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Author Rahman, S.A.; St Hilaire, M.A.; Gronfier, C.; Chang, A.-M.; Santhi, N.; Czeisler, C.A.; Klerman, E.B.; Lockley, S.W.
Title Functional decoupling of melatonin suppression and circadian phase resetting in humans Type Journal Article
Year 2018 Publication The Journal of Physiology Abbreviated Journal J Physiol
Volume 596 Issue (down) 11 Pages 2147-2157
Keywords Human Health
Abstract KEY POINTS: There is assumed to be a monotonic association between melatonin suppression and circadian phase resetting induced by light exposure. We tested the association between melatonin suppression and phase resetting in humans. Sixteen young healthy participants received nocturnal bright light ( approximately 9500 lux) exposure of continuous or intermittent patterns, and different durations ranging from 12 min to 6.5 h. Intermittent exposure patterns showed significant phase shifts with disproportionately less melatonin suppression. Each and every bright light stimulus in an intermittent exposure pattern induced a similar degree of melatonin suppression, but did not appear to cause an equal magnitude of phase shift. These results suggest that phase shifts and melatonin suppression are functionally independent such that one cannot be used as a proxy measure of the other. ABSTRACT: Continuous experimental light exposures show that, in general, the conditions that produce greater melatonin suppression also produce greater phase shift, leading to the assumption that one can be used as a proxy for the other. We tested this association in 16 healthy individuals who participated in a 9-day inpatient protocol by assessing melatonin suppression and phase resetting in response to a nocturnal light exposure (LE) of different patterns: (i) dim-light control (<3 lux; n = 6) or (ii) two 12-min intermittent bright light pulses (IBL) separated by 36 min of darkness ( approximately 9500 lux; n = 10). We compared these results with historical data from additional LE patterns: (i) dim-light control (<3 lux; n = 11); (ii) single continuous bright light exposure of 12 min (n = 9), 1.0 h (n = 10) or 6.5 h (n = 6); or (iii) an IBL light pattern consisting of six 15-min pulses with 1.0 h dim-light recovery intervals between them during a total of 6.5 h (n = 7). All light exposure groups had significantly greater phase-delay shifts than the dim-light control condition (P < 0.0001). While a monotonic association between melatonin suppression and circadian phase shift was observed, intermittent exposure patterns showed significant phase shifts with disproportionately less melatonin suppression. Each and every IBL stimulus induced a similar degree of melatonin suppression, but did not appear to cause an equal magnitude of phase shift. These results suggest unique specificities in how light-induced phase shifts and melatonin suppression are mediated such that one cannot be used as a proxy measure of the other.
Address Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0022-3751 ISBN Medium
Area Expedition Conference
Notes PMID:29707782 Approved no
Call Number GFZ @ kyba @ Serial 1887
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Author Mortazavi, S.M.J.
Title Comment on 'Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study' Type Journal Article
Year 2018 Publication British Journal of Cancer Abbreviated Journal Br J Cancer
Volume 118 Issue (down) 11 Pages 1536
Keywords Commentary
Abstract
Address Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, Iran. S.M.Javad.Mortazavi@fccc.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-0920 ISBN Medium
Area Expedition Conference
Notes PMID:29769746 Approved no
Call Number GFZ @ kyba @ Serial 1911
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Author Ernst, S.; Łabuz, M.; Środa, K.; Kotulski, L.
Title Graph-Based Spatial Data Processing and Analysis for More Efficient Road Lighting Design Type Journal Article
Year 2018 Publication Sustainability Abbreviated Journal Sustainability
Volume 10 Issue (down) 11 Pages 3850
Keywords Lighting
Abstract The efficiency and affordability of modern street lighting equipment are improving quickly, but systems used to manage and design lighting installations seem to lag behind. One of their problems is the lack of consistent methods to integrate all relevant data. Tools used to manage lighting infrastructure are not aware of the geographic characteristics of the lit areas, and photometric calculation software requires a lot of manual editing by the designer, who needs to assess the characteristics of roads, define the segments, and assign the lighting classes according to standards. In this paper, we propose a graph-based method to integrate geospatial data from various sources to support the process of data preparation for photometric calculations. The method uses graph transformations to define segments and assign lighting classes. A prototype system was developed to conduct experiments using real-world data. The proposed approach is compared to results obtained by professional designers in a case study; the method was also applied to several European cities to assess its efficiency. The obtained results are much more fine-grained than those yielded by the traditional approach; as a result, the lighting is more adequate, especially when used in conjunction with automated optimisation tools.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2071-1050 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 2051
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Author Li, X.; Zhao, L.; Li, D.; Xu, H.
Title Mapping Urban Extent Using Luojia 1-01 Nighttime Light Imagery Type Journal Article
Year 2018 Publication Sensors (Basel, Switzerland) Abbreviated Journal Sensors (Basel)
Volume 18 Issue (down) 11 Pages
Keywords Instrumentation; Remote Sensing
Abstract Luojia 1-01 satellite, launched on 2 June 2018, provides a new data source of nighttime light at 130 m resolution and shows potential for mapping urban extent. In this paper, using Luojia 1-01 and VIIRS nighttime light imagery, we compared several methods for extracting urban areas, including Human Settlement Index (HSI), Simple Thresholding Segmentation (STS) and SVM supervised classification. According to the accuracy assessment, the HSI method using LJ1-01 data had the best performance in urban extent extraction, which presented the largest Kappa Coefficient value, 0.834, among all the results. For the urban areas extracted by VIIRS based HSI method, the largest Kappa Coefficient value was 0.772. In contrast, the largest Kappa Coefficient values obtained by STS method were 0.79 and 0.7512 respectively when using LJ1-01 and VIIRS data, while for SVM method the values were 0.7829 and 0.7486 when using Landsat-LJ and Landsat-VIIRS composite data respectively. The experimented results demonstrated that the utilization of nighttime light imagery can largely improve the accuracy of urban extent extraction and LJ1-01 data, with a higher resolution and more abundant spatial information, can lead to better identification results than its predecessors.
Address Key Laboratory of the Ministry of Land and Resources for Law Evaluation Engineering, Wuhan 430074, China. xuhuimin1985_2008@163.com
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1424-8220 ISBN Medium
Area Expedition Conference
Notes PMID:30380616 Approved no
Call Number GFZ @ kyba @ Serial 2056
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Author Min, J.-young; Min, K.-bok
Title Outdoor Artificial Nighttime Light and Use of Hypnotic Medications in Older Adults: A Population-Based Cohort Study Type Journal Article
Year 2018 Publication Journal of Clinical Sleep Medicine Abbreviated Journal Jcsm
Volume 14 Issue (down) 11 Pages 1903-1910
Keywords Human Health; Remote Sensing
Abstract Study Objectives

