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Author Wittenbrink, N.; Ananthasubramaniam, B.; Munch, M.; Koller, B.; Maier, B.; Weschke, C.; Bes, F.; de Zeeuw, J.; Nowozin, C.; Wahnschaffe, A.; Wisniewski, S.; Zaleska, M.; Bartok, O.; Ashwal-Fluss, R.; Lammert, H.; Herzel, H.; Hummel, M.; Kadener, S.; Kunz, D.; Kramer, A.
Title High-accuracy determination of internal circadian time from a single blood sample Type Journal Article
Year 2018 Publication The Journal of Clinical Investigation Abbreviated Journal J Clin Invest
Volume 128 Issue 9 Pages 3826-3839
Keywords Human Health
Abstract BACKGROUND: The circadian clock is a fundamental and pervasive biological program that coordinates 24-hour rhythms in physiology, metabolism, and behavior, and it is essential to health. Whereas therapy adapted to time of day is increasingly reported to be highly successful, it needs to be personalized, since internal circadian time is different for each individual. In addition, internal time is not a stable trait, but is influenced by many factors, including genetic predisposition, age, sex, environmental light levels, and season. An easy and convenient diagnostic tool is currently missing. METHODS: To establish a validated test, we followed a 3-stage biomarker development strategy: (a) using circadian transcriptomics of blood monocytes from 12 individuals in a constant routine protocol combined with machine learning approaches, we identified biomarkers for internal time; and these biomarkers (b) were migrated to a clinically relevant gene expression profiling platform (NanoString) and (c) were externally validated using an independent study with 28 early or late chronotypes. RESULTS: We developed a highly accurate and simple assay (BodyTime) to estimate the internal circadian time in humans from a single blood sample. Our assay needs only a small set of blood-based transcript biomarkers and is as accurate as the current gold standard method, dim-light melatonin onset, at smaller monetary, time, and sample-number cost. CONCLUSION: The BodyTime assay provides a new diagnostic tool for personalization of health care according to the patient's circadian clock. FUNDING: This study was supported by the Bundesministerium fur Bildung und Forschung, Germany (FKZ: 13N13160 and 13N13162) and Intellux GmbH, Germany.
Address Charite Universitatsmedizin Berlin, corporate member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, Laboratory of Chronobiology, Berlin, Germany
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0021-9738 ISBN Medium
Area Expedition Conference
Notes PMID:29953415; PMCID:PMC6118629 Approved no
Call Number GFZ @ kyba @ Serial (down) 2194
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Author Meier, J.
Title Contentious Light: An Analytical Framework for Lighting Conflicts Type Journal Article
Year 2018 Publication International Journal of Sustainable Lighting Abbreviated Journal
Volume 20 Issue 1 Pages 62-77
Keywords Society; Lighting; Planning
Abstract This paper takes into view the broad range of contemporary conflicts regarding outdoor lighting. It proposes a working-definition that allows for differentiating lighting conflicts from other forms of lighting-related contention, as well as an analytical framework that allows for the structured description of individual lighting conflicts, and the comparative analysis of multiple cases. The analytical framework was developed based on the social-scientific analysis of media reports of existing conflict cases in Europe and North America, and informed by existing knowledge from the fields of lighting and conflict studies. A central challenge for developing such a framework is dealing with the high level of contingency and complexity of lighting conflicts. The framework reduces this complexity by focusing its field of vision to those aspects that are directly related to the lighting and its contestation. For each of these aspects, it provides sets of descriptive variables that allow for describing the conflicts’ individuality in a standardized – and thus comparable – way. The framework strictly separates the regarded aspects from their judgment by the conflict parties, making it possible to contrast their views on one and the same lighting situation. A visual template supports the process of analysis. It allows for depicting individual cases in short, and for clearly identifying where perspectives differ. At the multiple-case level, the framework not only opens up possibilities for spatial and temporal comparisons of lighting conflicts and the subsequent development of typologies, but also for harnessing their potential for informing the development of more sustainable planning and policy approaches for artificial lighting.
Address Department of Urban and Regional Planning, Technische Universität Berlin, Germany; josiane.meier(at)tu-berlin.de
Corporate Author Thesis
Publisher IJSL Place of Publication Editor
Language English Summary Language English Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial (down) 2190
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Author Bará, S., Ulla, A.
