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Author Al Zahrani, M.H.; Omar, A.I.; Abdoon, A.M.O.; Ibrahim, A.A.; Alhogail, A.; Elmubarak, M.; Elamin, Y.E.; AlHelal, M.A.; Alshahrani, A.M.; Abdelgader, T.M.; Saeed, I.; El Gamri, T.B.; Alattas, M.S.; Dahlan, A.A.; Assiri, A.M.; Maina, J.; Li, X.H.; Snow, R.W.
Title Cross-border movement, economic development and malaria elimination in the Kingdom of Saudi Arabia Type Journal Article
Year 2018 Publication (up) BMC Medicine Abbreviated Journal BMC Med
Volume 16 Issue 1 Pages 98
Keywords Remote Sensing; Human Health
Abstract Malaria at international borders presents particular challenges with regards to elimination. International borders share common malaria ecologies, yet neighboring countries are often at different stages of the control-to-elimination pathway. Herein, we present a case study on malaria, and its control, at the border between Saudi Arabia and Yemen. Malaria program activity reports, case data, and ancillary information have been assembled from national health information systems, archives, and other related sources. Information was analyzed as a semi-quantitative time series, between 2000 and 2017, to provide a plausibility framework to understand the possible contributions of factors related to control activities, conflict, economic development, migration, and climate. The malaria recession in the Yemeni border regions of Saudi Arabia is a likely consequence of multiple, coincidental factors, including scaled elimination activities, cross-border vector control, periods of low rainfall, and economic development. The temporal alignment of many of these factors suggests that economic development may have changed the receptivity to the extent that it mitigated against surges in vulnerability posed by imported malaria from its endemic neighbor Yemen. In many border areas of the world, malaria is likely to be sustained through a complex congruence of factors, including poverty, conflict, and migration.
Address Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK. rsnow@kemri-wellcome.org
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1741-7015 ISBN Medium
Area Expedition Conference
Notes PMID:29940950 Approved no
Call Number GFZ @ kyba @ Serial 1948
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Author Johns, L.E.; Jones, M.E.; Schoemaker, M.J.; McFadden, E.; Ashworth, A.; Swerdlow, A.J.
Title Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study Type Journal Article
Year 2018 Publication (up) British Journal of Cancer Abbreviated Journal Br J Cancer
Volume 118 Issue Pages 600-606
Keywords Human Health
Abstract BACKGROUND: Circadian disruption caused by exposure to light at night (LAN) has been proposed as a risk factor for breast cancer and a reason for secular increases in incidence. Studies to date have largely been ecological or case-control in design and findings have been mixed. METHODS: We investigated the relationship between LAN and breast cancer risk in the UK Generations Study. Bedroom light levels and sleeping patterns at age 20 and at study recruitment were obtained by questionnaire. Analyses were conducted on 105 866 participants with no prior history of breast cancer. During an average of 6.1 years of follow-up, 1775 cases of breast cancer were diagnosed. Cox proportional hazard models were used to calculate hazard ratios (HRs), adjusting for potential confounding factors. RESULTS: There was no association between LAN level and breast cancer risk overall (highest compared with lowest LAN level at recruitment: HR=1.01, 95% confidence interval (CI): 0.88-1.15), or for invasive (HR=0.98, 95% CI: 0.85-1.13) or in situ (HR=0.96, 95% CI: 0.83-1.11) breast cancer, or oestrogen-receptor (ER) positive (HR=0.98, 95% CI: 0.84-1.14); or negative (HR=1.16, 95% CI: 0.82-1.65) tumours separately. The findings did not differ by menopausal status. Adjusting for sleep duration, sleeping at unusual times (non-peak sleep) and history of night work did not affect the results. Night waking with exposure to light, occurring around age 20, was associated with a reduced risk of premenopausal breast cancer (HR for breast cancer overall=0.74, 95% CI: 0.55-0.99; HR for ER-positive breast cancer=0.69, 95% CI: 0.49-0.97). CONCLUSIONS: In this prospective cohort analysis of LAN, there was no evidence that LAN exposure increased the risk of subsequent breast cancer, although the suggestion of a lower breast cancer risk in pre-menopausal women with a history of night waking in their twenties may warrant further investigation.British Journal of Cancer advance online publication, 23 January 2018; doi:10.1038/bjc.2017.359 www.bjcancer.com.
Address Division of Breast Cancer Research, The Institute of Cancer Research, London SW3 6JB, UK
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-0920 ISBN Medium
Area Expedition Conference
Notes PMID:29360812 Approved no
Call Number LoNNe @ kyba @ Serial 1803
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Author Mortazavi, S.M.J.
Title Comment on 'Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study' Type Journal Article
Year 2018 Publication (up) British Journal of Cancer Abbreviated Journal Br J Cancer
Volume 118 Issue 11 Pages 1536
Keywords Commentary
Abstract
Address Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, Iran. S.M.Javad.Mortazavi@fccc.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-0920 ISBN Medium
Area Expedition Conference
Notes PMID:29769746 Approved no
Call Number GFZ @ kyba @ Serial 1911
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Author Stevens, R.G.
Title Comment on 'Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study' Type Journal Article
Year 2018 Publication (up) British Journal of Cancer Abbreviated Journal Br J Cancer
Volume in press Issue Pages
Keywords Commentary; Human Health
Abstract
Address University of Connecticut, School of Medicine, 263 Farmington Avenue, Farmington, CT, 06032, USA. bugs@uchc.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-0920 ISBN Medium
Area Expedition Conference
Notes PMID:30283145 Approved no
Call Number GFZ @ kyba @ Serial 2035
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Author Kyba, C.C.M.; Spitschan, M.
Title Comment on 'Domestic light at night and breast cancer risk: a prospective analysis of 105000 UK women in the Generations Study' Type Journal Article
Year 2018 Publication (up) British Journal of Cancer Abbreviated Journal Br J Cancer
Volume in press Issue Pages
Keywords Human Health; Commentary
Abstract
Address Department of Experimental Psychology, University of Oxford, Oxford, UK
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-0920 ISBN Medium
Area Expedition Conference
Notes PMID:30584260 Approved no
Call Number GFZ @ kyba @ Serial 2145
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