Outdoor artificial nighttime light is increasingly recognized as a form of environmental pollution. Excessive nighttime light exposure, whether from indoor or outdoor sources, has been associated with a number of deleterious effects on human health. We performed a population-based cohort study in South Korea to assess the possible association between outdoor nocturnal lighting and insomnia in older adults, as measured by prescriptions for hypnotic drugs.

Methods

This study used data from the 2002–2013 National Health Insurance Service-National Sample Cohort (NHIS-NSC), and a total of 52,027 adults who were age 60 years or older were included in the study. Light data were based on satellite mapping of artificial light. The usage data of two hypnotic drugs, zolpidem (N05CF02) and triazolam (N05CD05), were extracted from the NHIS-NSC records.

Results

Of the 52,027 patients in this cohort, 11,738 (22%) had prescriptions for hypnotic drugs. Increasing outdoor artificial nighttime light exposure (stratified by quartile) was associated with an increased prevalence of hypnotic prescriptions and daily dose intake. Compared with individuals in the lowest quartile 1, the regression coefficients for prescription days and daily defined doses of all hypnotic drugs and certain hypotonic drugs were significantly higher among those living in areas with higher outdoor artificial nighttime light (quartiles 2 through 4).

Conclusions

Outdoor artificial nighttime light exposure was significantly associated with prescription of hypnotic drugs in older adults. These findings are consistent with the hypothesis that outdoor artificial nighttime light may cause sleep disturbances.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1550-9389 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 2060
Permanent link to this record