| Records |
| Author |
Hasler, B.P. |
| Title |
Commentary on Bedroom Light Exposure at Night and the Incidence of Depressive Symptoms: A Longitudinal Study of the HEIJOKYO Cohort (Obayashi et al) |
Type |
Journal Article |
| Year |
2018 |
Publication  |
American Journal of Epidemiology |
Abbreviated Journal |
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| Volume |
187 |
Issue |
3 |
Pages |
435-438 |
| Keywords |
Commentary; Human Health |
| Abstract |
In modern society, we are increasingly disconnected from natural light/dark cycles and beset by round-the-clock exposure to artificial light. Light has powerful effects on physical and mental health, in part via the circadian system, and thus the timing of light exposure dictates whether it is helpful or harmful. In their compelling paper, Obayashi and colleagues offer evidence that light at night can prospectively predict an elevated incidence of depressive symptoms in older adults. Strengths of the study include the longitudinal design and direct, objective assessment of light levels, as well as accounting for multiple plausible confounders during analyses. Follow-up studies should address the study's limitations, including reliance on a global self-report of sleep quality and a two-night assessment of light exposure that may not reliably represent typical light exposure. In addition, experimental studies including physiological circadian measures will be necessary to determine if the light effects on depression are mediated through the circadian system or are so-called “direct†effects of light. In any case, these exciting findings could inform novel new approaches to preventing depressive disorders in older adults. |
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0002-9262 |
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LoNNe @ kyba @ |
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1716 |
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| Author |
Obayashi, K.; Saeki, K.; Kurumatani, N. |
| Title |
Obayashi et al. Respond to “Light at Night Predicts Depression—What Next?” |
Type |
Journal Article |
| Year |
2018 |
Publication |
American Journal of Epidemiology |
Abbreviated Journal |
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| Volume |
187 |
Issue |
3 |
Pages |
439-440 |
| Keywords |
Commentary; Human Health |
| Abstract |
Our research includes some strengths and limitations. The most important strength is objective measurement of light at night (LAN) intensity using a bedside light meter. Most previous studies evaluating the association between LAN and health outcomes have assessed indoor LAN levels using a self-reported questionnaire or outdoor LAN levels using satellite data; however, self-reported indoor LAN levels has not yet been validated with objective measurement and outdoor LAN levels are surrogates for an individual LAN exposure. The second strength of our study includes its longitudinal design using multivariable methods to adjust for confounders, which indicated LAN exposure may be a cause of the incidence of depressive symptoms. Indeed, the depressive score evaluated by questionnaires may be above or below the cut-off value over the short term; therefore, a long-term study considering such unstable outcomes should be conducted. In the current study, LAN exposure was measured for only two nights; thus, an amplitude of LAN intensity has been focused. However, multiple measurements over time in the future study would allow an analysis of fluctuations in LAN exposure, which might be important for circadian physiology. |
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0002-9262 |
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LoNNe @ kyba @ |
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1717 |
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| Author |
Obayashi, K.; Saeki, K.; Kurumatani, N. |
| Title |
Bedroom Light Exposure at Night and the Incidence of Depressive Symptoms: A Longitudinal Study of the HEIJO-KYO Cohort |
Type |
Journal Article |
| Year |
2018 |
Publication |
American Journal of Epidemiology |
Abbreviated Journal |
Am J Epidemiol |
| Volume |
187 |
Issue |
3 |
Pages |
427-434 |
| Keywords |
Human Health; Mental Health; indoor light; geriatrics; Sleep; Sleep Disorders |
| Abstract |
Previous studies have indicated that minimal exposure to light at night (LAN) increases depression risk, even at 5 lux, in nocturnal and diurnal mammals. Although such low-level LAN may affect human circadian physiology, the association between exposure to LAN and depressive symptoms remains uncertain. In the present study, bedroom light intensity was measured objectively, and depressive symptoms were assessed, during 2010-2014 in Nara, Japan. Of 863 participants (mean age = 71.5 years) who did not have depressive symptoms at baseline, 73 participants reported development of depressive symptoms during follow-up (median, 24 months). Compared with the “dark” group (average of <5 lux; n = 710), the LAN group (average of >/=5 lux; n = 153) exhibited a significantly higher depression risk (hazard ratio = 1.89; 95% CI: 1.13, 3.14), according to a Cox proportional hazards model adjusting for age, sex, body mass index, and economic status. Further, the significance remained in a multivariable model adjusting for hypertension, diabetes, and sleep parameters (hazard ratio = 1.72; 95% CI: 1.03, 2.89). Sensitivity analyses using bedroom light data with a cutoff value of >/=10 lux suggested consistent results. In conclusion, these results indicated that exposure to LAN in home settings was independently associated with subsequent depression risk in an elderly general population. |
