| Records |
| Author |
Petritoli, E.; Leccese, F.; Pizzuti, S.; Pieroni, F. |
| Title |
Smart Lighting as basic building block of Smart City: an energy performance comparative case study |
Type |
Journal Article |
| Year |
2018 |
Publication |
Measurement |
Abbreviated Journal |
Measurement |
| Volume |
in press |
Issue |
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Pages |
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| Keywords |
Energy |
| Abstract |
The aim of this work is to simulate and compare the energy savings potentially applicable to the consumption data of the Smart Street pilot system located at the ENEA Casaccia R.C. (Rome). The astronomical lighting system energy consumption (baseline) is compared to the simulation of a pre-defined regulation: it allows the lights dimming (and therefore a reduction of consumptions) based on a statistics averages of the traffic flow rate, differentiated according to the day of the week. Then the baseline consumption is compared to the simulation of an adaptive configuration based on the traffic flow rate. |
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| ISSN |
0263-2241 |
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no |
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GFZ @ kyba @ |
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2147 |
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| Author |
Flores, D.E.F.L.; Oda, G.A. |
| Title |
Novel Light/Dark Regimens with Minimum Light Promote Circadian Disruption: Simulations with a Model Oscillator |
Type |
Journal Article |
| Year |
2018 |
Publication |
Journal of Biological Rhythms |
Abbreviated Journal |
J Biol Rhythms |
| Volume |
in press |
Issue |
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Pages |
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| Keywords |
Animals |
| Abstract |
Artificial lab manipulation of LD cycles has enabled simulations of the disruptive conditions found in modern human societies, such as jet-lag, night-work and light at night. New techniques using animal models have been developed, and these can greatly improve our understanding of circadian disruption. Some of these techniques, such as in vivo bioluminescence assays, require minimum external light. This requirement is challenging because the usual lighting protocols applied in circadian desynchronization experiments rely on considerable light input. Here, we present a novel LD regimen that can disrupt circadian rhythms with little light per day, based on computer simulations of a model limit-cycle oscillator. The model predicts that a single light pulse per day has the potential to disturb rhythmicity when pulse times are randomly distributed within an interval. Counterintuitively, the rhythm still preserves an underlying 24-h periodicity when this interval is as large as 14 h, indicating that day/night cues are still detectable. Only when pulses are spread throughout the whole 24-h day does the rhythm lose any day-to-day period correlation. In addition, the model also reveals that stronger pulses of brighter light should exacerbate the disrupting effects. We propose the use of this LD schedule-which would be compatible with the requirements of in vivo bioluminescence assays-to help understand circadian disruption and associated illnesses. |
| Address |
Instituto de Biociencias, Universidade de Sao Paulo, Sao Paulo, SP, Brazil |
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English |
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| ISSN |
0748-7304 |
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| Notes |
PMID:30595077 |
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no |
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GFZ @ kyba @ |
Serial |
2146 |
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Kyba, C.C.M.; Spitschan, M. |
| Title |
Comment on 'Domestic light at night and breast cancer risk: a prospective analysis of 105000 UK women in the Generations Study' |
Type |
Journal Article |
| Year |
2018 |
Publication |
British Journal of Cancer |
Abbreviated Journal |
Br J Cancer |
| Volume |
in press |
Issue |
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Pages |
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| Keywords |
Human Health; Commentary |
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| Address |
Department of Experimental Psychology, University of Oxford, Oxford, UK |
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English |
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| ISSN |
0007-0920 |
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| Notes |
PMID:30584260 |
Approved |
no |
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GFZ @ kyba @ |
Serial |
2145 |
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| Author |
Zubidat, A.E.; Fares, B.; Fares, F.; Haim, A. |
| Title |
Artificial Light at Night of Different Spectral Compositions Differentially Affects Tumor Growth in Mice: Interaction With Melatonin and Epigenetic Pathways |
Type |
Journal Article |
| Year |
2018 |
Publication |
Cancer Control : Journal of the Moffitt Cancer Center |
Abbreviated Journal |
Cancer Control |
| Volume |
25 |
Issue |
1 |
Pages |
1073274818812908 |
| Keywords |
Human Health; 6-Smt; Cfl; EE-halogen; GDM-levels; body mass; carbon; corticosterone; cosinor analysis; light at night; yellow-LED |
| Abstract |
Lighting technology is rapidly advancing toward shorter wavelength illuminations that offer energy-efficient properties. Along with this advantage, the increased use of such illuminations also poses some health challenges, particularly breast cancer progression. Here, we evaluated the effects of artificial light at night (ALAN) of 4 different spectral compositions (500-595 nm) at 350 Lux on melatonin suppression by measuring its urine metabolite 6-sulfatoxymelatonin, global DNA methylation, tumor growth, metastases formation, and urinary corticosterone levels in 4T1 breast cancer cell-inoculated female BALB/c mice. The results revealed an inverse dose-dependent relationship between wavelength and melatonin suppression. Short wavelength increased tumor growth, promoted lung metastases formation, and advanced DNA hypomethylation, while long wavelength lessened these effects. Melatonin treatment counteracted these effects and resulted in reduced cancer burden. The wavelength suppression threshold for melatonin-induced tumor growth was 500 nm. These results suggest that short wavelength increases cancer burden by inducing aberrant DNA methylation mediated by the suppression of melatonin. Additionally, melatonin suppression and global DNA methylation are suggested as promising biomarkers for early diagnosis and therapy of breast cancer. Finally, ALAN may manifest other physiological responses such as stress responses that may challenge the survival fitness of the animal under natural environments. |
| Address |
1 The Israeli Center for Interdisciplinary Research in Chronobiology, University of Haifa, Haifa, Israel |
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SAGE |
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English |
Summary Language |
English |
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1073-2748 |
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| Notes |
PMID:30477310; PMCID:PMC6259078 |
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no |
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IDA @ john @ |
Serial |
2143 |
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| Author |
Studer, P.; Brucker, J.M.; Haag, C.; Van Doren, J.; Moll, G.H.; Heinrich, H.; Kratz, O. |
| Title |
Effects of blue- and red-enriched light on attention and sleep in typically developing adolescents |
Type |
Journal Article |
| Year |
2018 |
Publication |
Physiology & Behavior |
Abbreviated Journal |
Physiol Behav |
| Volume |
199 |
Issue |
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Pages |
11-19 |
| Keywords |
Human Health |
| Abstract |
Differential effects of blue- and red-enriched light on attention and sleep have been primarily described in adults. In our cross-over study in typically developing adolescents (11-17years old), we found attention enhancing effects of blue- compared to red-enriched light in the morning (high intensity of ca. 1000lx, short duration: <1h) in two of three attention tasks: e.g. better performance in math tests and reduced reaction time variability in a computerized attention test. In our pilot study, actigraphy measures of sleep indicated slight benefits for red- compared to blue-enriched light in the evening: tendencies toward a lower number of phases with movement activity after sleep onset in the complete sample and shorter sleep onset latency in a subgroup with later evening exposure times. These findings point to the relevance of light concepts regarding attention and sleep in typically developing adolescents. Such concepts should be developed and tested further in attention demanding contexts (at school) and for therapeutic purposes in adolescents with impaired attention or impaired circadian rhythms. |
| Address |
Department of Child and Adolescent Mental Health, University Hospital Erlangen, Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Erlangen, Germany. Electronic address: oliver.kratz@uk-erlangen.de |
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English |
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0031-9384 |
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| Notes |
PMID:30381244 |
Approved |
no |
| Call Number |
GFZ @ kyba @ |
Serial |
2142 |
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