| Records |
| Author |
Park, C.Y. |
| Title |
Night Light Pollution and Ocular Fatigue |
Type |
Journal Article |
| Year |
2018 |
Publication  |
Journal of Korean Medical Science |
Abbreviated Journal |
J Korean Med Sci |
| Volume |
33 |
Issue |
38 |
Pages |
e257 |
| Keywords |
Commentary; Human Health |
| Abstract |
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| Address |
Department of Ophthalmology, Dongguk University, Ilsan Hospital, Goyang, Korea |
| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1011-8934 |
ISBN |
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Expedition |
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Conference |
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| Notes |
PMID:30220898; PMCID:PMC6137033 |
Approved |
no |
| Call Number |
GFZ @ kyba @ |
Serial |
2011 |
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| Author |
El-Bakry, H.A.; Ismail, I.A.; Soliman, S.S. |
| Title |
Immunosenescence-like state is accelerated by constant light exposure and counteracted by melatonin or turmeric administration through DJ-1/Nrf2 and P53/Bax pathways |
Type |
Journal Article |
| Year |
2018 |
Publication |
Journal of Photochemistry and Photobiology. B, Biology |
Abbreviated Journal |
J Photochem Photobiol B |
| Volume |
186 |
Issue |
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Pages |
69-80 |
| Keywords |
Animals |
| Abstract |
The awareness of the interrelationship between immunosenescence and constant light exposure can provide new insights into the consequences of excessive exposure to light at night due to light pollution or shift work. Here, we investigated whether constant light exposure (LL) acts as an inducer of immunosenescence. We also determined the role of melatonin or turmeric in reversing the putative effects of constant light and explored for the first time the underlying molecular mechanisms. Young (3-4-month-old) rats were exposed daily to LL alone or in combination with each of melatonin and turmeric for 12weeks. A group of aged rats (18-months old; n=6) was used as a reference for natural immunosenescence. Constant light exposure resulted in remarkable pathophysiological alterations resembling those noticed in normal aged rats, manifested as apparent decreases in antioxidant activities as well as Nrf2 and DJ-1 expressions, striking augmentation in oxidative stress, proinflammatory cytokines and expression of TNFalpha, Bax, and p53 genes, and deleterious changes of lymphoid organs, Co-administration of melatonin or turmeric was able to reverse all alterations induced by LL through upregulation of Nrf2/DJ-1 and downregulation of p53/Bax pathways. These data suggest that LL accelerates immunosenescence via oxidative stress and apoptotic pathways. They also demonstrate for the first time that turmeric is comparable to melatonin in boosting the immune function and counteracting the LL-associated immunosenescence. These effects suggest that turmeric supplementation can be used as an inexpensive intervention to prevent circadian disruption-related immunosenescence. However, to validate the effects of turmeric on humans further studies are warranted. |
| Address |
Department of Zoology & Entomology, Faculty of Science, Minia University, Egypt |
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Thesis |
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Place of Publication |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1011-1344 |
ISBN |
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Medium |
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Conference |
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| Notes |
PMID:30015062 |
Approved |
no |
| Call Number |
GFZ @ kyba @ |
Serial |
1984 |
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| Author |
Kozaki, T.; Hidaka, Y.; Takakura, J.-Y.; Kusano, Y. |
| Title |
Suppression of salivary melatonin secretion under 100-Hz flickering and non-flickering blue light |
Type |
Journal Article |
| Year |
2018 |
Publication |
Journal of Physiological Anthropology |
Abbreviated Journal |
J Physiol Anthropol |
| Volume |
37 |
Issue |
1 |
Pages |
23 |
| Keywords |
Human Health |
| Abstract |
BACKGROUND: Bright light at night is known to suppress melatonin secretion. Novel photoreceptors named intrinsically photosensitive retinal ganglion cells (ipRGCs) are mainly responsible for projecting dark/bright information to the suprachiasmatic nucleus and thus regulating the circadian system. However, it has been shown that the amplitude of the electroretinogram of ipRGCs is considerably lower under flickering light at 100 Hz than at 1-5 Hz, suggesting that flickering light may also affect the circadian system. Therefore, in this study, we evaluated light-induced melatonin suppression under flickering and non-flickering light. METHODS: Twelve male participants between the ages of 20 and 23 years (mean +/- S.D. = 21.6 +/- 1.5 years) were exposed to three light conditions (dim, 100-Hz flickering, and non-flickering blue light) from 1:00 A.M. to 2:30 A.M., and saliva samples were obtained just before 1:00 A.M. and at 1:15, 1:30, 2:00, and 2:30 A.M. RESULTS: A repeated measures t test with Bonferroni correction showed that at 1:15 A.M., melatonin concentrations were significantly lower following exposure to non-flickering light compared with dim light, whereas there was no significant difference between the dim and 100-Hz flickering light conditions. By contrast, after 1:30 A.M., the mean melatonin concentrations were significantly lower under both 100-Hz flickering and non-flickering light than under dim light. CONCLUSION: Although melatonin suppression rate tended to be lower under 100-Hz flickering light than under non-flickering light at the initial 15 min of the light exposure, the present study suggests that 100-Hz flickering light may have the same impact on melatonin secretion as non-flickering light. |