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Department of Community Health and Epidemiology, Nara Medical University School of Medicine, 840 Shijocho, Kashiharashi, Nara 634-8521, Japan; e-mail: obayashi(at)naramed-u.ac.jp |
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Oxford Academic |
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English |
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English |
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0002-9262 |
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PMID:28992236 |
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IDA @ john @ |
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1815 |
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Behera, S.K.; Mohanta, R. |
| Title |
Total An Investigation into Light Pollution as a Limiting factor for shift of Mass nesting ground at Rushikulya rookery Ganjam Odishas |
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Journal Article |
| Year |
2018 |
Publication |
American Journal of Marine Research and Reviews |
Abbreviated Journal |
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1 |
Issue |
6 |
Pages |
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Animals |
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Illumination due to artificial lights on nesting beaches and from nearby place to nesting beaches is detrimental to sea turtles because it alters critical nocturnal behaviors specifically, their choice of nesting sites and their return path to the sea after nesting. Illuminations perplex the hatchlings to find sea after emerging. Numerous studies conducted in other countries have demonstrated that artificial lights negatively impact on turtles, both female adults as they come to and go from their home beach to lay eggs, and to turtle hatchlings as they seek out the way to the open ocean. In this study we correlated the mass nesting intensity of 5years (2012 to 2018) at Rushikulya mass nesting site to the illumination zone. Illumination due to light conditions on nesting beaches are complex, and measuring light pollution in a way that effectively captures the impacts to sea turtles is difficult. But increase in intensity of illumination on selective mass nesting beaches showed gradual reduction in intensity of preferred nesting site during the mass nesting event. A gradual shift of nesting preference was also observed more toward darker zone. |
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NC @ ehyde3 @ |
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2104 |
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Christie, S.; Vincent, A.D.; Li, H.; Frisby, C.L.; Kentish, S.J.; O'Rielly, R.; Wittert, G.A.; Page, A.J. |
| Title |
A rotating light cycle promotes weight gain and hepatic lipid storage in mice |
Type |
Journal Article |
| Year |
2018 |
Publication |
American Journal of Physiology. Gastrointestinal and Liver Physiology |
Abbreviated Journal |
Am J Physiol Gastrointest Liver Physiol |
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in press |
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Animals |
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Processes involved in regulation of energy balance and intermediary metabolism are aligned to the light-dark cycle. Shift-work and high fat diet (HFD)-induced obesity disrupt circadian rhythmicity and are associated with increased risk of non-alcoholic fatty liver disease (NAFLD). This study aimed to determine the effect of simulating shift work on hepatic lipid accumulation in lean and HFD-mice. C57BL/6 mice fed a standard laboratory diet (SLD) or HFD for 4wks were further allocated to a normal light (NL)-cycle (lights on:0600-1800hr) or rotating light (RL)-cycle (3-days NL and 4-days reversed (lights on:1800-0600hr) repeated) for 8wks. Tissue was collected every 3hrs beginning at 0600hr. HFD-mice gained more weight than SLD-mice, and RL-mice gained more weight than NL-mice. SLD-NL and HFD-NL mice, but not RL-mice, were more active, had higher respiratory quotients and consumed/expended more energy during the dark phase compared to the light phase. Blood glucose and plasma cholesterol and triglyceride concentrations were elevated in HFD and SLD-RL compared to SLD-NL mice. Hepatic glycogen was elevated in HFD compared to SLD-mice. Hepatic triglycerides were elevated in SLD-RL and HFD-mice compared to SLD-NL. Circadian rhythmicity of hepatic acetyl-CoA carboxylase (ACACA) mRNA was phase shifted in SLD-RL and HFD-NL and lost in HFD-RL mice. Hepatic ACACA protein was reduced in SLD-RL and HFD-mice compared to SLD-NL mice. Hepatic adipose triglyceride lipase was elevated in HFD-NL compared to SLD-NL but lower in RL-mice compared to NL-mice irrespective of diet. -Conclusion: A RL-cycle model of shift-work promotes weight gain and hepatic lipid storage even in lean conditions. |
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Adelaide Medical School, University of Adelaide, Australia |
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English |
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0193-1857 |
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PMID:30188750 |
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GFZ @ kyba @ |
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2123 |
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