Penryn, Cornwall, TR10 9EZ, U.K |
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English |
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0006-3231 |
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PMID:23565807 |
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no |
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IDA @ john @ |
Serial |
14 |
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