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Author Masri, S.; Sassone-Corsi, P. url  doi
openurl 
  Title The emerging link between cancer, metabolism, and circadian rhythms Type Journal Article
  Year 2018 Publication Nature Medicine Abbreviated Journal Nat Med  
  Volume 24 Issue (down) 12 Pages 1795-1803  
  Keywords Human Health; Review  
  Abstract The circadian clock is a complex cellular mechanism that, through the control of diverse metabolic and gene expression pathways, governs a large array of cyclic physiological processes. Epidemiological and clinical data reveal a connection between the disruption of circadian rhythms and cancer that is supported by recent preclinical data. In addition, results from animal models and molecular studies underscore emerging links between cancer metabolism and the circadian clock. This has implications for therapeutic approaches, and we discuss the possible design of chronopharmacological strategies.  
  Address Department of Biological Chemistry, Center for Epigenetics and Metabolism, INSERM U1233, University of California Irvine, Irvine, CA, USA. psc@uci.edu  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1078-8956 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30523327 Approved no  
  Call Number GFZ @ kyba @ Serial 2135  
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Author Shor, E.; Potavskaya, R.; Kurtz, A.; Paik, I.; Huq, E.; Green, R. url  doi
openurl 
  Title PIF-mediated sucrose regulation of the circadian oscillator is light quality and temperature dependent Type Journal Article
  Year 2018 Publication Genes Abbreviated Journal Genes (Basel)  
  Volume 9 Issue (down) 12 Pages  
  Keywords Plants  
  Abstract Studies are increasingly showing that metabolic and circadian (~24 h) pathways are strongly interconnected, with the circadian system regulating the metabolic state of the cell, and metabolic products feeding back to entrain the oscillator. In plants, probably the most significant impact of the circadian system on metabolism is in its reciprocal regulation of photosynthesis; however, the pathways by which this occurs are still poorly understood. We have previously shown that members of the basic helix-loop-helix (bHLH) transcription factor PHYTOCHROME INTERACTING FACTOR (PIF) family are involved in the photosynthate entrainment of the circadian oscillator. In this paper, using Arabidopsis mutants and overexpression lines, we examine how temperature and light quality affect PIF-mediated sucrose signaling to the oscillator and examine the contributions of individual PIF members. Our results also show that the quality of light is important for PIF signaling, with red and blue lights having the opposite effects, and that temperature affects PIF-mediated sucrose signaling. We propose the light sensitivity of PIF-mediated sucrose entrainment of the oscillator may be important in enabling plants to distinguish between sucrose produced de novo from photosynthesis during the day and the sucrose products of starch degradation at the end of the night.  
  Address Department of Plant and Environmental Sciences, Institute for Life Sciences, Edmond J. Safra Campus, Givat Ram, Hebrew University, Jerusalem 91904, Israel. rgreen@mail.huji.ac.il  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2073-4425 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30551669; PMCID:PMC6316277 Approved no  
  Call Number GFZ @ kyba @ Serial 2155  
Permanent link to this record
 

 
Author Zhao, Z., Zhou, Y., Tan, G., & Li, J. url  doi
openurl 
  Title Research progress about the effect and prevention of blue light on eyes Type Journal Article
  Year 2018 Publication International Journal of Ophthalmology Abbreviated Journal  
  Volume 11 Issue (down) 12 Pages 1999-2003  
  Keywords Vision; Human Health; Review  
  Abstract In recent years, people have become increasingly attentive to light pollution influences on their eyes. In the visible spectrum, short-wave blue light with wavelength between 415 nm and 455 nm is closely related to eye light damage. This high energy blue light passes through the cornea and lens to the retina causing diseases such as dry eye, cataract, age-related macular degeneration, even stimulating the brain, inhibiting melatonin secretion, and enhancing adrenocortical hormone production, which will destroy the hormonal balance and directly affect sleep quality. Therefore, the effect of Blu-rays on ocular is becoming an important concern for the future. We describe blue light's effects on eye tissues, summarize the research on eye injury and its physical prevention and medical treatment.  
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  Notes Approved no  
  Call Number IDA @ intern @ Serial 2313  
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Author Lee, H. url  doi
openurl 
  Title Do We Use Artificial Light Appropriately? Type Journal Article
  Year 2018 Publication Psychiatry Investigation Abbreviated Journal  
  Volume 15 Issue (down) 12 Pages  
  Keywords Commentary; Human Health  
  Abstract  
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  Notes Approved no  
  Call Number IDA @ intern @ Serial 2314  
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Author Rabaza, O.; Molero-Mesa, E.; Aznar-Dols, F.; Gómez-Lorente, D. url  doi
openurl 
  Title Experimental Study of the Levels of Street Lighting Using Aerial Imagery and Energy Efficiency Calculation Type Journal Article
  Year 2018 Publication Sustainability Abbreviated Journal Sustainability  
  Volume 10 Issue (down) 12 Pages 4365  
  Keywords Remote Sensing; Lighting  
  Abstract This article describes an innovative method for measuring lighting levels and other lighting parameters through the use of aerial imagery of towns and cities. Combined with electricity consumption data from smart electricity meters, it was possible to measure the energy efficiency of public lighting installations. The results of this study also confirmed that lighting measurements, installation material, luminaire position, and electricity consumption data can be easily integrated into geographic information systems (GIS). The main advantage of this new methodology is that it provides information about lighting installations in large areas in less time than more conventional procedures. It is thus a more effective way of obtaining the data required to calculate the energy efficiency of lighting levels and electricity consumption. There is even the possibility of generating street lighting maps that provide local administrations with up-to-date information regarding the status of public lighting installations in their city. In this way, modifications or improvements can be made to achieve greater energy savings and, if necessary, to correct the distribution or configuration of public lighting systems to make them more efficient and sustainable. This research studied levels of street lighting and calculated the energy efficiency in various streets of Deifontes (Granada), through the use of aerial imagery.  
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  Series Volume Series Issue Edition  
  ISSN 2071-1050 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2773  
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