Title Light Pollution in the Galician Atlantic Islands Maritime-Terrestrial National Park 2018 Report Type Report
Year 2018 Publication Abbreviated Journal
Volume Issue Pages
Keywords Conservation; Spain; Galicia; Europe; national park
Abstract The Galician Atlantic Islands Maritime-Terrestrial National Park (PNMTIAG), with the exception of the island of Cortegada, still has night skies of acceptable quality. However, the PNMTIAG islands are under strong photic pressures, both internal and external, that hinder the preservation of the basic features of the natural night, and call for an immediate action of all concerned stakeholders
Address
Corporate Author Thesis
Publisher USC Tragsa Place of Publication Editor
Language Galician Summary Language Galician Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number IDA @ john @ Serial (down) 2187
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Author Oozeki, Y.; Inagake, D.; Saito, T.; Okazaki, M.; Fusejima, I.; Hotai, M.; Watanabe, T.; Sugisaki, H.; Miyahara, M.
Title Reliable estimation of IUU fishing catch amounts in the northwestern Pacific adjacent to the Japanese EEZ: Potential for usage of satellite remote sensing images Type Journal Article
Year 2018 Publication Marine Policy Abbreviated Journal Marine Policy
Volume 88 Issue Pages 64-74
Keywords Remote Sensing
Abstract To establish an estimation procedure for reliable catch amount of illegal, unreported and unregulated (IUU) fishing, light-gathering fishing operations in the northwestern Pacific were analyzed based on the Visible Infrared Imaging Radiometer Suite (VIIRS) day/night band (DNB) data provided by the Suomi National Polar Partnership (SNPP) satellite. The estimated fishing activities were compared with the navigation tracks of vessels obtained from the automatic identification system (AIS). As a model case, the fishing activities of Chinese fishing boats using fish aggregation lights outside the Japanese EEZ in the northwestern Pacific were analyzed from mid-June to early-September 2016. Integration analyses of VIIRS DNB data and AIS information provided reliable data for estimating the fishing activities of Chinese fishing boats and suggested the importance of estimating fish carrier ship movements. The total amount of the chub mackerel (Scomber japonicus) catch during this period was independently estimated from three angles: 1) the fishing capacity of the fishing boats, 2) the freezing capacity of refrigeration factory ships and 3) the fish hold capacity of the fish carrier ships, based on information obtained from interviews with Chinese fisheries companies. These estimates indicated that the total amount of mackerel catch by Chinese fisheries was more than 80% of the allowable biological catch (ABC) of Japan in this area in 2016. This suggests that Pacific high seas fishing has a significant impact on the future of fish abundance. Our proposed procedure raises the possibility of evaluating the fishing impact of some forms of IUU fisheries independently from conventional statistical reports.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0308597X ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial (down) 2179
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Author Kuffer, M.; Pfeffer, K.; Sliuzas, R.; Taubenbock, H.; Baud, I.; van Maarseveen, M.
Title Capturing the Urban Divide in Nighttime Light Images From the International Space Station Type Journal Article
Year 2018 Publication IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing Abbreviated Journal IEEE J. Sel. Top. Appl. Earth Observations Remote Sensing
Volume 11 Issue 8 Pages 2578-2586
Keywords Remote Sensing
Abstract Earlier studies utilizing coarse resolution DMSP-OLS nighttime light (NTL) imagery suggest a negative correlation between the amount of NTL and urban deprivation. The International Space Station (ISS) NTL images offer higher resolution images compared to DMSP-OLS or VIIRS images, allowing an analysis of intraurban NTL variations. The aim of this study is to examine the capacity of ISS images for analyzing the intraurban divide. NTL images of four cities (one African, two Asian, and one South American) have been processed and analyzed. The results show that deprived areas are generally the darker spots of built-up areas within cities, illustrating the urban divide in terms of access to street lighting. However, differences exist between cities: Deprived areas in the African city (Dar es Salaam) generally feature lower NTL emissions compared to the examined cities in South America (Belo Horizonte) and Asia (Mumbai and Ahmedabad). Beyond, variations exist in NTL emissions across deprived areas within cities. Deprived areas at the periphery show less NTL compared to central areas. Edges of deprived areas have higher NTL emissions compared to internal areas. NTL emission differences between types of deprived areas were detected. The correlation between ISS NTL images and population densities is weak; this can be explained by densely built-up deprived areas having less NTL compared to lower density formal areas. Our findings show ISS data complement other data to capture the urban divide between deprived and better-off areas and the need to consider socioeconomic conditions in estimating populations.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1939-1404 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial (down) 2178
Permanent link to this record