| Address |
Department of Health and Nutrition Sciences, Nishikyushu University, Kanzaki, Japan |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1880-6791 |
ISBN |
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Medium |
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Conference |
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| Notes |
PMID:30340620 |
Approved |
no |
| Call Number |
GFZ @ kyba @ |
Serial |
2039 |
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| Author |
Lee, S.; Kakitsuba, N.; Katsuura, T. |
| Title |
Do green-blocking glasses enhance the nonvisual effects of white polychromatic light? |
Type |
Journal Article |
| Year |
2018 |
Publication |
Journal of Physiological Anthropology |
Abbreviated Journal |
J Physiol Anthropol |
| Volume |
37 |
Issue |
1 |
Pages |
29 |
| Keywords |
Human Health; Vision |
| Abstract |
BACKGROUND: It is well known that light containing the blue component stimulates the intrinsically photosensitive retinal ganglion cells (ipRGCs) and plays a role in melatonin suppression and pupillary constriction. In our previous studies, we verified that simultaneous exposure to blue and green light resulted in less pupillary constriction than blue light exposure. Hence, we hypothesized that the nonvisual effects of polychromatic white light might be increased by blocking the green component. Therefore, we conducted an experiment using optical filters that blocked blue or green component and examined the nonvisual effects of these lights on pupillary constriction and electroencephalogram power spectra. METHODS: Ten healthy young males participated in this study. The participant sat on a chair with his eyes facing an integrating sphere. After 10 min of light adaptation, the participant's left eye was exposed to white pulsed light (1000 lx; pulse width 2.5 ms) every 10 s with a blue-blocking glasses, a green-blocking glasses, or control glasses (no lens), and pupillary constriction was measured. Then, after rest for 10 min, the participant was exposed a continuous white light of 1000 lx with a blue- or green-blocking glasses or control glasses and electroencephalogram was measured. RESULTS: Pupillary constriction with the blue-blocking glasses was significantly less than that observed with the green-blocking glasses. Furthermore, pupillary constriction under the green-blocking glasses was significantly greater than that observed with the control glasses. CONCLUSIONS: A reduction in the green component of light facilitated pupillary constriction. Thus, the effects of polychromatic white light containing blue and green components on ipRGCs are apparently increased by removing the green component. |
| Address |
Graduate School of Engineering, Chiba University, Chiba, Japan |
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English |
Summary Language |
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1880-6791 |
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| Notes |
PMID:30563575; PMCID:PMC6299521 |
Approved |
no |
| Call Number |
GFZ @ kyba @ |
Serial |
2153 |
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| Author |
Hänel, A.; Posch, T.; Ribas, S.J.; Aubé, M.; Duriscoe, D.; Jechow, A.; Kolláth, Z.; Lolkema, D.E.; Moore, C.; Schmidt, N.; Spoelstra, H.; Wuchterl, G.; Kyba, C.C.M. |
| Title |
Measuring night sky brightness: methods and challenges |
Type |
Journal Article |
| Year |
2018 |
Publication |
Journal of Quantitative Spectroscopy and Radiative Transfer |
Abbreviated Journal |
Journal of Quantitative Spectroscopy and Radiative Transfer |
| Volume |
205 |
Issue |
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Pages |
278-290 |
| Keywords |
skyglow |
| Abstract |
Measuring the brightness of the night sky has become an increasingly important topic in recent years, as artificial lights and their scattering by the Earthâ??s atmosphere continue spreading around the globe. Several instruments and techniques have been developed for this task. We give an overview of these, and discuss their strengths and limitations. The different quantities that can and should be derived when measuring the night sky brightness are discussed, as well as the procedures that have been and still need to be defined in this context. We conclude that in many situations, calibrated consumer digital cameras with fisheye lenses provide the best relation between ease-of-use and wealth of obtainable information on the night sky. While they do not obtain full spectral information, they are able to sample the complete sky in a period of minutes, with colour information in three bands. This is important, as given the current global changes in lamp spectra, changes in sky radiance observed only with single band devices may lead to incorrect conclusions regarding long term changes in sky brightness. The acquisition of all-sky information is desirable, as zenith-only information does not provide an adequate characterization of a site. Nevertheless, zenith-only single-band one-channel devices such as the â??Sky Quality Meterâ? continue to be a viable option for long-term studies of night sky brightness and for studies conducted from a moving platform. Accurate interpretation of such data requires some understanding of the colour composition of the sky light. We recommend supplementing long-term time series derived with such devices with periodic all-sky sampling by a calibrated camera system and calibrated luxmeters or luminance meters. |
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Original Title |
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Series Title |
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Edition |
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| ISSN |
0022-4073 |
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Approved |
no |
| Call Number |
LoNNe @ kyba @; GFZ @ kyba @ |
Serial |
1731 |
| Permanent link to this record |
